SKU: 87316409981

ENO-2(NSE) Protein, Human

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Description

ENO-2(NSE) Protein, HumanProduct Specification Species Human Synonyms ENO 2(NSE); Gamma enolase,2 phospho D glycerate hydro lyase,Enolase 2,Neural enolase,Neuron specific enolase,NSE,ENO2 Accession P09104 Amino Acid Sequence

Product Specification


Species Human
Synonyms ENO-2(NSE);Gamma-enolase,2-phospho-D-glycerate hydro-lyase,Enolase 2,Neural enolase,Neuron-specific enolase,NSE,ENO2
Accession P09104
Amino Acid Sequence

MHHHHHHDDDDKSIEKIWAREILDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDGDKQRYLGKGVLKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCKAGAAERELPLYRHIAQLAGNSDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRDAMRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYTEKIVIGMDVAASEFYRDGKYDLDFKSPTDPSRYITGDQLGALYQDFVRDYPVVSIEDPFDQDDWAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACKLAQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEELGDEARFAGHNFRNPSVL

Expression System E.coli
Molecular Weight

48.7kDa(Reducing)

Purity >95%, by SDS-PAGE under reducing conditions
Endotoxin <1EU/μg
Conjugation Unconjugated
Tag His Tag
Physical Appearance Lyophilized Powder
Storage Buffer PBS, pH6.7
Reconstitution

Reconstitute at less than 1 mg/mL according to the size in ultrapure water after rapid centrifugation .

Stability & Storage · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.

Background

Neuron-specific enolase (neuron-specific enolase, NSE) is one of the enolases involved in glycolysis, which exists in nerve tissue and neuroendocrine tissue. The activity of NSE in brain tissue was the highest, the activity level of peripheral nerve and neurosecretory tissue was in the middle, and the lowest value was found in non-nerve tissue, serum and spinal fluid. It has been found to be a tumor marker of lung cancer and neuroblastoma and can be used for differential diagnosis, disease monitoring, curative effect evaluation and recurrence prediction. Monitoring the recurrence of small cell lung cancer with neuron-specific enolase is 4-12 weeks earlier than the clinical determination of recurrence. Neuron-specific enolase can also be used in the differential diagnosis of neuroblastoma and nephroblastoma. The former increases abnormally while the latter does not increase significantly. Increase: seen in small cell lung cancer, neuroblastoma, neuroendocrine cell tumors (such as pheochromocytoma, islet cell tumor, melanoma) and so on.

Shipping Notes
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Exchange/Return Notes
  • We offer a 30-day return/exchange service after receiving.
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  • To process your return/exchange, please contact us at [email protected]
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SKU: 87316409981

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4.2 ★★★★★
Based on 28 reviews
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Product Reviews
M
Verified Purchase
M D S
Draper, US
★★★★★ 3
Dog loved it, wish it had lasted - better suited for light chewers
Color: Stick
Our puppy was able to pull the rope out of the rubber piece within a day or so. Unfortunately, he then started chewing on the blue rubber piece and had it destroyed in no time. Once the pieces started coming off, we had to throw it away to prevent him from ingesting it.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on March 20, 2021
B
Verified Purchase
Bernardka Vesel
Louisville, US
★★★★★ 5
great for teething puppies
Color: Stick
I have puppies that are 6 weeks old and this toy has been great. They like to gnaw on it as their teeth are erupting. I easy to clean, washer and dryer. I have several other teething toys from same company as I liked this one so much. Would purchase again, highly recommend for teething pups.
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Reviewed in the United States on January 6, 2024
C
Verified Purchase
Chill39
Belleville, US
★★★★★ 5
My English springer spaniels favorite toy!
Color: Stick, Color: Stick
Boomer, my English springer spaniel loves this toy, it is by far his favorite since he was a young puppy. He is three now and although the original toy is still useable it was showing a little wear so I purchased a second one for his third birthday. He was an aggressive chewer when he was younger and I had a great deal of difficulty in finding toys he would not destroy in 30 minutes. I bought the Orka stick to help with teething and it proved to be very durable and became his favorite toy. He loves the new one just as much enthusiasm. boomer doesn't like the rope so I removed it.
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Reviewed in the United States on May 18, 2015
L
Verified Purchase
labsrule72
New York, US
★★★★★ 2
Disappointment
Color: Stick
Disappointment, I have bought these for several of my labs as pups in the past, The center material used to be fleece with knots at ends and difficult To pull through the rubber chew . This toy now has like cotton and polyester strings through the toy tied into knots it easily to chews a part with the dogs, sticks in their teeth and makes a mess, Also easily pulls right through out of the rubber chew toy . After less than one day I ended up throwing away this knotted ball of string and I threaded some fleece strips through the toy and made large nots at the ends, it is now holding up quite well To a pretty aggressive puppy chewer. But I pretty much had to make my own toy
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Reviewed in the United States on September 11, 2022
K
Verified Purchase
Kelly
Battle Creek, US
★★★★★ 4
Good for adult & puppy.
We have a one year old English Mastiff female & a 3 month old English Mastiff male puppy. They both love this toy. I have to say Pet Stages won me over after my mother gave me a few of their toys. I'm not a fan of bright colors, but the dogs just these things. All the toys seem to be designed & tested to keep them interested. My dogs love trying to pull the ropes out, chewing the blue firm but soft enough tube and playing tug-o-war with it.
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Reviewed in the United States on December 8, 2009

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