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Description
Alexa Fluor® 488 Mouse Anti-Mouse CX3CR1 Antibody (S-R597)Product Specification Host Mouse Antigen CX3CR1 Synonyms CX3C chemokine receptor 1; C X3 C CKR 1; mCX3CR1; Fractalkine receptor Location Cell membrane Accession Q9Z0D9 Clone Number S R597 Antibody Type Mouse mAb Isotype IgG2a,k Application FCM Reactivity Ms Positive Sample C57BL 6 mouse splenocytes Purification Protein A Concentration 0. 2 mg ml Conjugation Alexa Fluor 488 Physical Appearance Liquid Storage Buffer PBS, 1% BSA, 0. 3% Proclin 300
Product Specification
| Host | Mouse |
| Antigen | CX3CR1 |
| Synonyms | CX3C chemokine receptor 1; C-X3-C CKR-1; mCX3CR1; Fractalkine receptor |
| Location | Cell membrane |
| Accession | Q9Z0D9 |
| Clone Number | S-R597 |
| Antibody Type | Mouse mAb |
| Isotype | IgG2a,k |
| Application | FCM |
| Reactivity | Ms |
| Positive Sample | C57BL/6 mouse splenocytes |
| Purification | Protein A |
| Concentration | 0.2 mg/ml |
| Conjugation | Alexa Fluor® 488 |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 1% BSA, 0.3% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied |
Dilution
| application | dilution | species |
| FCM | 5μl per million cells in 100μl volume | Ms |
Background
CX3CR1 is a seven-transmembrane G-protein-coupled receptor expressed on monocytes, macrophages, dendritic cells, microglia and tissue-patrolling lymphocytes that serves as the exclusive receptor for the unique membrane-tethered or soluble chemokine CX3CL1 (fractalkine), thereby orchestrating leukocyte adhesion, chemotaxis and survival during development, homeostasis, viral and bacterial infections, inflammatory diseases such as atherosclerosis and rheumatoid arthritis, neuroinflammatory conditions including Alzheimer’s disease, and tumor progression or metastasis, while also acting as a co-receptor for respiratory syncytial virus entry into airway epithelium and modulating antiviral immunity via IL-10 induction.
Shipping Notes
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Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
- Final sale items are not eligible for returns or exchanges.
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