SKU: 71228785598

Vitamin B-12 - 5000 mcg, 120 lozenges

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Description

Vitamin B-12 - 5000 mcg, 120 lozengesBenefits: Introducing ProHealth Longevity's Vitamin B12, a unique combination crafted to harness the synergistic benefits of multiple forms of Vitamin B12. This innovative formula incorporates methylcobalamin, dibencozide, cyanocobalamin, and hydroxycobalamin, each selected for their unique contributions to cellular health, energy metabolism, and overall longevity. While many B12 supplements focus solely on one form of B12, ProHealth Longevity's

Benefits:

Introducing ProHealth Longevity's Vitamin B12, a unique combination crafted to harness the synergistic benefits of multiple forms of Vitamin B12. This innovative formula incorporates methylcobalamin, dibencozide, cyanocobalamin, and hydroxycobalamin, each selected for their unique contributions to cellular health, energy metabolism, and overall longevity. While many B12 supplements focus solely on one form of B12, ProHealth Longevity's Vitamin B12 embraces a comprehensive approach, recognizing the diverse roles and benefits offered by each variant. From supporting brain function to enhancing energy levels and combating age-related declines, our formula is designed to optimize B12 status and promote vitality at every stage of life.

  • Plays a crucial role in maintaining cellular integrity by aiding in DNA synthesis and repair
  • Acts as a cofactor in the conversion of carbohydrates, fats, and proteins into usable energy
  • Supports healthy brain aging by aiding in the regeneration of myelin, the protective sheath around nerve fibers
  • Provides mood support by serving as a cofactor in the synthesis of neurotransmitters

View Certificate of Analysis

Research-Supported Benefits:

Enhances cellular health. Vitamin B12 is a pivotal player in the synthesis and repair of DNA, critical processes that safeguard cellular integrity. Research has linked Vitamin B12 deficiency to disruptions in DNA synthesis and repair mechanisms, underscoring its importance in maintaining genetic stability. (1) Vitamin B12 offers further cellular protection by supporting telomere maintenance, the protective caps at the ends of chromosomes. Telomeres play a vital role in preserving DNA integrity during cell division, and their maintenance is closely linked to longevity and overall health. By supporting telomere integrity and DNA repair mechanisms, Vitamin B12 contributes to enhanced cellular resilience and longevity, offering comprehensive support for optimal aging.

Heathy heart aging: Vitamin B12 aids in the reduction of homocysteine levels, an amino acid implicated in various forms of DNA damage, including DNA strand breaks. Elevated homocysteine is associated with accelerated cardiovascular aging and increased risk of cardiovascular events. (2) Research shows that increasing vitamin B12 intake may reduce homocysteine levels up to 7%. (3)

Promotes energy production. Vitamin B12 is indispensable for sustaining energy levels, with its deficiency linked to reduced energy production in the body. Through its involvement in synthesizing SAMe, a vital methyl donor nutrient, Vitamin B12 supports mitochondrial function and the generation of ATP, the primary energy currency of cells. As we age, ATP production tends to decline, exacerbated by decreasing levels of Vitamin B12. This decline can lead to age-related fatigue and diminished stamina. Supplementation with Vitamin B12 may offer a solution by replenishing stores and potentially mitigating the decline in ATP production associated with aging.

Promotes Cognitive Health. Vitamin B12 plays a crucial role in maintaining cognitive function, and its deficiency is strongly associated with cognitive decline and memory impairment. (4) Its diverse functions in methylation, neurotransmitter synthesis, and mitochondrial activity are essential for optimal brain health. Notably, Vitamin B12 shows promise in mitigating age-related neurodegeneration by regulating inflammatory processes and protecting against the formation of amyloid beta (Aβ) plaque. (5) Supplementation with Vitamin B12 has potential to alleviate symptoms linked to accelerated brain aging and support overall cognitive well-being.

Supports Mood. Vitamin B12 plays a vital role in the synthesis of essential mood-regulating neurotransmitters, including serotonin and dopamine. Serotonin, known as the "feel-good" neurotransmitter, is synthesized from the amino acid tryptophan in a process facilitated by SAMe, which in turn relies on sufficient levels of Vitamin B12 for optimal function. Similarly, dopamine, a neurotransmitter linked to reward, pleasure, and motivation, also depends on Vitamin B12 for its synthesis. Scientific studies have demonstrated that deficiency in Vitamin B12 correlates with mood dysregulation, contributing to symptoms such as irritability and personality changes. (6)

References:

1. Alzoubi KH, Bayraktar E, Khabour O, Al-Azzam SI. Vitamin B12 protects against DNA damage induced by hydrochlorothiazide. Saudi Pharm J. 2018;26(6):786-789. doi:10.1016/j.jsps.2018.04.005

2. Yan Y, Yin Y, Feng X, et al. Homocysteine aggravates DNA damage by impairing the FA/Brca1 Pathway in NE4C murine neural stem cells. Int J Med Sci. 2020;17(16):2477-2486. Published 2020 Sep 9. doi:10.7150/ijms.49246

3. Maruyama K, S Eshak E, Kinuta M, et al. Association between vitamin B group supplementation with changes in % flow-mediated dilatation and plasma homocysteine levels: a randomized controlled trial. J Clin Biochem Nutr. 2019;64(3):243-249. doi:10.3164/jcbn.17-56

4. Jatoi S, Hafeez A, Riaz SU, Ali A, Ghauri MI, Zehra M. Low Vitamin B12 Levels: An Underestimated Cause Of Minimal Cognitive Impairment And Dementia. Cureus. 2020;12(2):e6976. Published 2020 Feb 13. doi:10.7759/cureus.6976

5. Lam AB, Kervin K, Tanis JE. Vitamin B12 impacts amyloid beta-induced proteotoxicity by regulating the methionine/S-adenosylmethionine cycle. Cell Rep. 2021;36(13):109753. doi:10.1016/j.celrep.2021.109753

6. Sangle P, Sandhu O, Aftab Z, Anthony AT, Khan S. Vitamin B12 Supplementation: Preventing Onset and Improving Prognosis of Depre**ion. Cureus. 2020;12(10):e11169. Published 2020 Oct 26. doi:10.7759/cureus.11169

  • When taken as a supplement, Vitamin B12 is released in the stomach and binds to intrinsic factor, a protein produced by the stomach lining.
  • The Vitamin B12-intrinsic factor complex travels to the small intestine, where it is absorbed into the bloodstream through specialized receptors in the intestinal lining.
  • Once in the bloodstream, Vitamin B12 is transported to various tissues and cells throughout the body, where it exerts its functions.
  • Vitamin B12 plays a crucial role in energy metabolism as a cofactor for the enzyme methionine synthase, which helps convert homocysteine to methionine. Methionine serves as a precursor for S-adenosylmethionine (SAMe), a key methyl donor in cellular reactions.
  • SAMe participates in methylation reactions essential for ATP synthesis, the primary energy currency of cells, thus contributing to overall energy production and vitality.
  • Vitamin B12 helps maintain mitochondrial health and facilitates neurotransmitter synthesis, promoting youthful cognitive functioning and reducing the risk of age-related cognitive decline.
  • Vitamin B12 is crucial for brain health and cognitive function, as it supports mitochondrial function and neurotransmitter synthesis. Mitochondria in brain cells require Vitamin B12 for energy production, which is essential for maintaining neuronal activity and cognitive processes.
Supplement Facts
Serving Size: 1 Lozenge
Servings Per Container: 120
Amount Per Serving %DV
Vitamin B12 5000 mcg 208333%
  Methylcobalamin 1786 mcg 74417%
  Dibencozide 1786 mcg 74416%
  Cyanocobalamin 1071 mcg 44625%
  Hydroxycobalamin 357 mcg 14875%
% Daily Values are based on a 2,000 calorie diet

REV. 12.23

  • OTHER INGREDIENTS: Sorbitol, natural strawberry flavor, rice extract blend, natural color (grape skin extract), and silicon dioxide.
  • DOES NOT CONTAIN: Dairy, egg, soy, wheat, gluten, fish, shellfish, tree nuts, peanuts.
  • SUGGESTED DAILY USE: Take 1 lozenge daily, allow lozenge to fully dissolve under your tongue, then swallow, or as recommended by your healthcare professional.
  • NOTE: Natural color variation may occur. Store in a cool, dry place, away from direct sunlight. Do not use if tamper-evident packaging is broken. KEEP OUT OF REACH OF CHILDREN.
  • CAUTION: Not intended for use if you are pregnant or nursing. Not formulated for use in children. If you have a medical condition or are taking medications, consult with your healthcare professional before using this product.
  • Optimize B12 Status. ProHealth’s Vitamin B12 was specifically formulated to reduce symptoms of age-related health decline associated with low vitamin b12 levels.
  • Unique Combination: Compared to other supplement brands using isolated forms of vitamin b12 ProHealth’s Vitamin B12 contains four different forms of vitamin B12, each selected for their unique contributions to cellular health, energy metabolism, and overall longevity.
  • Quality Manufacturing Practices. All of our products are manufactured in an FDA-registered, GMP-certified facility.
  • Third-Party Tested in the USA. Every batch is third-party tested in US laboratories to ensure the highest quality, purity and potency. Certificates of Analysis are available.
Shipping Notes
  • Free Standard Shipping on $100+ Orders to the USA.
  • Except Preorder products are shipped in 48 hours.
  • Delivery to the USA:
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  • If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
  • We offer a 30-day return/exchange service after receiving.
  • Final sale items are not eligible for returns or exchanges.
  • To process your return/exchange, please contact us at [email protected]
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SKU: 71228785598

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4.8 ★★★★★
Based on 14 reviews
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Product Reviews
M
medpeds
Pawtucket, US
★★★★★ 5
Beautiful book with history, destination information, and photos
Format: Hardcover
I knew very little about the Camino de Santiago prior to obtaining this book. However, the book is stunning in its information about destinations, history, towns you'll pass through along the way, and beautiful photos that create desire to hike or bike the trail in the immediate future. I found myself engulfed in this book and wanting to do several of the trails as soon as possible! The book, unlike other DK books I own, is hard cover. It's solid and durable and could easily be a coffee table book rather than a hiking guide. In fact, I think it may be meant in this way to be used rather than a take-along for a long hiking trip. If you're thinking about exploring the Camino de Santiago, this is a must read!
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on January 14, 2026
R
Rabbit 519
Los Angeles, US
★★★★★ 4
A very good book if you will travel the Camino de Santiago as a pilgrim
Format: Hardcover
This book captures the flavor of each of eight Caminos to reach Santiago de Compostela (there are more than that, but not given more than a mention - these are the main ones). The Caminos take you from where they enter Spain from France and Portugal all the way to Santiago de Compostela; the exception is the one from Lisbon. You can almost "feel" the experience of each walk. The book will help you select a Camino, based on from where you are coming, what you'd like to see (scenery, towns, villagers, etc.), and how much stamina you have. The book starts off with a wonderful history of the the Caminos from when they were developed through modern times, and how they changed over time, not just in terms of physical changes, but in terms of the types of people who traversed them (pilgrims to hippies) and how they evolved with various religions and politics of the times. There is a very nice synopses of the eight Caminos, highlighting the differences between them. This provides an overview of why you may or may not consider taking that Camino. The book then goes into detail about each one, elaborating on what I wrote in the first paragraph above. This is where one gets an excellent "feel" for the Camino, enabling you to determine if it is for you or not. It also gives you basics on things to see and do along the way, including places that would be great and welcoming for pilgrims. Don't expect too much detail here, but certainly enough to give you the flavor of the Camino. All sections, but especially this one, have excellent photos to complement the text. The culminating chapter, of course, is the one on Santiago de Compostela. This one was a bit disappointing, as it provided only a bit over one page of text on the sites there. I would have thought there would be more, especially about the Cathedral itself, as that is the destination the travelers had spent days to reach. Instead, it basically just listed a bit more than bullets of what to see in the Cathedral. One third of the text in this Chapter was about the museums. There was practically nothing about the squares around each side of the Cathedral and all the places along them. For this city, I would suggest a different tour book if you want to see more. I have the hard cover book, which was very nice for me to read at home. However, if I were to go on one of the Caminos, I would take no more than a Kindle, which is nowhere near as unwieldy as a large, heavy book. If I didn't like Kindles, I would want to bring a paperback, but sadly, the book is not available in paperback. Overall, I believe that the way the author enables one to experience the Caminos is well worth the cost of the book.
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Reviewed in the United States on April 6, 2026
M
Matt
Natrona Heights, US
★★★★★ 5
great guide to hiking (or biking) the Camino de Santiago trails
Format: Hardcover
Spain is one of my favorite European destinations, and while I have not done the Camino de Santiago yet, it is an area that is definitely on my radar for an upcoming trip. This book focuses on the trails and the regions they pass through, and gives quite a bit of detail and background to successfully plan a trip there. Now, I am not religious, and I am purely interested in the historical and cultural aspects of the region, not looking to have a spiritual experience. Fortunately the book is written in such a way that it is respectful to those who *are* looking for the latter, but it doesn't focus on it as much as I feared that it might. So it'll be useful to me in planning my travels. The one issue that I have about this book, which I *almost* took a star off of my rating for, is that the book is a little *too* sturdy. My big complaint with the regular DK travel guides in recent years is that they've gone to cheaper paper, cheaper covers, and cheaper binding than they used to use, to the point that they feel almost fragile to me. This book, ironically made as a guide for hiking and biking trips, has the opposite problem... It's hardcover, and it's kind of bulky. I mean, that's great, normally I'd be in favor of that... But if I'm going to be hiking for days or weeks (some of the trails in this book take over three weeks to complete according to the book), the last thing I'm going to want to do is carry this thing around. It's a little baffling that they'd choose this of all books to make hardcover. Honestly, though, I am probably not hiking (at least not for a multi-week trail... maybe for a few days in there, for the rest I'll take a train or rent a car), which is why I decided not to remove a star. But if you will be hiking, it may be something you'll want to consider.
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Reviewed in the United States on November 9, 2025
D
Deshrek
Alexandria, US
★★★★★ 5
Very beautiful book
Format: Hardcover
It’s not only a tour guide but rather a detail record of the Camino de Santiago history book and the pictures inside this book look so beautiful you may only find in specialized photo albums.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on January 14, 2026
T
The Indie Reviewer
Dallas, US
★★★★★ 5
Wonderful resource
Format: Hardcover
This spectacular pilgrim guide title Walking the Camino de Santiago, is an excellent production that provides helpful guidance on anything a pilgrim would need to know prior to making this well-known pilgrimage via some not-so-well-known routes and tips. This book stands out in excellence with its simplicity and yet thoroughness in providing chapters on the possible eight pilgrimage routes with history on each one. It provides tips and practical information on things to check out as part of the geographical and cultural landmarks, food, accommodations, etc. The illustrations and photographs in this book make it a stunning work of art and resource. Anyone considering doing this pilgrimage/ retreat would benefit from this book. If nothing else, this book can be gifted to someone considering doing the Camino, and it would make an excellent coffee table conversation starter.
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Reviewed in the United States on December 27, 2025

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