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Description
NCAM-1/CD56 (ΔQ609, G610R, M621R) His Tag Protein, HumanProduct Specification Species Human Synonyms Neural cell adhesion molecule 1,CD56,NCAM1,NCAM,Neural Cell Adhesion Molecule,NCAM,CD56 Antigen,N CAM 1,MSK39,NCAM 1,Antigen Recognized By Monoclonal Antibody 5. 1H11 Accession P13591 2 Amino Acid Sequence Leu20 Gly718 (Q609, Gly610Arg, Met621Arg) with His Tag at C Terminus Expression System HEK293 Molecular Weight 90 110kDa (Reducing) Purity >95% as determined by SDS PAGE & SEC HPLC Endotoxin <0. 1EU g
Product Specification
| Species | Human |
| Synonyms | Neural cell adhesion molecule 1,CD56,NCAM1,NCAM,Neural Cell Adhesion Molecule,NCAM,CD56 Antigen,N-CAM-1,MSK39,NCAM-1,Antigen Recognized By Monoclonal Antibody 5.1H11 |
| Accession | P13591-2 |
| Amino Acid Sequence | Leu20-Gly718 (ΔQ609, Gly610Arg, Met621Arg) with His Tag at C-Terminus |
| Expression System | HEK293 |
| Molecular Weight | 90-110kDa (Reducing) |
| Purity | >95% as determined by SDS-PAGE & SEC-HPLC |
| Endotoxin | <0.1EU/μg |
| Conjugation | Unconjugated |
| Tag | His Tag |
| Physical Appearance | Lyophilized powder |
| Storage Buffer | PBS, PH7.4, 5% trehalose |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. |
| Reference | 1.Guven A. et al. (2021) Development and validation of an immunoassay for quantification of NCAM-1 in human plasma. Journal of Pharmaceutical and Biomedical Analysis. 197: 113981. |
Background
Neural Cell Adhesion Molecule 1 (NCAM-1), a multifunctional member of the immunoglobulin superfamily, is expressed on neurons, glia, skeletal muscle, and natural killer cells. It plays a key role in cell-cell adhesion and is crucial for nervous system development. Additionally, NCAM-1 is involved in the expansion of T cells and dendritic cells, which are vital for immune surveillance.
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