SKU: 9027006019

MUC1/EMA Mouse mAb,PBS Only (SDT-777-37)

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Description

MUC1/EMA Mouse mAb,PBS Only (SDT-777-37)Product Specification Host Mouse Antigen MUC1 Synonyms Mucin 1, MUC 1, Breast carcinoma associated antigen DF3, Cancer antigen 15 3 (CA 15 3), Carcinoma associated mucin, Episialin, H23AG, Krebs von den Lungen 6 (KL 6), PEMT, Peanut reactive urinary mucin (PUM), Polymorphic epithelial mucin (PEM), Tumor associated epithelial membrane antigen (EMA), Tumor associated mucin Immunogen Synthetic Peptide Location Cytoplasm, Cell membrane Accession P15941

Product Specification


Host Mouse
Antigen MUC1
Synonyms Mucin-1, MUC-1, Breast carcinoma-associated antigen DF3, Cancer antigen 15-3 (CA 15-3), Carcinoma-associated mucin, Episialin, H23AG, Krebs von den Lungen-6 (KL-6), PEMT, Peanut-reactive urinary mucin (PUM), Polymorphic epithelial mucin (PEM), Tumor-associated epithelial membrane antigen (EMA), Tumor-associated mucin
Immunogen Synthetic Peptide
Location Cytoplasm, Cell membrane
Accession P15941
Clone Number SDT-777-37
Antibody Type Mouse mAb
Isotype IgG1,k
Application WB, IHC-P, ICC, IP, IF, ICFCM
Reactivity Hu, Rt
Purification Protein G
Concentration 2 mg/ml
Conjugation Unconjugated
Physical Appearance Liquid
Storage Buffer

PBS

Stability & Storage

12 months from date of receipt / reconstitution, 4°C as supplied

Dilution


application dilution species
WB 1:1000
IP 1:200
IHC-P 1:500-1:2000
ICC 1:500
ICFCM 1:2000
IF 1:500

Background

MUC1 is a transmembrane protein normally expressed in glandular or luminal epithelial cells and hematopoietic cells and absent in skin epithelium and mesenchymal cells. Apical surface of almost all glandular and ductal epithelial cells, including respiratory, gastrointestinal, urogenital, hepatobiliary tracts, sebaceous and salivary glands. MUC1 is expressed in the central cells of pancreatic acini, intercalary duct epithelium, and interlobular duct epithelium, but not in the acinar epithelium, main pancreatic duct epithelium, and pancreatic islet epithelium. Overexpression is common in malignancies and leads to tumorigenesis. Increased expression is associated with poor prognosis of most carcinomas, including those involving breast, cervical, pancreatic, colorectal.

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Exchange/Return Notes
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SKU: 9027006019

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