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Description
GLUT-1 Recombinant Rabbit mAb (Alexa Fluor® 488 Conjugate) (SDT-047-53)Product Specification Host Rabbit Antigen GLUT 1 Synonyms SLC2A1, GLUT1 Immunogen Synthetic Peptide Location Cell membrane, Melanosome Accession P11166 Clone Number SDT 047 53 Antibody Type Recombinant mAb Application ICC, ICFCM Reactivity Hu Purification Protein A Concentration 2 mg ml Conjugation Alexa Fluor 488 Physical Appearance Liquid Storage Buffer PBS, 0. 1% BSA, 0. 01% Proclin 300 Stability & Storage 12 months from date of receipt
Product Specification
| Host | Rabbit |
| Antigen | GLUT-1 |
| Synonyms | SLC2A1, GLUT1 |
| Immunogen | Synthetic Peptide |
| Location | Cell membrane, Melanosome |
| Accession | P11166 |
| Clone Number | SDT-047-53 |
| Antibody Type | Recombinant mAb |
| Application | ICC, ICFCM |
| Reactivity | Hu |
| Purification | Protein A |
| Concentration | 2 mg/ml |
| Conjugation | Alexa Fluor® 488 |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 0.1% BSA, 0.01% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied. |
Dilution
| application | dilution | species |
| ICC | 1:500 | null |
| ICFCM | 1:200 | null |
Background
Glucose enters cells through various transporters including the GLUT family of facilitative transporters, the sodium/glucose co-transporters, and the recently discovered SWEET family. however, only the role of the GLUT family has been extensively studied in cancer cells. There are 14 GLUT proteins in the human and 12 in the mouse. GLUT1, encoded by SLC2A1, is the predominant transporter overexpressed in tumors, including hepatic, pancreatic, esophageal, brain, renal, lung, cutaneous, colorectal, endometrial, ovarian, cervical, and breast, as well as head and neck tumors.
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