SKU: 28207398552

Pure CoQ Supreme

$61.19 $67.99
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Ships within 48 hours · Estimated delivery Jul 17 - Jul 22

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Description

Pure CoQ SupremePure CoQ Supreme: Dual Action Cardiovascular Support for Optimal Heart Health Pure CoQ Supreme combines high potency, patented ingredients in a dual action formula to support heart health, energy production, and cardiovascular function. With MaxSimil monoglyceride fish oilan IFOS five star certified source with 3x greater absorption of EPA and DHAand Kaneka Q10, a bioidentical form of CoQ10, this advanced supplement helps maintain natural CoQ10

Pure CoQ Supreme: Dual-Action Cardiovascular Support for Optimal Heart Health

Pure CoQ Supreme combines high-potency, patented ingredients in a dual-action formula to support heart health, energy production, and cardiovascular function. With MaxSimil® monoglyceride fish oil—an IFOS five-star certified source with 3x greater absorption of EPA and DHA—and Kaneka Q10®, a bioidentical form of CoQ10, this advanced supplement helps maintain natural CoQ10 levels, enhancing heart health and protecting against oxidative stress.

Benefits of Pure CoQ Supreme:

  • Supports Cardiovascular Health: Promotes heart function and vascular integrity, helping to reduce strain on the cardiovascular system.
  • Enhances Energy Production: CoQ10 boosts mitochondrial energy production, particularly in heart cells, supporting optimal energy levels.
  • Protects Against Oxidative Stress: Provides strong antioxidant support, reducing oxidative damage to cells and tissues within the cardiovascular system.
  • Improves Omega-3 Absorption: Delivers EPA and DHA with 3x greater absorption, enhancing the anti-inflammatory and heart-protective benefits of fish oil.
  • Maintains Healthy CoQ10 Levels: Helps sustain natural CoQ10 levels in plasma and tissues, especially beneficial as CoQ10 levels tend to decrease with age.

More than twice as bioavailable as oil-based/nano dispersed Cofactor-Q formulas to meet the metabolic needs of MTHFR enzyme reduction* Contains 60 Softgels. 

Pure COQ Supreme is a medical grade version of COQ10 and it’s pure enough to meet the requirements of someone who has MTHFR. COQ10 is a critical co factor to running the metabolic cycle. The metabolic cycle takes place within the mitochondria and this cycle is the main producer of our energy and our detoxifiers. The mitochondrial cycle has three main cofactors that are needed to support the process of energy production. The beginning stage of the cycle relies on vitamin B12, the middle stage relies on a specific form of COQ10, and the last stage relies on using Folate Reductase to reduce the vitamin Folate.
COQ10 is an essential step in the cycle, which is why it’s important to make sure your body is getting enough of it.

Recommended For:

  • Individuals Focused on Heart Health: Ideal for those looking to support cardiovascular function and reduce oxidative stress on the heart.
  • Aging Adults: Especially beneficial for older individuals needing support for natural CoQ10 levels and overall heart health.
  • People with Low Energy or Fatigue: Helps those experiencing low energy or fatigue, providing cellular-level energy support.
  • Athletes and Active Individuals: Provides optimal heart and muscle support, aiding in endurance and recovery.
  • Those Seeking Antioxidant Protection: Suitable for anyone looking to boost antioxidant intake and protect against free radical damage.

The fish oil improves the absorbability of the COQ10. Our Fish oil was developed using a delivery system that enhances absorption of lipid-based
and lipid-soluble nutraceutical and food ingredients. This allows bypass of the body’s normal fat digestion process. Our new COQ10 provides all the benefits of EPA and DHA as well as the expected and desirable benefits of their metabolites. EPA plays a role in supporting healthy cardiac and circulatory systems. DHA is an
essential structural component of the central nervous system.

From a quality perspective, every batch of fish oil is IFOS five-star certified to ensure the highest standards for
purity, potency, and freshness. The fish oil is also non-GMO, certified sustainable
from Scandinavia, and antibiotic-free.

  1. Fortin S, inventor; Centre de Recherche sur les Biotechnologies Marines, assignee. Compositions comprising polyunsaturated fatty acid monoglycerides or derivatives thereof and uses thereof. US patent 8,198,324. June 12, 2012.
  2. MaxSimil Patented Lipid Absorption Technology Clinical Study Report: MaxSimil® 3020 Omega-3. Sherbrooke (Québec), Canada: Ingenutra; 2015. [Unpublished, internal data]

Does Not Include:

  • Gluten
  • Dairy
  • Soy
  • Genetically Modified Organisms (GMOs)
  • Artificial Sweeteners
  • Artificial Coloring
  • Artificial Preservatives

Warnings:

  • Keep out of reach of children.
  • Store in a cool, dry area.
  • Variations in temperature may cloud the softgels, this does not affect the formula's efficacy or safety 
  • Do not refrigerate
  • Sealed with an imprinted safety seal for your protection.

Experience comprehensive heart support, enhanced energy, and powerful antioxidant protection with Pure CoQ Supreme, a potent formula designed to support cardiovascular health and overall vitality.

Directions:

Take one softgel twice per day, or as directed by your healthcare professional.

Consult your healthcare professional prior to use. Individuals taking medication should discuss potential interactions with their healthcare professional. Do not use if tamper seal is damaged.

Shipping Notes
  • Free Standard Shipping on $100+ Orders to the USA.
  • Except Preorder products are shipped in 48 hours.
  • Delivery to the USA:
  1. Standard Shipping : 3-10 business days
  • If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
  • We offer a 30-day return/exchange service after receiving.
  • Final sale items are not eligible for returns or exchanges.
  • To process your return/exchange, please contact us at [email protected]
  • Please click here for more details>>> Return & Exchange Policy
SKU: 28207398552

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4.3 ★★★★★
Based on 22 reviews
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Product Reviews
T
Verified Purchase
Taylor Ashley
Omaha, US
★★★★★ 5
Holy Grail of Moisturizers
Style: Restorative Protective Cream-3.3 Fl Oz
I bought this after hearing a dermatologist on Instagram rave about this cream and now I see why. As someone who suffers from pretty severe eczema this is my go to holy grail for flair ups. Perfect for sensitive skin and can be used daily. It is very thick so provides a thick layer of moisture on your skin. I will say I have bought 2 sizes in this and the smaller size (1.3fl oz) did separate and had a liquid part that would come out. I have bought numerous tubes of the larger size (3.3fl oz) and never had an issue with separation with the larger size. I’m learning as I get older that more expensive does not mean better quality skincare. This is one that is not only affordable, but will also give you noticeable results. I have everyone in my whole family using this product!
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 17, 2026
E
Verified Purchase
Elizabeth Browning
Los Angeles, US
★★★★★ 5
I Just Want to Help People With Skin Problems!
Style: Tolerance Control Soothing Skin Recovery Cream
I so wish I had known about this skincare line a long time ago, but just glad I did find it at all. I have rosacea (including ocular rosacea) diagnosed by a dermatologist. I had been through all the typical stores and websites, trying so many things over the last 15 years. Yes, most were supposed to be for people with skin problems. EVERY SINGLE TIME I tried something, within five minutes, my skin was bright red. My skin reacted to EVERYTHING. I started to believe there was not one single product on the entire planet that my skin would not react to! It was so frustrating. Purchase, fail, repeat. Thing is, I had tried their spring water spray. I sort of ignored all the other products until I was talking to someone randomly and they asked if I had tried Avene. Honestly I decided maybe this was providence and that I had better try it just to be on the safe side. What would life be like if I had ignored their advice and not tried it? If this company ever goes out of business, I will have to live with terrible skin because I already know there is nothing else out there. I had read a review whereby someone said their doctor told them the longer they used the products, the better their skin would get. This is completely true. But even initially, all I cared was that I could relieve the dryness with SOMETHING that did not turn my skin RED IMMEDIATELY! Even THAT, I would have been happy with! Now for the rest of the benefits. I had the good intuition to purchase two of these when they were on sale. I am so glad I did. I use it like crazy every chance I get. It just feels so good going on and I like touching my skin even after the product dissipates. No redness, no irritation, it actually CALMS my skin. And makes it like, well, "real skin." I'm glad I also got the thicker version in the tube, Cicalfate. This is my go-to for dryer areas and in the winter. The two together along with the water spray, if you like to use something like that, are a great overall program. Definitely other things I would like to try. Again, my goal was to help others who have skin problems because everything else out there has no concept whatsoever of calming the skin, but the exact opposite -- irritating it worse (even if those products are supposed to help with redness or irritation). And I felt the company truly deserves a shout-out because they GET IT when it comes to skincare products. Whatever they've done, they are experts, far more than all the other skincare lines and I don't care how long those have been around. If it doesn't immediately tell you your skin "likes it" and shows it by not reacting or immediately getting better, why on earth would you pay your hard-earned money to buy it and keep using it? It's worth every penny, don't bat an eyelash, your skin is worth that and more. If it's on sale, get a lot of it because trust me, you are going to want and need it. You will be so glad you got more than one. I definitely am! THANK YOU, AVENE, WE LOVE YOU HERE IN AMERICA! YOU UNDERSTAND SKINCARE LIKE NO OTHER COMPANY! Update: Wanted to comment that I'm still so grateful for a product that does FAR MORE than what you expect! I recently bought more. I watch my skin calm down the minute I put it on. I don't know entirely how the ingredients do what they do, but to the company ... please don't fix what isn't broken! Too many companies have a good thing and then change it. Please don't, the products are perfect and far beyond expectation! I also wanted to mention it seems the Tolerance tube will get EVERY LAST BIT out, you won't be wondering if there is anything left you are discarding. The Cicalfate tube is a bit different, it's more like a squeeze tube. But I feel I can still get the product out to use it all. That said, you get your money's worth. I'm also starting to use the Cicalfate on my hands in the winter, too (which are sadly starting to show my age). But this product line has literally CHANGED MY LIFE! BUY IT, it's the REAL DEAL!
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on August 10, 2025
J
Verified Purchase
Jeanie
Bozeman, US
★★★★★ 5
Love this cream
Style: Tolerance Control Soothing Skin Recovery Cream
I absolutely love the Avène Tolerance Control Soothing Skin Recovery Cream — it’s become a sanctuary for my sensitive skin. From the very first application, I noticed how calming and gentle it feels. The texture is rich yet lightweight, absorbing beautifully without any greasiness. This cream has been a game‑changer for days when my skin feels irritated, reactive, or overwhelmed. It instantly soothes redness and discomfort, and over time my skin feels stronger, more balanced, and resilient. What really stands out is how comfortable and nourished my skin feels all day long — no tightness, no irritation, just pure relief.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on February 26, 2026
T
Verified Purchase
Tiffany
Fort Morgan, US
★★★★★ 5
Must have for rosacea sensitive skin!
Style: Tolerance Control Soothing Skin Recovery Cream
I have fair, sensitive skin & since being in peri-menopause I suddenly have rosacea. This cream is SO gentle on the skin but so instantly calming. It hydrates so well & a little goes a long way. I will be buying this over & over from now on!
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on April 15, 2026
A
Verified Purchase
Amazon Customer
Bozeman, US
★★★★★ 5
Great for Sensitive Skin
Style: Tolerance Control Soothing Skin Recovery Cream
I have very sensitive skin and have tried everything to try and prevent rosacea flairs. I recently came across this brand and I absolutely love this recover cream. I consider this now the holy Grail for Rosacea and sensitive skin. It makes my skin feel hydrated and non-reactive. It is soothing and I just cannot get enough of it. It is pricy but it is worth it to not have my face constantly feeling like its burning or irritated.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on April 2, 2026

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