SKU: 45373217776

Histofix®-Safe 20 ml (11 PCS)

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Description

Histofix®-Safe 20 ml (11 PCS)Patented by ITW Reagents, this innovative closed loop safety device for the secure fixation and transportation of small histological specimens prevents user exposure to carcinogenic formaldehyde solution and ensures safe and convenient handling of biopsies by healthcare professionals. Histofix Safe: Innovative Solution for Safe and Comfortable Biopsy Handling The Histofix Safe system from PanReac AppliChem ITW Reagents is a state of the art container

Patented by ITW Reagents, this innovative closed-loop safety device for the secure fixation and transportation of small histological specimens prevents user exposure to carcinogenic formaldehyde solution and ensures safe and convenient handling of biopsies by healthcare professionals.

Histofix®-Safe: Innovative Solution for Safe and Comfortable Biopsy Handling
The Histofix®-Safe system from PanReac AppliChem ITW Reagents is a state-of-the-art container for the safe handling and fixation of biopsies in clinical diagnostics. It is specifically designed to protect medical professionals from exposure to the carcinogenic formaldehyde solution commonly used in pathology and histology. Formaldehyde can pose significant health risks with regular contact, including respiratory irritation, allergic skin reactions and an increased risk of tumours in the nasal and throat areas. With its closed-loop system, Histofix®-Safe minimises the risk of fumes and droplets escaping, which can occur with similar systems, protecting against inhalation and skin contact.

A bidirectional valve enables the safe transfer of formaldehyde solution from the filled to the empty container without releasing fumes. The integrated grid with safety cap ensures that even sticky samples can be placed and removed safely without contact with formalin. In compliance with Regulation (EU) 2017/746 on in-vitro diagnostic medical devices (IVDR), Histofix®-Safe offers maximum reliability and safety. Available in various sizes, this innovative system combines optimal protection with ease of use, making it an indispensable tool for safe and efficient biopsy processing.

Key Features
Histofix®-Safe state-of-the-art container for biopsies
Ready-to-use preservative for clinical diagnostics
Contains 4% buffered, methanol-stabilized formalin
Safe and convenient handling of tissue samples by medical professionals
Closed-loop system for fixation and transport of small histological specimens
Protects the user from exposure to carcinogenic formaldehyde solution
Complies with Regulation (EU) 2017/746 on in-vitro diagnostic medical devices (IVDR)
Offers superior advantages over comparable systems thanks to the bi-directional valve
Formaldehyde is transferred from the filled container to the empty container with the sample under pressure
Grid with safety cap ensures the absence of fumes
Grid allows safe placement and removal of sticky samples without formalin contact
Optimal combination of workplace protection and ease of use
Excluded from the right to return
Available in different sizes

Formaldehyde - A Toxic Substance in Everyday Medical Use
Formaldehyde is a colourless, pungent-smelling gas that is present in aqueous solution as formaldehyde solution. Due to its disinfectant and preservative properties, it is commonly used in the medical field, particularly for fixing tissue samples. Despite its usefulness, formaldehyde poses significant health risks to medical professionals.

Even at low concentrations, formaldehyde can irritate the mucous membranes of the eyes and airways, leading to symptoms such as burning eyes, sore throat, and coughing. Repeated skin contact with formaldehyde can also cause allergic reactions, including rashes and dermatitis. Some individuals may develop a sensitisation that causes intensified reactions upon further exposure. Formaldehyde is classified as carcinogenic to humans. Chronic exposure often leads to inflammation, which serves as a breeding ground for cancer cell development. Tumours can develop, especially in the nasal and throat area, where formaldehyde is most concentrated in the air.

Medical professionals who regularly work with formaldehyde solution – such as in pathology or during sample collection in practices – are at increased risk. Inhalation of formaldehyde is particularly dangerous, as even low concentrations can irritate the airways and have long-term carcinogenic effects.

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Exchange/Return Notes
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SKU: 45373217776

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4.3 ★★★★★
Based on 28 reviews
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Verified Purchase
Kimmi Bear
Pawtucket, US
★★★★★ 4
DONT BUY THE ELEPHANT, ITS NO GOOD. but GR8 BRAND!
Color: Checkers - Elephant (Gray), Size: Large
The elephant toy had no trunk by the FIRST day! The elephant now looks like an angry Koala bear OR an angry trunk less elephant(whichever u want to say) I LOVE the donkey and dinosaur toys so I bought the elephant confidently, thinking I had nothing to worry about. I wouldn't have spent money on this knowing the trunk would be chewed off in a matter of minutes. My Bella usually chews but she has had her donkey and dinosaurs with the chew guard for MONTHS and there are NO TEARS OR RIPS even with her playing and chewing on them ROUGHLY all day. If you buy any of these type toys I DO highly recommend the donkey or dinosaurs ONLY. The elephant being chewed up in a matter of minutes really makes me angry that I ever spent the money on it. HAD I known it wouldn't be the high quality dog toy I'm used to from GoDog, I would've just bought a second donkey or dino! Now Bella doesn't get her new toy for the month (I try 2 buy her a new stuffed toy or 2 about 1 time a month whenever I have the extra money for it) I guess she will have to go without this month because I spent it on this now trunkless elephant/angry koala:( Whichever name you call it, it is now going to be trash. UPDATE! If you contact the GODOG company they will send one replacement toy for your pet! They also asked me my pet's size, breed and age in order to send the best possible toy! They sent Bella a snake that has held up Extremely WELL! It's great and so far is my favorite(and one of Bella's favorites) The snake has less sqeaky things in it so she doesn't have the drsire to tear it apart immediately to retrieve them by rippong it to shreds:) My updated rating is for the MANUFACTURER'S GREAT CUSTOMER SERVICE. The fact that they actually replaced it was good but the fact that they went that extra mile by researching the best toy match for my Bella was above and beyond! If you have a Godog toy that went bust right away, contact the manufacturer for a replacement. If you give them your dog's age, weight and breed they will even try to match your pets replacement toy with something that is better suited to your dog's chewing style. (Bella's style is destructive haha) Good luck, ya'll!
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Reviewed in the United States on October 26, 2016
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Verified Purchase
AmberC
Cuba, US
★★★★★ 5
My Dobermans favorite toy to destroy, and one of our recommended picks.
Color: Checkers - Elephant (Gray), Size: Large
Ok, here's an honest breakdown review. I have a 6 month old Doberman who shreds every stuffed animal and dog bed he's come across. He's one of the worst chewers I've owned. We have tried a WIDE variety of stuffed toys. That said, this elephant is his favorite toy. I have ordered 4 of them so far, and just ordered another 4-pack on a buy three get one free deal. The elephant stands out above all the other stuffed creatures from goDog for me as to durability. Hence why I keep buying more. But they usually last about 2-3 weeks on average. In our house, the poor creatures are subjected to vicious, crazy, shaking of the head, helicopter type rotation. It' so hard if it hits your bare arm or leg it actually stings especially when its wet. Then the old, put it between his legs laying down, tearing at the legs action. The limbs are usually the first things to go over time. But they are each almost self sealing, so you clean up as little fluff and keep using it. Eventually the pup reaches the main body and finishes it off. For a normal light to normal chewer, one of two will get you a long way. For those of us resigned to having zoomie type manic chewers that need a constant supply of toys, 2-3 week durability is pretty sound too. I do not recommend the green cheaper monster. It lasted about 45 minutes. The free replacement took about 3 days. Hopefully this aids you in your decision!
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Reviewed in the United States on June 10, 2026
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Verified Purchase
Ashley
Los Angeles, US
★★★★★ 5
Very durable for rowdy pups
Color: Checkers - Elephant (Gray), Size: Large
This toy has outlasted any other dog toy I have ever bought. I have one large and one medium dog who share toys, fight over toys, chew them to death and still play with them. It might be because it isn't one of their favorites. I don't know. All I know is that our house is littered with dog toys in different states of destruction and this elephant toy has very little damage. It has definitely been in the dog toy rotation. I had this toy for 2 months without any major damage. The day I wrote the review the dogs tore the leg off! I still think it is a good toy. Some toys lose the stuffing or squeaker the first day.
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Reviewed in the United States on May 18, 2025
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Verified Purchase
Lady
Charlottesville, US
★★★★★ 5
Great toy for a smaller dog
Color: Checkers - Dinos Bruto (Purple), Size: Mini
This is a small, firm, sturdy toy designed for chewing. It isn't a soft toy and it does not have a squeaker. My dog is only 8 lbs, and this is a perfect size for her. I discovered these smaller toys through my groomer. Other manufacturers make this size, as well. The "hard chew" part indicates that this toy will not be chewed to death easily. The oldest one that we have is still in good condition. It's a baby duck (also available on Amazon) and it's over a year old. The dinosaur is colorful, easy to throw, and a really cute. Every night, my dog gives these small toys a bath, cleaning them up by licking each one before going to sleep. It's as if they are her babies. Since she never had a liter, my vet said that they are about the size that her babies would have been, so she may see them as her babies. She treats them well. Every now and then they go" swimming" in the washing machine and come out looking bright and new again.
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Reviewed in the United States on January 2, 2026
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Verified Purchase
Lori
Whiting, US
★★★★★ 4
Updated, still going !! didn't last two minutes.
Color: Checkers - Elephant (Gray), Size: Large, Color: Checkers - Elephant (Gray), Size: Large
I hated giving this a 1 star, because it was so cute when I unpacked it today. I just gave it to my dog and in less than two minutes he has a hole ripped in it.! he loves it so I don't wanna take it away from him, but I'm sure it's going to be gone in another few minutes. Why can't someone make a stuffed animal for a dog that lasts like they say so on their listing? I really should take it away from him and send it back, but I don't have the heart. I had to come back and give this a better review. it deserves at least four stars because even though he ripped holes in it, this one has lasted way longer than any other toy. He's actually still playing with it, and it still has some crinkle left to it so he didn't destroy the whole thing as quickly as he did other stuffed animals. I will certainly buy another one because at least it lasted a week so far!
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Reviewed in the United States on January 6, 2026

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