SKU: 7764201265

Rat Anti-Mouse LPAM-1 Antibody (S-3206)

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Description

Rat Anti-Mouse LPAM-1 Antibody (S-3206)Product Specification Host Rat Antigen LPAM 1 Location Cell membrane Accession P26011 Clone Number S 3206 Antibody Type Rat mAb Isotype IgG2a,k Application FCM Reactivity Ms Positive Sample C57BL 6 mouse splenocytes Purification Protein G Concentration 2 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS pH7. 4 Stability & Storage 12 months from date of receipt reconstitution, 2 to 8 C as supplied Dilution application

Product Specification


Host Rat
Antigen LPAM-1
Location Cell membrane
Accession P26011
Clone Number S-3206
Antibody Type Rat mAb
Isotype IgG2a,k
Application FCM
Reactivity Ms
Positive Sample C57BL/6 mouse splenocytes
Purification Protein G
Concentration 2 mg/ml
Conjugation Unconjugated
Physical Appearance Liquid
Storage Buffer

PBS pH7.4

Stability & Storage

12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

Dilution


application dilution species
FCM 1:200 Ms

Background

LPAM-1 (Lymphocyte Peyer’s patch Adhesion Molecule-1), also designated integrin α4β7, is a 150/130 kDa heterodimeric surface glycoprotein of the integrin immunoglobulin superfamily that is constitutively expressed on naive T and B cells, up-regulated on gut-homing memory CD4⁺ T cells and IgA-secreting plasma cells by retinoic acid, and serves as the principal homing receptor mediating rolling and firm adhesion of these leukocytes to mucosal vascular addressin MAdCAM-1 on high endothelial venules of Peyer’s patches and intestinal lamina propria, thereby orchestrating their trans-endothelial migration into gut-associated lymphoid tissues during both steady-state immune surveillance and inflammatory bowel diseases, and can also engage VCAM-1 and fibronectin to support lymphocyte trafficking and retention.

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SKU: 7764201265

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Reviewed in the United States on November 30, 2025
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