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Description
CD163 Recombinant Rabbit mAb (Alexa Fluor® 555 Conjugate) (S-222-171)Product Specification Host Rabbit Antigen CD163 Synonyms M130, Hemoglobin scavenger receptor Immunogen Synthetic Peptide Location Secreted, Cell membrane Accession Q86VB7 Clone Number S 222 171 Antibody Type Recombinant mAb Isotype IgG Application IF Reactivity Hu Purification Protein A Concentration 2 mg ml Conjugation Alexa Fluor 555 Physical Appearance Liquid Storage Buffer PBS, 0. 1% BSA, 0. 01% Proclin 300 Stability & Storage 12 months from date
Product Specification
| Host | Rabbit |
| Antigen | CD163 |
| Synonyms | M130, Hemoglobin scavenger receptor |
| Immunogen | Synthetic Peptide |
| Location | Secreted, Cell membrane |
| Accession | Q86VB7 |
| Clone Number | S-222-171 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | IF |
| Reactivity | Hu |
| Purification | Protein A |
| Concentration | 2 mg/ml |
| Conjugation | Alexa Fluor® 555 |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 0.1% BSA, 0.01% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied. |
Dilution
| application | dilution | species |
| IF | 1:200 | null |
Background
CD163 is a monocyte/macrophage specific marker expressed predominantly on cells which possess strong anti-inflammatory potential. The expression of CD163 is strongly induced by anti-inflammatory mediators such as glucocorticoids and interleukin-10, while being inhibited by pro-inflammatory mediators such as interferon-gamma. CD163-expressing mononuclear phagocytes, as well as soluble CD163, may both take part in downregulating an inflammatory response [PubMed: 22038213].
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