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Description
PCBP4 Recombinant Rabbit mAb (S-3107-175)Product Specification Host Rabbit Antigen PCBP4 Synonyms Poly(rC) binding protein 4 Immunogen Synthetic Peptide Location Cytoplasm Accession P57723 Clone Number S 3107 175 Antibody Type Recombinant mAb Isotype IgG Application WB Reactivity Hu, Ms, Rt, Mk Positive Sample HeLa, NIH 3T3, PC 12, COS 7 Purification Protein A Concentration 2 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS, 40% Glycerol, 0. 05% BSA, 0. 03%
Product Specification
| Host | Rabbit |
| Antigen | PCBP4 |
| Synonyms | Poly(rC)-binding protein 4 |
| Immunogen | Synthetic Peptide |
| Location | Cytoplasm |
| Accession | P57723 |
| Clone Number | S-3107-175 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB |
| Reactivity | Hu, Ms, Rt, Mk |
| Positive Sample | HeLa, NIH/3T3, PC-12, COS-7 |
| Purification | Protein A |
| Concentration | 2 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | Hu, Ms, Rt, Mk |
Background
PCBP4 (Poly(rC) Binding Protein 4), also known as MCG10 or hnRNP E4, is an RNA-binding protein belonging to the hnRNP K homology domain-containing family. It regulates mRNA stability, translation, and alternative splicing by binding to poly(C) motifs in target transcripts. PCBP4 plays critical roles in cellular stress responses, cell cycle arrest, and apoptosis through post-transcriptional control of genes involved in proliferation and DNA damage response. Its expression is frequently downregulated in various cancers, functioning as a tumor suppressor by stabilizing mRNAs encoding cell cycle inhibitors and pro-apoptotic factors.
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