SKU: 92498050966

Alexa Fluor 647-Labeled CD38 Fc Chimera Protein, Human

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Description

Alexa Fluor 647-Labeled CD38 Fc Chimera Protein, HumanProduct Specification Species Human Synonyms ADPRC1,cADPR1,ADPRC 1 Accession P28907 1 Amino Acid Sequence Val43 Ile300 with Human IgG1 Fc at C terminal Expression System HEK293 Molecular Weight 68 72kDa (Reducing) Conjugation Alexa Fluor 647 Physical Appearance Liquid Storage Buffer PBS, pH7. 4 Stability & Storage 12 months from date of receipt, lyophilized powder stored at 20 to 80. 3 months, 20 to 80 under sterile conditions after reconstitution. 1

Product Specification


Species Human
Synonyms ADPRC1,cADPR1,ADPRC 1
Accession P28907-1
Amino Acid Sequence

Val43-Ile300 with Human IgG1 Fc at C-terminal
Expression System HEK293
Molecular Weight

68-72kDa (Reducing)
Conjugation Alexa Fluor® 647
Physical Appearance Liquid
Storage Buffer

PBS, pH7.4
Stability & Storage

· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.
Reference

1.Matas-Céspedes A, Vidal-Crespo A, Rodriguez V, Villamor N, Delgado J, Giné E, Roca-Ho H, Menéndez P, Campo E, López-Guillermo A, Colomer D, Roué G, Wiestner A, Parren PW, Doshi P, van Bueren JL, Pérez-Galán P. The Human CD38 Monoclonal Antibody Daratumumab Shows Antitumor Activity and Hampers Leukemia-Microenvironment Interactions in Chronic Lymphocytic Leukemia. Clin Cancer Res. 2017 Mar 15;23(6):1493-1505.
2.Lokhorst HM, Plesner T, Laubach JP, Nahi H, Gimsing P, Hansson M, Minnema MC, Lassen U, Krejcik J, Palumbo A, van de Donk NW, Ahmadi T, Khan I, Uhlar CM, Wang J, Sasser AK, Losic N, Lisby S, Basse L, Brun N, Richardson PG. Targeting CD38 with Daratumumab Monotherapy in Multiple Myeloma. N Engl J Med. 2015 Sep 24;373(13):1207-19.

Background

Daratumumab is a first-in-class Homo sapiens monoclonal antibody of the IgG1 class, specifically targeting the human CD38 protein. It binds to CD38, triggering apoptosis via mechanisms of antibody-dependent cellular cytotoxicity (ADCC) and complement-dependent cytotoxicity (CDC). This antibody is applicable for research related to hematoma, suitable for use in both human and immunodeficient mouse models. Studies have indicated that Daratumumab also exerts influence on the survivability and transmission of chronic lymphocytic leukemia (CLL), particularly in cases characterized by poor prognosis and high CD38 expression.

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Exchange/Return Notes
  • We offer a 30-day return/exchange service after receiving.
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  • To process your return/exchange, please contact us at [email protected]
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SKU: 92498050966

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4.4 ★★★★★
Based on 16 reviews
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Product Reviews
M
Verified Purchase
Mother of two
Waukegan, US
★★★★★ 5
Precious toy for big dogs too
Size: Large, Color: Skinny Green
Not only is this toy cute and fun, but material is thick and durable even for my crazy GSP who is a destruction artist. This is, the favorite toy his go to in the toy box.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 15, 2026
V
Verified Purchase
VanillaPepper
Massapequa, US
★★★★★ 5
Indestructible Toys My Dobermans ❤️
Size: Large, Color: Mesh Green
Actually Respect! goDog Is a Lifesaver The variety of size and colors are phenomenal 😇 I have two Dobermans — serious, determined power chewers — and I’ve spent years trying to find toys that survive even a few days. I’ve tried the big brands (Kong, Goughnuts, Jolly Ball, you name it) — and while some toys last a little while, almost everything eventually ends up shredded, de-squeaked, or in pieces. goDog toys are the ONLY plush toys my Dobermans won’t destroy. We own multiple goDog toys now — dragons, dinosaurs, lizards — mostly in the large size (perfect for Dobermans), but even a few medium-sized ones hold up surprisingly well. Here’s what’s amazing: • They love them — actually carry them around, toss them, chew them gently, and squeak them happily. • They do not rip them apart — no matter how much tugging, chewing, or wrestling happens. • Large sizes are best for Dobermans (and other big breeds) — but even mediums survive for calmer play sessions. • No ripped seams, no stuffing everywhere, and no destroyed squeakers after months of use. What makes goDog toys different? The secret is their Chew Guard Technology — • A reinforced, high-strength inner mesh layer under the soft plush • Double-stitched seams • Durable yet flexible material that somehow resists punctures, tears, and brutal shaking The outside stays soft and fun, but the inside is built like armor. It’s NOT a super hard rubber or rough canvas — it still feels like a cuddle toy, but it’s engineered to survive serious chewing. Materials include: • Durable polyester plush • Chew Guard inner lining (high-tensile mesh fabric) • Reinforced stitching • Non-toxic squeakers • Safe for dogs to play with long-term Real Owner Advice: • Always size up if you have a heavy chewer — large sizes are a must for Dobermans or similarly strong breeds. • Medium sizes are fine if you supervise or your dog is more moderate with toys, but the large toys are built tougher overall. Final Thoughts: If you have big dogs, strong jaws, or just tired of wasting money on destroyed toys — goDog toys are a must. No other plush-style toy even comes close. My Dobermans will destroy almost anything… but they treat their goDog toys like treasured companions. No holes, no rips, just happy dogs. Follow me here on Amazon for more honest, dog-tested reviews! Like this review if it helped — I’ll be uploading even more proven tough toys and pet essentials soon!
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on April 29, 2025
B
Verified Purchase
BB
New York, US
★★★★★ 4
Surface Fabric is very durable
Size: Small, Color: Hot Pink
Surface Fabric is very durable, but the squeaker didn't last two months. I have urged the manufacturer to find a strong more durable squeaker for their product. My dogs really enoys it when the speaker works. One of his 3 work. I have just bought two more he likes them so much. He takes it to bed every night to catch it once or twice before sleeping. Also loves to catch it a few times during the day.
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Reviewed in the United States on April 11, 2026
T
Verified Purchase
Taraknits
Draper, US
★★★★★ 5
Best. Toy. Ever. For My Superchewer!
Size: Large, Color: Skinny Green, Size: Large, Color: Skinny Green
Best toy ever! My dog destroys toys. Usually within about 15 minutes, she has de-squeakered and defluffed them. By the second day, she has tug-of-war-ed them to shreds. From the time we got this adorable dragon out of the package, she LOVED it. She set to work. It’s been a week, and while she has dewinged him, he lost his squeaker after a few days, and he looks a bit rough, he’s still in one piece! And, we’ve had HOURS of tug-of-war with minimal rips! She’s obsessed 😍 I ordered two more today. We’ve finally found the perfect toy for my baby!
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on January 18, 2026
S
Verified Purchase
SnowshoePete
Whiting, US
★★★★★ 5
My 90 lb. Pitbull's All-Time Fave Toy
Size: Large, Color: Coral, Size: Large, Color: Coral
I ordered a plethora of new toys for Bruce to keep him occupied while I am working remotely from home. Poor guy gets so bored while I'm stuck in front of my computer 8+ hours a day. All the other toys are animated, but this one is just a big floppy chewy squeaky toy. Bruce quickly lost interest in all the other chirping, hopping, and twirling toys and fell in love with "Diny". When I opened Diny and gave it to Bruce, he had the elated and surprised look of a 3 yr old at Christmas. And he stayed that happy for hours, and then each time he picked up Diny to play. Diny became his go-to toy over all others (and there are many!). It is well made out of durable fabric, and they did not stuff it full of kapoc (I hate kapoc in dogs toys!). And it is delightfully low-tech. Normally he tears a squeaky toy apart as soon as he can isolate the squeaky mechanism. But cleverly, the squeaky box is loose in the long belly so it moves from one end to the other as the toy is handled. That made it difficult for Bruce to locate it. The toy remained in good condition for 2 weeks of near constant attention by Bruce. But yesterday he zeroed in on the squeaky box and ripped Diny to shreds. I was sad to see Diny go so soon. But boy-howdy was Bruce happy with it. I'm gonna buy another because we liked it so much. And so did I : )
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 23, 2024

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