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Description
Asialoglycoprotein Receptor 1 Recombinant Rabbit mAb (SDT-292-48)Product Specification Host Rabbit Antigen Asialoglycoprotein Receptor 1 Synonyms ASGP R 1, ASGPR 1, C type lectin domain family 4 member H1, Hepatic lectin H1, HL 1, ASGR1, CLEC4H1 Immunogen Recombinant Protein Location Secreted, Membrane Accession P07306 Clone Number SDT 292 48 Antibody Type Recombinant mAb Application WB, IHC P, ICC, ICFCM Reactivity Hu, Ms, Rt Purification Protein A Concentration 0. 5 mg ml Physical Appearance Liquid Storage Buffer
Product Specification
| Host | Rabbit |
| Antigen | Asialoglycoprotein Receptor 1 |
| Synonyms | ASGP-R 1, ASGPR 1, C-type lectin domain family 4 member H1, Hepatic lectin H1, HL-1, ASGR1, CLEC4H1 |
| Immunogen | Recombinant Protein |
| Location | Secreted, Membrane |
| Accession | P07306 |
| Clone Number | SDT-292-48 |
| Antibody Type | Recombinant mAb |
| Application | WB, IHC-P, ICC, ICFCM |
| Reactivity | Hu, Ms, Rt |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000-1:5000 | null |
| IHC-P | 1:2000 | null |
| ICFCM | 1:5000 | null |
| ICC | 1:500 | null |
Background
Asialoglycoprotein receptors (ASGP-R; exist as subtypes 1 and 2) are located on the surface of hepatic cell membranes and are involved in the binding and endocytosis of glycoproteins that have exposed carbohydrate or N-acetylgalactosamine residues. In addition, the decreased level of ASGP-R on the hepatic cells has been shown to correlate clinically with the degree of liver function retained due to the development of cirrhosis, cancer, or viral hepatitis [PMID: 20641215].
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