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Description
CD48 Recombinant Rabbit mAb (S-R265)Product Specification Host Rabbit Antigen CD48 Synonyms CD48 antigen, B lymphocyte activation marker BLAST 1, BCM1 surface antigen, Leukocyte antigen MEM 102, SLAM family member 2 (SLAMF2), Signaling lymphocytic activation molecule 2, TCT. 1, BCM1, BLAST1 Location Secreted, Cell membrane Accession P09326 Clone Number S R265 Antibody Type Recombinant mAb Application WB, IHC P, ICC Reactivity Hu Purification Protein A Concentration 0. 5 mg ml
Product Specification
| Host | Rabbit |
| Antigen | CD48 |
| Synonyms | CD48 antigen, B-lymphocyte activation marker BLAST-1, BCM1 surface antigen, Leukocyte antigen MEM-102, SLAM family member 2 (SLAMF2), Signaling lymphocytic activation molecule 2, TCT.1, BCM1, BLAST1 |
| Location | Secreted, Cell membrane |
| Accession | P09326 |
| Clone Number | S-R265 |
| Antibody Type | Recombinant mAb |
| Application | WB, IHC-P, ICC |
| Reactivity | Hu |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05%BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | null |
| IHC | 1:500 | null |
| ICC | 1:100 | null |
Background
CD48 is a member of the CD2 subfamily of the immunoglobulin superfamily (IgSF) which includes SLAM (signaling lymphocyte activation molecules) proteins, such as CD84, CD150, CD229 and CD244. CD48 is found on the surface of lymphocytes and other immune cells, dendritic cells and endothelial cells, and participates in activation and differentiation pathways in these cells. CD48 was the first B-cell-specific cellular differentiation antigen identified in transformed B lymphoblasts. CD48 interaction with CD2 has been shown to promote lipid raft formation, T cell activation and the formation of caveolae for macrophages through cell signal transduction via GPI moieties.
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Exchange/Return Notes
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