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Description
Rabbit CD19, His tagProduct Specification Species Rabbit Accession G1TWR4 Amino Acid Sequence Protein sequence (G1TWR4, Gln21 Gly278, with C 10*His) QKLLQVEMEEGSDAVLPCLQDPPDGPPERLIWSRDSQGPFLELSPGSPGLGIHVGRLGILLLIFNVSNEMGGFYLCQPAPPSQQAWQPGWTVSVEGSGELFRWNASDLGGPGCGLGNESSSSQPYVWDRDHPKEWDMGPACASPRGDLNQSSSLDLTVAPGSTVWLSCGVPPASVATGPVSWAHIHPTKPNILLPSLNLTAESPAREMWVLGPVLMLPQVTAVDAGMYVCRRGNLTTEIHVTITVRPAIWHWLQRKSGGGGGSHHHHHHHHHH Expression System HEK293 Molecular Weight Predicted
Product Specification
| Species | Rabbit |
| Accession | G1TWR4 |
| Amino Acid Sequence | Protein sequence (G1TWR4, Gln21-Gly278, with C-10*His) QKLLQVEMEEGSDAVLPCLQDPPDGPPERLIWSRDSQGPFLELSPGSPGLGIHVGRLGILLLIFNVSNEMGGFYLCQPAPPSQQAWQPGWTVSVEGSGELFRWNASDLGGPGCGLGNESSSSQPYVWDRDHPKEWDMGPACASPRGDLNQSSSLDLTVAPGSTVWLSCGVPPASVATGPVSWAHIHPTKPNILLPSLNLTAESPAREMWVLGPVLMLPQVTAVDAGMYVCRRGNLTTEIHVTITVRPAIWHWLQRKSGGGGGSHHHHHHHHHH |
| Expression System | HEK293 |
| Molecular Weight | Predicted MW: 29.5 kDa Observed MW: 40-65 kDa |
| Purity | ＞95% by SDS-PAGE |
| Tag | with C-10*His |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, pH7.4. |
| Reconstitution | Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation. |
| Stability & Storage | 12 months from date of receipt, -20 to -70 °C as supplied. 6 months, -20 to -70 °C under sterile conditions after reconstitution. 1 week, 2 to 8 °C under sterile conditions after reconstitution. Please avoid repeated freeze-thaw cycles. |
Background
B-lymphocyte antigen CD19, also known as CD19 molecule (Cluster of Differentiation 19), B-Lymphocyte Surface Antigen B4, T-Cell Surface Antigen Leu-12 and CVID3 is a transmembrane protein. CD19 is expressed in all B lineage cells. CD19 plays two major roles in B cells: on the one hand, it acts as an adaptor protein to recruit cytoplasmic signaling proteins to the membrane; on the other, it works within the CD19/CD21 complex to decrease the threshold for B cell receptor signaling pathways. Due to its presence on all B cells, it is a biomarker for B lymphocyte development, lymphoma diagnosis and can be utilized as a target for leukemia immunotherapies.
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