SKU: 9501315996

Human Thyroid peroxidase Protein, His Tag

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Description

Human Thyroid peroxidase Protein, His TagProduct Specification Species Human Synonyms TPO Accession P07202 Amino Acid Sequence Protein sequence (P07202, Phe19 Arg846, with C His Tag)

Product Specification


Species Human
Synonyms TPO
Accession P07202
Amino Acid Sequence

Protein sequence (P07202, Phe19-Arg846, with C-His Tag) FFPFISRGKELLWGKPEESRVSSVLEESKRLVDTAMYATMQRNLKKRGILSPAQLLSFSKLPEPTSGVIARAAEIMETSIQAMKRKVNLKTQQSQHPTDALSEDLLSIIANMSGCLPYMLPPKCPNTCLANKYRPITGACNNRDHPRWGASNTALARWLPPVYEDGFSQPRGWNPGFLYNGFPLPPVREVTRHVIQVSNEVVTDDDRYSDLLMAWGQYIDHDIAFTPQSTSKAAFGGGADCQMTCENQNPCFPIQLPEEARPAAGTACLPFYRSSAACGTGDQGALFGNLSTANPRQQMNGLTSFLDASTVYGSSPALERQLRNWTSAEGLLRVHARLRDSGRAYLPFVPPRAPAACAPEPGIPGETRGPCFLAGDGRASEVPSLTALHTLWLREHNRLAAALKALNAHWSADAVYQEARKVVGALHQIITLRDYIPRILGPEAFQQYVGPYEGYDSTANPTVSNVFSTAAFRFGHATIHPLVRRLDASFQEHPDLPGLWLHQAFFSPWTLLRGGGLDPLIRGLLARPAKLQVQDQLMNEELTERLFVLSNSSTLDLASINLQRGRDHGLPGYNEWREFCGLPRLETPADLSTAIASRSVADKILDLYKHPDNIDVWLGGLAENFLPRARTGPLFACLIGKQMKALRDGDWFWWENSHVFTDAQRRELEKHSLSRVICDNTGLTRVPMDAFQVGKFPEDFESCDSITGMNLEAWRETFPQDDKCGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLTCTQEGWDFQPPLCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVDSGRLPR
Expression System HEK293
Molecular Weight Predicted MW: 93.7 kDa Observed MW: 110 kDa
Purity ＞95% by SDS-PAGE
Endotoxin <1EU/μg
Conjugation Unconjugated
Physical Appearance Lyophilized powder
Storage Buffer

Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, pH7.4 with 3% trehalose.
Reconstitution Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation.
Stability & Storage

12 months from date of receipt, -20 to -70 °C as supplied.
6 months, -20 to -70 °C under sterile conditions after reconstitution.
1 week, 2 to 8 °C under sterile conditions after reconstitution.
Please avoid repeated freeze-thaw cycles.

Background

Thyroid peroxidase, also called thyroperoxidase (TPO) or iodide peroxidase, is an enzyme expressed mainly in the thyroid where it is secreted into colloid. Thyroid peroxidase oxidizes iodide ions to form iodine atoms for addition onto tyrosine residues on thyroglobulin for the production of thyroxine (T4) or triiodothyronine (T3), the thyroid hormones. In diagnostic immunohistochemistry, the expression of thyroid peroxidase (TPO) is lost in papillary thyroid carcinoma. Thyroid peroxidase is also a frequent epitope of autoantibodies in autoimmune thyroid disease, with such antibodies being called anti-thyroid peroxidase antibodies (anti-TPO antibodies). This is most commonly associated with Hashimoto's thyroiditis. Thus, an antibody titer can be used to assess disease activity in patients that have developed such antibodies.

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SKU: 9501315996

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4.5 ★★★★★
Based on 12 reviews
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Verified Purchase
H. Glezos
Dallas, US
★★★★★ 5
Best way for hot chocolate
Color: Black
works great, I use it for hot chocolate. Easy to clean. Something to consider though the Max light may be a little lower than shown depending on the milk you use.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 17, 2026
E
Verified Purchase
Elizabeth Cook
Whiting, US
★★★★★ 2
Check your milk preference when buying this unit. Product Does not last
Color: White
I purchased this frother in mid Oct and less than 90 days later, it's no longer working. The wisk does not spin, and the element does not heat the milk. I am currently working with customer support on a refund / replacement, but so far not happy. I've been told it does not work with 2% organic milk and that I need to switch to whole milk, which will solve my issues. Not sure how whole milk will help with the heating element? This was not disclosed when I purchased the unit. If I had known my milk choice would impact the frother, I would have chosen another brand or product. I like the unit, it's compact, easy to clean, but it did not last.
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Reviewed in the United States on January 12, 2026
M
Verified Purchase
M. Miski
Lake Worth, US
★★★★★ 5
Easy to use, reliable machine
Color: White
Great product! I have a fully automated DeLonghi cappuccino/latte coffee machine. After 5 years of use, the machine's milk frothing function started to fail. I purchased this product to supplement/replace the milk frother on my DeLonghi automated coffee machine; it works great and produces copious milk froth with much less mess.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on March 18, 2026
S
Verified Purchase
Stephanie R.
Louisville, US
★★★★★ 5
Best frother ever!
Color: White
This is the best frother ever! Works better than my expensive espresso machine frother. So easy and makes a large amount enough for 2 large cappuccinos.
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Reviewed in the United States on April 21, 2026
A
Verified Purchase
Amazon Customer
Phoenix, US
★★★★★ 1
False advertising--it won't froth almond milk.
Color: White
Bought this because I am vegetarian and I've consumed Almond milk for the past 15 years. The profile on this product said it would froth all milks, including almond. It does not--it heats the almond milk but does not froth it. It did froth 2% cow's milk I served a visitor, but I won't use cow's milk. I missed the return date by 1 day, or it would have been returned this product for a full refund. If you want to froth plant/ nut milk, don't waste your $$$.
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Reviewed in the United States on May 9, 2026

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