SKU: 95698644076

Alexa Fluor® 488 Rabbit Anti-Mouse NK1.1/CD161 Antibody (S-428-32)

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Description

Alexa Fluor® 488 Rabbit Anti-Mouse NK1.1/CD161 Antibody (S-428-32)Product Specification Host Rabbit Antigen NK1. 1 CD161 Synonyms Killer cell lectin like receptor subfamily B member 1C; CD161 antigen like family member C; Lymphocyte antigen 55c (Ly 55c); NK1. 1; NKR P1. 9; NKR P1C; Natural killer cell surface protein P1 40 (NKR P1 40); CD161c; Ly55c; Nkrp1c; Klrb1c Immunogen Recombinant Protein Location Membrane Accession P27814 Clone Number S 428 32 Antibody Type Recombinant mAb Isotype IgG Application FCM

Product Specification


Host Rabbit
Antigen NK1.1/CD161
Synonyms Killer cell lectin-like receptor subfamily B member 1C; CD161 antigen-like family member C; Lymphocyte antigen 55c (Ly-55c); NK1.1; NKR-P1.9; NKR-P1C; Natural killer cell surface protein P1-40 (NKR-P1 40); CD161c; Ly55c; Nkrp1c; Klrb1c
Immunogen Recombinant Protein
Location Membrane
Accession P27814
Clone Number S-428-32
Antibody Type Recombinant mAb
Isotype IgG
Application FCM
Reactivity Ms
Positive Sample C57BL/6 mouse splenocytes
Purification Protein A
Concentration 0.05mg/ml
Conjugation Alexa Fluor® 488
Physical Appearance Liquid
Storage Buffer

PBS, 25% Glycerol, 1% BSA, 0.3% Proclin 300

Stability & Storage 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied.

Dilution


application dilution species
FCM 5μl per million cells in 100μl volume Ms

Background

NK1.1/CD161, also known as KLRB1, is a receptor protein expressed on the surface of natural killer (NK) cells and certain T cells. In mice, NK1.1 belongs to the NKRP1 receptor family and interacts with C-type lectin-related molecules, playing a role in immune recognition and regulation. In humans, CD161 on NK cells interacts with ligands such as LLT1, and this interaction is inhibitory, helping to regulate NK cell function. Additionally, CD161 is involved in intracellular signaling pathways, such as the AKT pathway, which influences NK cell activity. This protein is also a marker for different subsets of NK cells, with high expression in certain mature and cytotoxic NK cell populations.

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Exchange/Return Notes
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SKU: 95698644076

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4.7 ★★★★★
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Today
Carnegie, US
★★★★★ 5
Airedale tough!
Color: Rubber Chew Toy, Size: Large
We have two young Airedale Terriers and I thought this would be a good inside toy for them to tug. And I was right! Very happily so. I have to admit I was surprised when I first saw it; it seemed so small. But the thing stretches and springs back to shape. We’ve had it about 2 weeks now and it is constantly played with. Absolutely the best toy! Very interactive either alone (it rolls) or with us or they play together. I am surprised how tough it is with all the constant rough play. Highly recommend!!!
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Reviewed in the United States on May 12, 2022
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Julie
Chelsea, US
★★★★★ 4
Small, but twisty and fun looking. Seems relatively sturdy, though doesn't look indestructible at all.
Color: Rubber Chew Toy, Size: Large
SLIGHTLY disappointed because I thought this was bigger than it is. If you squish it all in close, it's maybe one and a half times the size of a tennis ball. (Of course, the size is probably listed; I think I just assumed, so my fault.) That being said, it's entertainingly twisty and squishy, though the rubber seems relatively sturdy. I'm not yet positive if it will hold up to the 8 month retriever/lab mix it's intended for; he tends to rip instantly through anything much less sturdy than kong natural rubber. But it seems like something that will amuse him, so we're going to give it a shot at Christmas.
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Reviewed in the United States on November 7, 2014
K
Verified Purchase
Kindle Customer
Los Angeles, US
★★★★★ 5
Great product!
Color: Rubber Chew Toy, Size: Large
My dog is an aggressive chewer. I have bought this 3 times for her she loves to play tug and fetch with it. They last longer than most of the other toys I get her and it’s one of her favorites.
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Reviewed in the United States on January 1, 2025
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Kate
Port Orchard, US
★★★★★ 3
It’s okay I guess
Color: Rubber Chew Toy, Size: Large
Good price and decent toy, seems well made. My puppy is entirely uninterested and doesn’t play with it at all.
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Reviewed in the United States on April 23, 2026
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PattyJoyce on Joe List
Whiting, US
★★★★★ 1
Very dangerous for chewers!!!
Color: Rubber Chew Toy, Size: Large
My dog was chewing/swallowing the hard rubber within seconds of having this "toy"!!! Not safe, sturdy, no play attraction; only desire was to consume!!!
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Reviewed in the United States on March 16, 2026

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