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Description
NaK-ATPase Recombinant Rabbit mAb (Alexa Fluor® 488 Conjugate) (S-1373-39)Product Specification Host Rabbit Antigen NaK ATPase Synonyms Sodium potassium transporting ATPase subunit alpha 1, Na(+) K(+) ATPase alpha 1 subunit, Sodium pump subunit alpha 1, ATP1A1 Immunogen Synthetic Peptide Location Cell membrane, Melanosome Accession P05023 Clone Number S 1373 39 Antibody Type Recombinant mAb Application IF Reactivity Hu Purification Protein A Conjugation Alexa Fluor 488 Physical Appearance Liquid Storage Buffer PBS, 25%
Product Specification
| Host | Rabbit |
| Antigen | NaK-ATPase |
| Synonyms | Sodium/potassium-transporting ATPase subunit alpha-1, Na(+)/K(+) ATPase alpha-1 subunit, Sodium pump subunit alpha-1, ATP1A1 |
| Immunogen | Synthetic Peptide |
| Location | Cell membrane, Melanosome |
| Accession | P05023 |
| Clone Number | S-1373-39 |
| Antibody Type | Recombinant mAb |
| Application | IF |
| Reactivity | Hu |
| Purification | Protein A |
| Conjugation | Alexa Fluor® 488 |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 25% Glycerol, 1% BSA, 0.3% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied. |
Dilution
| application | dilution | species |
| IF | 1:200 | Hu |
Background
NaK-ATPase, also known as the sodium-potassium adenosine triphosphatase (Na+/K+-ATPase) or simply the sodium pump, is a crucial transmembrane protein found in the plasma membrane of animal cells. Utilizing the energy released from ATP hydrolysis, Na+/K+-ATPase actively transports Na+ ions out of the cell against their concentration gradient while simultaneously transporting K+ ions into the cell. This ion transport activity is essential for maintaining the electrochemical gradients across the cell membrane, contributing to the stability of the intracellular and extracellular environments. In addition to its role as an ion pump, Na+/K+-ATPase has signaling functions. It can serve as a receptor for certain hormones and drugs, participating in intracellular signaling cascades.
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