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Description
Synapsin-1 Recombinant Rabbit mAb (S-550-7)Product Specification Host Rabbit Antigen Synapsin 1 Synonyms Brain protein 4. 1, Synapsin I, SYN1 Immunogen Synthetic Peptide Accession P17600 Clone Number S 550 7 Antibody Type Recombinant mAb Application WB, IHC P, IP Reactivity Hu, Ms, Rt Predicted Reactivity Bv, Dg Purification Protein A Concentration 0. 5 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS, 40% Glycerol, 0. 05%BSA, 0. 03% Proclin 300 Stability & Storage
Product Specification
| Host | Rabbit |
| Antigen | Synapsin-1 |
| Synonyms | Brain protein 4.1, Synapsin I, SYN1 |
| Immunogen | Synthetic Peptide |
| Accession | P17600 |
| Clone Number | S-550-7 |
| Antibody Type | Recombinant mAb |
| Application | WB, IHC-P, IP |
| Reactivity | Hu, Ms, Rt |
| Predicted Reactivity | Bv, Dg |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05%BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | |
| IP | 1:50 | |
| IHC | 1:2000 |
Background
The synapsin I protein is a member of the synapsin family that are neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Pathways leading to the induction of human eS6 phosphorylation have been found to enhance IL-8 protein synthesis. This mechanism is dependent on A/U-rich proximal sequences (APS) found in the 3'UTR of IL-8 immediately after the stop codon. Synapsin I plays important roles in synapse formation where they specifically minimize depletion of the neurotransmitter at the inhibitory synapses by contributing to the anchoring of synaptic vesicles.
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