SKU: 74920060640

EWSR1/EWS Recombinant Rat mAb (S-R201)

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Description

EWSR1/EWS Recombinant Rat mAb (S-R201)Product Specification Host Rat Antigen EWSR1 EWS Synonyms RNA binding protein EWS, EWS oncogene, Ewing sarcoma breakpoint region 1 protein Location Cytoplasm, Nucleus, Cell membrane Accession Q01844 Clone Number S R201 Antibody Type Rat mAb Isotype IgG1 Application WB, IHC P, ICC, ICFCM Reactivity Hu, Ms, Rt Purification Protein G Concentration 1 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS, 40% Glycerol, 0. 05% BSA, 0.

Product Specification


Host Rat
Antigen EWSR1/EWS
Synonyms RNA-binding protein EWS, EWS oncogene, Ewing sarcoma breakpoint region 1 protein
Location Cytoplasm, Nucleus, Cell membrane
Accession Q01844
Clone Number S-R201
Antibody Type Rat mAb
Isotype IgG1
Application WB, IHC-P, ICC, ICFCM
Reactivity Hu, Ms, Rt
Purification Protein G
Concentration 1 mg/ml
Conjugation Unconjugated
Physical Appearance Liquid
Storage Buffer PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300
Stability & Storage

12 months from date of receipt / reconstitution, -20 °C as supplied

Dilution


application dilution species
WB 1:5000 null
IHC 1:250 null
ICC 1:250 null
ICFCM 1:500 null

Background

Ewing’s sarcoma (EWS) is a bone cancer arising predominantly in young children. EWSR1 (Ewing Sarcoma breakpoint region 1/EWS RNA binding protein 1) gene is ubiquitously expressed in most cell types, indicating it has diverse roles in various cellular processes and organ development. Recently, several studies have shown that missense mutations of EWSR1 genes are known to be associated with central nervous system disorders such as amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Otherwise, EWSR1 plays epigenetic roles in gene expression, RNA processing, and cellular signal transduction. Interestingly, EWSR1 controls micro RNA (miRNA) levels via Drosha, leading to autophagy dysfunction and impaired dermal development. Ewsr1 deficiency also leads to premature senescence of blood cells and gamete cells with a high rate of apoptosis due to the abnormal meiosis [PMID: 30481590].

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SKU: 74920060640

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4.6 ★★★★★
Based on 7 reviews
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Product Reviews
B
Bluesman
Chelsea, US
★★★★★ 5
Incredibly strong magnets and thick, robust hooks. Excellent combination!
Style: Updated 3.46in Magnet L Red Hooks 2PCS
These magnetic hooks are really strong. Seriously! Each part is made to carry weight and last. The hooks are built out of thick steel stock. They bolt up to large magnets that grab onto steel surfaces and won't let go. The cabinets in my shop are all steel so these worked perfectly on the sides of the lower units. I have a few #12 AWG extension cords that are bulky and heavy. Truthfully, I didn't think these hooks would handle them. They do without any issue. Another application is a 30' long #10/4 AWG SO cable that powers my powder coating oven. It's usually unplugged and wrapped up. It would often end up on the floor where it was constantly in the way. The outside of the oven is all steel but I didn't want to make holes in it for cable hangers. Again, I didn't think that these magnetic hooks could possibly be strong enough to handle the weight of that cable but they do. And once they're attached, it takes a lot of effort to remove them! Amazing performance!! I'm thrilled with these magnetic hooks. They are super strong and, obviously, simple to use. Importantly, they stay in place as they should. I wholeheartedly recommend these hooks to anyone. Great product! Incredibly strong magnets and thick, robust hooks. Excellent combination!
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Reviewed in the United States on May 12, 2026
A
Andrea
Louisville, US
★★★★★ 5
Great for the storm shelter!
Style: Updated 3.46in Magnet L Red Hooks 2PCS, Style: Updated 3.46in Magnet L Red Hooks 2PCS
In our storm shelter we had some lights that we tried to hang up, multiple times, with no luck! Then I found these garage hooks. They are overkill for the lights, but I’m so happy that we now have lighting in the storm shelter. I could think of so many other uses for these. They strength of the magnets is awesome!
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Reviewed in the United States on May 19, 2026
K
KindaPicky
Draper, US
★★★★★ 4
Magnet is super strong but hooks are not adjustable
Style: Updated 3.46in Magnet L Red Hooks 2PCS, Style: Updated 3.46in Magnet L Red Hooks 2PCS
I ordered this set of Mutuactor magnetic hooks because I was tired of thinking I had things organized and then finding previously hung magnets have slid down the wall. It was a first for me to have to assemble a magnetic hook. This was made slightly more difficult by requiring a wrench. So many items these days arrive with a disposable little hex wrench or whatever is needed for assembly. Not in this case. Maybe the manufacturer assumes if you are spending $15 per magnet to hang your tools you have a wrench handy. Anyway, I got my wrench and found no instructions. I know from life that the order is bolt-washer-lock washer-nut. The next question arose when I found one bolt and several holes... hmmmm. It looks like they wanted to provide the option to screw the hooks directly to the wall. I am not sure the average person would pay that price just for a hook, though. I chose a hole and it seems to be the right one. The good news is I was quickly in business. Soon one magnet was snatched by my husband for his rolling tool cart. He hung his (very heavy) Sawzall and the magnet never moved. He liked the rubber coating that protects his tools. I chose to take advantage of the amazing grip of this thing to hang my most used (and also very heavy) all-clad pan from the side of my fridge. The refrigerator had some sort of glossy powder coat and magnets hold well if you try to pull them straight off but end up sliding down anyway. This is where I came to appreciate the rubber shoe of this magnet. It protects my fridge but I think it plays an essential part in the grip strength of the magnet. I can not slide it around - I need to use two hands to pull it off then place it in another position. To give a magnet strength example I had one magnetic hook on my desk as I was writing this review. My nearby desk-size scotch tape dispenser came sliding over and the magnet grabbed it. I was able to lift the tape dispense just by the magnet grabbing the little piece of metal serrated teeth that cut the tape. There is no other metal in my dispenser. That's it! In summary, four stars because it REALLY grips and holds a lot of weight. Minus a star because I do think they are a little expensive, they required assembly without tools or instructions, and the hooks themselves are not adjustable. I have some similar magnetic hooks and you can move the two prongs apart or together depending on what your tool size is. These prongs are strong and firm and are not moving and this cuts down of the number of uses a little bit.
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Reviewed in the United States on March 12, 2026
F
Francisco P.
Birmingham, US
★★★★★ 5
Develop some quality, worth-while hangups!
Style: Updated 3.46in Magnet L Red Hooks 2PCS, Style: Updated 3.46in Magnet L Red Hooks 2PCS
Organization is key for any shop space. This goes double for smaller shops. If you look around and DON'T see something that could benefit from getting off the floor and onto a peg or hook, I applaud you! For the rest of us, where can we get started? Here you go. These hooks come two in a package. The quality of these are easy to see. The powder coating is very nice as powder coating is more durable than paint. The orange plastic coating on the hooks feels thick and durable. Assembly is easy. There's a threaded post sticking out of the black rubber coated magnet "puck" that you insert into a opening on the hook and secure with washers and a nut. I like that they included both a washer and locking washer. If it matters, I always stack the fastener in the following order: washer, locking washer, then nut. Using a 14mm socket, I was done in no time. How's much will these hooks hold? The magnetic power on these hooks feels substantial. When I slowly approached the side of my metal toolbox, the magnet made an audible snap when it magnetized to the side. It felt strong! The bend at the base of the hook added stability pressing against the toolbox but didn't mark the surface since it was covered by plastic. It held my heavy 50a extension cable and the other hook held both my 25' and 50' pressure washer hoses. Neither moved at all and felt very secure. Whether your shop is your garage or basement, making the most of your space makes a difference and these can help. These are very strong and hold items safely. I'm very happy having these around and will be getting more. If you have a metal surface that you can attach hooks, give these a try. It's a quality solution!
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Reviewed in the United States on March 21, 2026
B
Verified Purchase
breezob
Bozeman, US
★★★★★ 1
Not strong
Style: Updated 3.46in Magnet L Red Hooks 2PCS
The magnets are not strong enough to hold garden tools!
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Reviewed in the United States on May 27, 2026

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