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Description
Mouse CD4, His tagProduct Specification Species Mouse Synonyms T cell differentiation antigen L3T4, T cell surface antigen T4 Leu 3 Accession P06332 Amino Acid Sequence Protein sequence(P06332, Lys27 Thr394, with C 10*His)
Product Specification
| Species | Mouse |
| Synonyms | T-cell differentiation antigen L3T4, T-cell surface antigen T4/Leu-3 |
| Accession | P06332 |
| Amino Acid Sequence | Protein sequence(P06332, Lys27-Thr394, with C-10*His) KTLVLGKEGESAELPCESSQKKITVFTWKFSDQRKILGQHGKGVLIRGGSPSQFDRFDSKKGAWEKGSFPLIINKLKMEDSQTYICELENRKEEVELWVFKVTFSPGTSLLQGQSLTLTLDSNSKVSNPLTECKHKKGKVVSGSKVLSMSNLRVQDSDFWNCTVTLDQKKNWFGMTLSVLGFQSTAITAYKSEGESAEFSFPLNFAEENGWGELMWKAEKDSFFQPWISFSIKNKEVSVQKSTKDLKLQLKETLPLTLKIPQVSLQFAGSGNLTLTLDKGTLHQEVNLVVMKVAQLNNTLTCEVMGPTSPKMRLTLKQENQEARVSEEQKVVQVVAPETGLWQCLLSEGDKVKMDSRIQVLSRGVNQTGGGGSHHHHHHHHHH |
| Expression System | HEK293 |
| Molecular Weight | Theoretical:42.9kDa Actual:53-60kDa |
| Purity | ＞95% by SDS-PAGE |
| Endotoxin | <1EU/μg |
| Tag | His Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, 1mM EDTA, pH7.4. |
| Reconstitution | Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation. |
| Stability & Storage | 12 months from date of receipt, -20 to -70 °C as supplied. 6 months, -20 to -70 °C under sterile conditions after reconstitution. 1 week, 2 to 8 °C under sterile conditions after reconstitution. Please avoid repeated freeze-thaw cycles. |
Background
In molecular biology, CD4 (cluster of differentiation 4) is a glycoprotein that serves as a co-receptor for the T-cell receptor (TCR). CD4 is found on the surface of immune cells such as T helper cells, monocytes, macrophages, and dendritic cells. CD4 is a co-receptor of the T cell receptor (TCR) and assists the latter in communicating with antigen-presenting cells. The TCR complex and CD4 bind to distinct regions of the antigen-presenting MHC class II molecule. The extracellular D1 domain of CD4 binds to the β2 region of MHC class II. The resulting close proximity between the TCR complex and CD4 allows the tyrosine kinase Lck bound to the cytoplasmic tail of CD4 to phosphorylate tyrosine residues of immunoreceptor tyrosine activation motifs (ITAMs) on the cytoplasmic domains of CD3 to amplify the signal generated by the TCR.
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4.1 ★★★★★
Based on 16 reviews
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Product Reviews
★★★★★ 5
Pillowd
Color: Blue, Size: Queen Size Set of 2
They are huge and very fluffy queen size pillows, and they’re so comfortable. I’m actually laying on one right now.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 29, 2026
★★★★★ 5
Helps you get a good night's rest
Color: Blue, Size: Queen Size Set of 2
These are my favorite pillows. I've had so much neck pain and headaches in the morning. This all stopped once I started using them. They hold up their shape and seem like they are good quality. My husband kept trying to steal my pillow, so I had to order him his own. You won't be disappointed in these pillows, and you'll get much better sleep.
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Reviewed in the United States on May 26, 2026
★★★★★ 4
Very soft!
Color: Blue, Size: Queen Size Set of 2
I like the softness of these pillows. They are too bulky for me but my husband loves his. I’ve been using a flat pillow for too long. I may just need to adjust to it.
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Reviewed in the United States on May 17, 2026
★★★★★ 5
BUY THEM NOW!! the search is OVER! 🥳
Color: Blue, Size: Queen Size Set of 2, Color: Blue, Size: Queen Size Set of 2
pillow whore here 🤭 and I very rarely find anything worth writing a 5 star review for but let me just save you the time of searching anymore for the PERFECT pillow!!! BUY THEM! 😍 I promise you will NOT be disappointed!! I have spend thousands on pillows over the years, trying to find the perfect pillows... As someone who suffers from debilitating chronic pain and who has had multiple neck and back surgeries I'm very particular about pillows & have such a hard time finding one's that are comfortable, not too hard, not too soft but also offer great support. I FINALLY found them 🥹 and my hubby is Italian and stays hot but gets even hotter when he sleeps so finding an authentic cooling pillow has seemed impossible UNTIL now!! Just wow!! Now Im adding more to my cart while they are still 70% off 🥳🤩
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Reviewed in the United States on May 8, 2026
★★★★★ 3
no thank you
Color: Blue, Size: Queen Size Set of 2
while they look great, they are not soft. I can not sleep with them. Woke with a headache.
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Reviewed in the United States on May 7, 2026