SKU: 93097838009

LONP1 Rabbit Polyclonal Antibody

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Description

LONP1 Rabbit Polyclonal AntibodyProduct Specification Host Rabbit Antigen LONP1 Synonyms Lon protease homolog, mitochondrial; LONHs; Lon protease like protein (LONP); Mitochondrial ATP dependent protease Lon; Serine protease 15; PRSS15 Immunogen Synthetic Peptide Location Mitochondrion Accession P36776 Antibody Type Polyclonal antibody Isotype IgG Application WB, IHC P Reactivity Hu, Ms, Rt Positive Sample HEK 293, HeLa, SH SY5Y, Jurkat, NIH 3T3, C6 Predicted Reactivity Bv

Product Specification


Host Rabbit
Antigen LONP1
Synonyms Lon protease homolog, mitochondrial; LONHs; Lon protease-like protein (LONP); Mitochondrial ATP-dependent protease Lon; Serine protease 15; PRSS15
Immunogen Synthetic Peptide
Location Mitochondrion
Accession P36776
Antibody Type Polyclonal antibody
Isotype IgG
Application WB, IHC-P
Reactivity Hu, Ms, Rt
Positive Sample HEK-293, HeLa, SH-SY5Y, Jurkat, NIH/3T3, C6
Predicted Reactivity Bv
Purification Immunogen Affinity
Concentration 2 mg/ml
Conjugation Unconjugated
Physical Appearance Liquid
Storage Buffer

PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300

Stability & Storage

12 months from date of receipt / reconstitution, -20 °C as supplied

Dilution


application dilution species
WB 1:1000 Hu, Ms, Rt
IHC-P 1:500 Hu, Ms, Rt

Background

LONP1 protein, also known as Lon protease homolog 1, is a nuclear-encoded mitochondrial AAA+ serine protease that plays a crucial role in maintaining mitochondrial homeostasis. It is highly conserved across species and is composed of three functional domains: an N-terminal domain for substrate recognition, an AAA+ domain for ATP binding and hydrolysis, and a protease domain for protein degradation. LONP1 forms a hexameric complex in the mitochondrial matrix and is responsible for degrading misfolded, oxidized, and damaged proteins to prevent their accumulation and maintain mitochondrial proteostasis. Additionally, LONP1 has chaperone-like functions in protein folding and assembly, and it regulates mitochondrial DNA (mtDNA) replication and transcription by interacting with mitochondrial transcription factor A (TFAM). Its dysfunction is associated with various diseases, including mitochondrial disorders and cancer, making it a potential target for therapeutic interventions.

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SKU: 93097838009

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Jen
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★★★★★ 5
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My son loves his monitor. It has great graphics , he games on it all the time and has no complaints. He loves the curve on it to.
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Reviewed in the United States on March 29, 2026
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wyldfyre1
Battle Creek, US
★★★★★ 5
Glad i got it.
Style: 2026 Curved 24" 180Hz
I've been needing a new monitor and ended up settling for this one after looking a bit online. Was VERY happy with how easy it was to setup the picture quality is amazing and quality as a whole is very good! Games look good on it! It was a good buy.
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Reviewed in the United States on May 3, 2026
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Cassandra
San Leandro, US
★★★★★ 5
Love it
Style: 2026 Curved 24" 180Hz
Absolutely love this TV! The picture is crystal clear, colors are vibrant, and the sound is surprisingly powerful. Setup was quick and easy, and streaming apps run smoothly with no lag. It completely upgraded my movie nights—great value for the price! Highly recommend!
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Reviewed in the United States on March 3, 2026
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Rachel
Natrona Heights, US
★★★★★ 5
Good monitor
Style: 2026 Curved 24" 180Hz
Not much to say other than good monitor. The resolution is clear and for my situation of 3d modeling it's more than enough. Idk about heavy gaming but I haven't had any issues with frame rates or image quality. Overall seems like a nice quality monitor and plan to probably upgrade to a 34" one by this brand and have the 24" monitor as a second screen
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Reviewed in the United States on June 2, 2026
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Ioane Kadagidze
Phoenix, US
★★★★★ 5
The monitor is awesome for the price
Style: 2026 Curved 24" 180Hz
Great monitor for it’s price, loving it.
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