SKU: 14563381055

Pure Methylation

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Description

Pure MethylationPure Methylation Advanced Support for Cardiovascular, Neurological, and Detoxification Health Pure Methylation is a specialized formula crafted to promote efficient methylation and maintain healthy homocysteine levels within the normal range. It includes five essential nutrients that play a crucial role in homocysteine metabolism: folate in the forms of calcium folinate and Quatrefolic for improved bioavailability, trimethylglycine, and vitamins B12,

Pure Methylation

Advanced Support for Cardiovascular, Neurological, and Detoxification Health

Pure Methylation is a specialized formula crafted to promote efficient methylation and maintain healthy homocysteine levels within the normal range. It includes five essential nutrients that play a crucial role in homocysteine metabolism: folate in the forms of calcium folinate and Quatrefolic® for improved bioavailability, trimethylglycine, and vitamins B12, B6, and B2. These activated nutrients work synergistically to support enhanced methylation processes and overall cardiovascular health.

  • A comprehensive formula supporting optimal methylation.
  • Key nutrients involved in homocysteine metabolism:
    • Folate (as calcium folinate and Quatrefolic®) for increased bioactivity.
    • Trimethylglycine.
    • Vitamins B12, B6, and B2 (provided in activated forms).
  • Enhances methylation and promotes overall cardiovascular health. 🌿❤️

Benefits of Pure Methylation Support Formula:

  • Supports Cardiovascular Health: Helps maintain healthy homocysteine levels, a key factor in cardiovascular wellness.
  • Promotes Neurological Well-Being: Enhances neurotransmitter production, supporting mental clarity, mood stability, and overall brain health.
  • Aids in Detoxification: Supports the body’s natural ability to methylate and eliminate heavy metals and environmental toxins.
  • Enhances Hormone Balance: Assists in the methylation of estrogen, dopamine, and epinephrine, promoting balanced hormone levels.
  • Boosts Cellular Health: Provides essential methyl donors that support DNA and cellular function, which are crucial for healthy aging and vitality.

A super B-complex designed for individuals with methylation deficiencies. Contains L-methylfolate for best bio-absorption. Contains 60 Vegetarian Capsules

 

Recommended For:

  • Individuals Focused on Cardiovascular Health: Ideal for those wanting to maintain healthy homocysteine levels and support heart health.
  • People with Cognitive or Neurological Concerns: Provides support for mental clarity and mood stabilization, especially for those experiencing brain fog or low mood.
  • Individuals Needing Enhanced Detoxification: Supports the methylation pathways that help detoxify environmental toxins, heavy metals, and hormone byproducts.
  • Those Seeking Hormone Balance: Beneficial for individuals aiming to maintain balanced estrogen and neurotransmitter levels.
Does Not Contain:
  • Gluten
  • Dairy
  • Soy
  • Genetically Modified Organisms (GMOs)
  • Sweeteners
  • Artificial Coloring
  • Artificial Preservatives

Elevate your health with Pure Methylation Support Formula, a targeted blend for optimal methylation, cardiovascular wellness, and detoxification. Experience the benefits of improved energy, clarity, and balanced hormone function to support a vibrant, healthier lifestyle.

Directions:

Take one capsule one to two times daily, or as directed by your healthcare professional.

Consult your healthcare professional prior to use. Individuals taking medication should discuss potential interactions with their healthcare professional. Do not use if tamper seal is damaged.

If you have any questions, please sign up for a FREE 15 consultation here

MTHFR and PURE METHYLATION

 

TECH TALK! Amy explains how PURE METHYLATION works...

What does BiomeIQ’s Pure Methylation do and How Does it Work?
MTHFR mutations cause a deficiency in methylation, which creates the inability to make enough methylation to support the entire body. They also create difficulty producing the enzyme Folate Reductase at an efficient rate. Meaning: Your body gets dirty faster from a buildup of toxins. Most of the symptoms associated with MTHFR are not as a result of the mutation but because the body is overloaded with lots of toxins that cause hormone dysregulations and make you feel sick in general.

How do you get rid of the toxins and make up for the methylation difficulty?

You can take methylation in the form of a handful of B vitamins, because the mutation is not just affecting methyl groups but also the enzyme Folate Reductase which methylate’s Folate. Pure Methylation is the combination of 3 B Vitamins: B12, B6, and Folate.
Why do a balanced B? If what you need is folate and you need it to be methylated, then why add a B12 and a B6?

Bodies work in ratios. They aren’t designed to work on a single B vitamin or any single nutrient for that matter. Think about foods with lots of B vitamins such as leafy green vegetables. You never find just one B vitamin, and this is because the mitochondrial cycle requires a number of B’s in a very specific ratio. Therefore, we use Pure Methylation in our clinic and recommend it to individuals with MTHFR mutations. Pure Methylation is the combination of 3 B Vitamins: B12, B6, and Folate and adheres to the same ratio that the mitochondrial cycle prefers with the already reduced form of the vitamin folate. This means it’s easy to absorb if you have MTHFR mutations.


Additional benefits of Pure Methylation:
• Supports neurological and cognitive health
• Supports the upkeep of healthy homocysteine levels
• Twice the amount of bioavailability
• Supports healthy methylation
• Supports a healthy heart

Keep in mind; methylation is a tool that the body uses to turn on and turn off reactions. It is a promoter, it turns on sequences. Do not with any methylation, including this product or any other supporting methylation, don’t take too much of it. If you over methylate, a whole bunch of different reactions in the body are created that can’t be controlled.

The key when picking out a product concerning methylation is to make sure that its pure and certified specifically for MTHFR. MTHFR bodies DO NOT like toxicity. Make sure it is a very clean physician grade vitamin such as our Pure Methylation. You also want to make sure you have the right ratio of B vitamins. Just taking a methylated folate can be a problem because the mitochondrial cycle is turned on by B12. Only driving one part of this cycle without the rest can create problems for the body.
If you’re looking for a safe product for effective methylation with the right balance of B vitamins and a clean product that’s easily absorbable, then we recommend Pure Methylation.

Pure Methylation, what is it? (Transcript from video)

This is probably one of my favorite products for MTHFR, and you can see, under 'biome IQ', it has the MTHFR Family logo over there, meaning it's certified and safe, and designed for MTHFR. It's the combination of three B vitamins, so it's B12, B6, and folate. And I'm sure you're going to ask the question, "Is it the right folate for MTHFR? So, is it a five prime methyltetrafolate?" It absolutely is. If you want to learn more about this product, more about the specifics, the technical side of things, just click on the next video.


Tech Talk (Transcript from video)

Pure methylation. Let's get down and dirty with the technical reason why this product works. So, I know most folks at MTHFR are keenly aware that what they really have is a deficiency in methylation, not making enough methylation as well as a difficulty producing properly the enzyme folate reductase. All right, so, it means that it gets dirty very fast. That's really the bottom line. And so, most of the symptoms associated with MTHFR are not a result of the mutation but acquiring lots of toxins that then cause hormone dysregulations and just generally make you sick.

So, the question is how do you get rid of those toxins, or basically, how do you make up for the methylation deficiency? Well, you can take methylation in the form of a handful of B vitamins because the mutation is not just methyl group, but also the enzyme folate reductase methylating the vitamin folate. Of course, becomes the holy grail for MTHFR, right? So, why do a balanced B? If what you need is folate and you need to be methylated, why add a B12 and a B6? So here's the thing, bodies work in ratios. They're not designed to work just on a single B vitamin. And if you think about foods that have lots of B vitamins like green vegetables, you never really find a vitamin that has just one B, and it's because the cycle, the mitochondrial cycle requires a number of these in a very specific ratio.

The reason I like this product over here is because, it adheres to the same ratio that the mitochondrial cycle prefers, with the already reduced form of the vitamin folate, meaning it's easy to absorb if you have MTHFR. One word of caution for everybody, I know, again, because you have MTHFR, and you probably read a lot about it, you're thinking, "Maybe let me methylate, and then let me methylate some more to keep feeling better." Keep in mind, methylation is a tool that a body uses to turn on and turn off reactions.

It is by definition, a promoter, turns on sequences. Do not, with any methylation that's true for pure methylation, it's true for any methylation, don't take too much of it. If you over-methylate, you create a whole bunch of reactions in a body that it can't control. So the key when you're picking up your own product for methylation, this one's mine, number one, you wanna make sure it's pure and certified specifically for MTHFR. MTHFR bodies don't like toxicity, so you wanna make sure it's a very, very clean nutraceutical, so physician grade Vitamin, which this one is. Number two, you wanna make sure that you get the right ratio of B vitamins. So just taking a methylated folate can be a problem because the cycle is actually turned on by B12. So if you just drive one part of the cycle without the rest, body's gonna have a problem

And then finally, depending on your MTHFR methylation, that's how you know how many of these pills to take. Here in clinic, what we normally do is a single A mutation. So A in a wild tape. We normally make the recommendation of one cap per day for a double C mutation, so least affected to most affected. A by itself or a double C the two sides of the spectrum for MTHFR. For a double C, depending on the person, depending on the symptoms, depending on their labs, what we normally recommend is two caps up to two times per day. All right, so again, if you're looking for a safe product for effective methylation, the balance of the B vitamins over here, the fact that it's such a clean product, the fact that it's so good at really driving that mitochondrial cycle, it's my favorite when it comes to methylation.

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SKU: 14563381055

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Johsz Family
New York, US
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Great value and super comfy!
Size: 7, Color: Sand
These shoes are so comfortable and my new go to for summer. They are lightweight and fit like a glove. Great value
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Reviewed in the United States on May 25, 2026
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Kindle Customer
Omaha, US
★★★★★ 5
Lovely sandals!
I highly recommend! These are so comfortable! Right out of the box, they can be worn all day. The velcro-adjustable straps are great for making for a perfect fit. The aren't clunky to wear, even though they appear to be. They're super cute, in my opinion. The sock liner is textile, so feet feel good all day, not slimy, like leather and suede can sometimes make feet feel if socks aren't worn.
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Pamela
Carnegie, US
★★★★★ 5
Cute and Comfortable
Size: 10, Color: Black
This is my second pair. I bought the sand color at my local Macy's. I got their last pair. I have issues with back pain and ankle swelling and pain. These are so comfortable I had to get them in Black. The adjustable straps are great. My feet are a little bit wider because of the swelling issues. So if you have very narrow feet these might be a little big. You might want to go down a half a size. But otherwise I wear a size 10 and they fit perfectly. I don't think the picture does the color justice. The black almost looks like velvet, it's very deep and rich. I wore them out today for the first time and got lots of compliments. The footbed is very comfortable with the memory foam. Lots of support. I noticed my back and ankle pain is much better wearing these. I've never owned UGG before. If these hold up really well and continue to stay comfortable, I will be purchasing other styles for fall and winter.
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Reviewed in the United States on May 1, 2026
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Tilly
Bozeman, US
★★★★★ 5
Great fitting sandals
Size: 7.5, Color: Sand
Great fitting. Beautiful. Fit like a glove. Great to walk in. Great quality. Lightweight. All in one gorgeous sandals.
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Chelsea, US
★★★★★ 5
My new favorite summer sandal!
Size: 8.5, Color: Bay Fog
I am loving these shoes so far this summer! The color is so cute, perfect for a light summer palette. It's the perfect light purple that doesn't make me look pale or washed out. For reference, I have fair to light neutral skin tone. They are SO comfortable - a little too comfortable for a shoe, it's more comfortable than my ugg slippers! They do take a second to put on as you have to either force your ankle in without unstrapping the back - don't judge me - or undo them. Thankfully they have a strap to help get them on easily. I love these shoes. I am a medium width, but I think these have some wiggle room since both the straps are velcro and adjustable somewhat. They are easy to walk in, hold onto the foot, have been more balanced than some others I have had in this platform style, and are very cushioned to walk in. Slight arch support to me but I have somewhat high arches so if you are more flat footed or standard arch these will give you even better support. Really impressed with these. They are more casual but work with many different outfits from sundresses to jeans. For me, these were a great buy and I will be wearing them all summer.
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Reviewed in the United States on June 7, 2026

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