SKU: 93723731392

RSPO2 C-Flag Protein,Human

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Description

RSPO2 C-Flag Protein,HumanProduct Specification Species Human Synonyms R spondin 2; RSPO2; Roof plate specific spondin 2; hRspo2; PRO34209 Accession Q6UXX9 Amino Acid Sequence Gln22 Gly205, with a Flag tag at the C terminus Expression System CHO Molecular Weight 22. 3 KDa Purity 95% by SDS PAGE Physical Appearance Lyophilized Powder Storage Buffer Lyophilized from a 0. 2 m filtered solution of PBS, pH7. 4. Reconstitution Always centrifuge tubes before opening. Do not mix by

Product Specification


Species Human
Synonyms R-spondin-2; RSPO2; Roof plate-specific spondin-2; hRspo2; PRO34209
Accession Q6UXX9
Amino Acid Sequence

Gln22-Gly205, with a Flag tag at the C-terminus

Expression System CHO
Molecular Weight

22.3 KDa
Purity

＞95% by SDS-PAGE
Physical Appearance Lyophilized Powder
Storage Buffer

Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
Reconstitution

Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Stability & Storage
  • Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt.
  • Reconstituted protein solution can be stored at 2-8°C for 2-7 days.
  • Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

Background

R-spondin-2, also known as RSPO2, synergizes with Wnt to activate beta-catenin. R-spondins are a family of four matricellular proteins produced by a variety of cell-types. The four R spondin secreted ligands (RSPO1–RSPO4) act via their cognate LGR4, LGR5 and LGR6 receptors to amplify WNT signalling. Rspo2 in FGF pathway regulation in vivo Overexpressed Rspo2 inhibited elongation of Xenopus ectoderm explants and Erk1 activation in response to FGF. R-spondin2 (RSPO2) plays a crucial role in the activation of the WNT/β-catenin pathway and oncogenesis, RSPO2 in GC specimens and cell lines is closely related to tumor invasion and migration and that RSPO2 promotes EMT in gastric cancer cells by activating WNT/β-catenin signaling.

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SKU: 93723731392

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4.7 ★★★★★
Based on 9 reviews
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Product Reviews
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Verified Purchase
Darice11
Battle Creek, US
★★★★★ 3
Good not excellent
This book started off with lots of promise. It got my interest straight away and kept it there for a few chapters. It includes some intesting history facts of the age and enlists some of the characters of the age as well all of which I found very intersting and unique. However the general theme did not change. The Protaganist got better and better at killing and never really got into trouble. He goes from one adventure to another of similar sort with the same outcome. He kills everyone and gets away without problems. I had trouble finding the climax and wondered at many points if it was just a story that went on and on without an end. Overall a good light read if you don't expect much surprise or complex intrigue.
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Reviewed in the United States on August 5, 2012
A
Verified Purchase
Amazon Customer
Battle Creek, US
★★★★★ 5
I loved this book!!!
Format: Kindle
I had just started play AC but when I saw the books I got really excited! It was very good, it kept you on your toes!!
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Reviewed in the United States on May 24, 2024
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Verified Purchase
Ayamuri
Lowell, US
★★★★★ 4
Neither bad nor terrific. A rehash of AC 2
Format: Kindle
I purchased the book hoping it would be something completely new with Ezio, a unique story told by the author that was unrelated to the series. Sadly, it wasn't. This book was great in refreshing much of what happens in Assassin's Creed 2 and some of the memory assignments you can do in Brotherhood (and perhaps Revelations too, though at the time of writing this review, I've only barely dug into Revelations). But because I knew what to expect, I wasn't sitting on the edge of my seat to read it. The one tidbit I didn't like was that it seemed the author sometimes used too many commas. It's minor, but I frequently had to re-read some sentences to ensure it wasn't a run-on. I do like that there's a glossary in the back for the Italian that's frequently sprinkled in. All in all, if you've not played Assassins Creed 2, this would be great for quickly getting caught up (though I'd recommend the game instead for the visual/aural experience) or if you need a refresher. Otherwise, this might be a bit dull since you'll know what to expect.
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Reviewed in the United States on April 20, 2013
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Verified Purchase
Samuel Hayes
Fort Morgan, US
★★★★★ 5
better than the game
Format: Kindle
Assassins Creed Renaissance is a fantastic read whether you have played the game or not. It follows the story of assassins creed 2 to the letter but also adds more story elements that help answer some of the games little questions that were left unanswered. It is also a great read for anyone who hasn't played the game as it requires no prior knowledge of the assassins creed universe. I highly recommend this book to anyone who wants a more in depth look at the game or anyone who just wants a good book to read.
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Reviewed in the United States on July 24, 2016
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DennisIGuess
Natrona Heights, US
★★★★★ 5
Art book
Format: Hardcover
Had to buy the art book after rewatching the show! The quality is great!
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on January 18, 2026

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