Pay in installments of $25.00 with
,
and
Shipping Estimate
USA
- USA
- CAN
- USA
- CAN
Ships within 48 hours · Estimated delivery Aug 12 - Aug 17
Promo Codes Available:
For Your Every Summer RSVP, with Code: SUMMER15
Description
Mouse Anti-Human CD95 Antibody (S-3025)Product Specification Host Mouse Antigen CD95 Synonyms Tumor necrosis factor receptor superfamily member 6; Apo 1 antigen; Apoptosis mediating surface antigen FAS; FASLG receptor; APT1; FAS1; TNFRSF6; FAS Location Cell membrane Accession P25445 Clone Number S 3025 Antibody Type Mouse mAb Isotype IgG1,k Application FCM Reactivity Hu Positive Sample Human Peripheral Blood cells Purification Protein G Concentration 2 mg ml Conjugation Unconjugated
Product Specification
| Host | Mouse |
| Antigen | CD95 |
| Synonyms | Tumor necrosis factor receptor superfamily member 6; Apo-1 antigen; Apoptosis-mediating surface antigen FAS; FASLG receptor; APT1; FAS1; TNFRSF6; FAS |
| Location | Cell membrane |
| Accession | P25445 |
| Clone Number | S-3025 |
| Antibody Type | Mouse mAb |
| Isotype | IgG1,k |
| Application | FCM |
| Reactivity | Hu |
| Positive Sample | Human Peripheral Blood cells |
| Purification | Protein G |
| Concentration | 2 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS pH7.4 |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied |
Dilution
| application | dilution | species |
| FCM | 1:200 | Hu |
Background
CD95, also known as Fas or APO-1, is a protein that plays a crucial role in the regulation of apoptosis, or programmed cell death. It is a member of the tumor necrosis factor receptor superfamily and is expressed on the surface of various immune cells, including T cells and B cells. When CD95 is engaged by its ligand, CD95L, it triggers a signaling cascade involving the recruitment of adaptor proteins such as FADD, which in turn activates caspases, leading to the dismantling of the cell. This pathway is essential for maintaining immune homeostasis by eliminating activated or damaged cells. Dysregulation of CD95 signaling has been implicated in a range of diseases, including autoimmune disorders and cancer, highlighting its importance in both physiological and pathological contexts.
Shipping Notes
- Free Standard Shipping on $100+ Orders to the USA.
- Except Preorder products are shipped in 48 hours.
- Delivery to the USA:
- Standard Shipping : 3-10 business days
- If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
- Final sale items are not eligible for returns or exchanges.
- To process your return/exchange, please contact us at [email protected]
- Please click here for more details>>> Return & Exchange Policy