SKU: 6087596396

GW-0742 Solution, 600MG (20mg/mL)

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Description

GW-0742 Solution, 600MG (20mg/mL)GW 0742 GW 0742 functions as a dual PPAR agonist and antagonist, with its specific action depending on the dosage administered. Additionally, it demonstrates low level activity on various nuclear receptors. It has been identified as an antagonist for both androgen receptors and Vitamin D Receptors (VDR). Computational (in silico) modeling indicates that GW 0742 may also exert influence on thyroid hormone receptors. Multiple studies suggest that GW

GW-0742

GW-0742 functions as a dual PPAR-β agonist and antagonist, with its specific action depending on the dosage administered. Additionally, it demonstrates low-level activity on various nuclear receptors.

It has been identified as an antagonist for both androgen receptors and Vitamin D Receptors (VDR). Computational (in silico) modeling indicates that GW-0742 may also exert influence on thyroid hormone receptors.

Multiple studies suggest that GW-0742 can ameliorate experimentally-induced pancreatitis in mice. It has further been shown to mitigate hypertension in diet-induced obese mice. Currently, it is under investigation as a prospective antidiabetic agent and has demonstrated anti-inflammatory effects.

Concentration

20 mg/ml

Half-Life

24 hours

Disclaimer

This substance is exclusively available for laboratory research purposes. Sale terms and conditions apply. It is not intended for human consumption, or for use in medical, veterinary, or household applications. Please consult our disclaimer prior to making a purchase.

Included is a precision pipette marked per 0.2 ml!
Shake well before use.

Data sheet

GW-0742 – Solution, 600mg (20mg/mL)

Application Potent PPARβ and PPARδ agonist
CAS 317318-84-6
Molar Mass 471.5 g/mol
Chemical Formula C21H17F4NO3S2
IUPAC Name 2-[4-[[2-[3-fluoro-4-(trifluoromethyl)phenyl]-4-methyl-1,3-thiazol-5-yl]methylsulfanyl]-2-methylphenoxy]acetic acid
Synonyms GW0742, 317318-84-6, GW 0742, GW-0742, GW0742X, GW610742, GW-0742X, CHEMBL38508, CHEBI:79991, {4-[({2-[3-Fluoro-4-(Trifluoromethyl)phenyl]-4-Methyl-1,3-Thiazol-5-Yl}methyl)sulfanyl]-2-Methylphenoxy}acetic Acid, SR-05000000447, 3tkm, GW 0742X, GWdelta 0742, GW 610742, GW-610742, DSSTox_CID_20760, DSSTox_RID_79591, DSSTox_GSID_40760, MLS006011159
Storage Store at room temperature, tightly sealed, away from heat, light and moisture.
Solubility Soluble in DMSO, PEG 400
Organoleptic Profile Clear liquid
Physical Form Solution in PEG 400
Specification 20mg/mL ±5%
Terms This material is sold for laboratory research use only. Terms of sale apply. Not for human consumption, nor medical, veterinary, or household uses. Please familiarize yourself with our Terms & Conditions prior to ordering.

 

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SKU: 6087596396

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