SKU: 11377893362

CD1d Recombinant Rabbit mAb (S-2686-138)

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Description

CD1d Recombinant Rabbit mAb (S-2686-138)Product Specification Host Rabbit Antigen CD1d Synonyms Antigen presenting glycoprotein CD1d; R3G1; CD1D Immunogen Recombinant Protein Location Cell membrane, Endoplasmic reticulum membrane Accession P15813 Clone Number S 2686 138 Antibody Type Recombinant mAb Isotype IgG Application WB Reactivity Hu Positive Sample Jurkat, Molt 4 Purification Protein A Concentration 0. 5 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS,

Product Specification


Host Rabbit
Antigen CD1d
Synonyms Antigen-presenting glycoprotein CD1d; R3G1; CD1D
Immunogen Recombinant Protein
Location Cell membrane, Endoplasmic reticulum membrane
Accession P15813
Clone Number S-2686-138
Antibody Type Recombinant mAb
Isotype IgG
Application WB
Reactivity Hu
Positive Sample Jurkat, Molt-4
Purification Protein A
Concentration 0.5 mg/ml
Conjugation Unconjugated
Physical Appearance Liquid
Storage Buffer

PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300

Stability & Storage

12 months from date of receipt / reconstitution, -20 °C as supplied

Dilution


application dilution species
WB 1:1000 Hu

Background

CD1d is a transmembrane glycoprotein that belongs to the group 2 CD1 family of non-classical MHC class I-like antigen-presenting molecules, expressed on dendritic cells, thymocytes, hepatocytes and many other tissues; it forms a heterodimer with β2-microglobulin, folds into a deep, hydrophobic groove made up of A′ and F′ pockets that cradle lipid tails while exposing the glycosyl headgroups of self or microbial glycolipids, and delivers these antigens to the invariant T-cell receptor of CD1d-restricted natural killer T (iNKT) cells, thereby rapidly triggering large bursts of cytokines such as IFN-γ and IL-4 that shape innate and adaptive immune responses against infections, cancer, and autoimmune diseases .

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SKU: 11377893362

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