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Description
Human & Monkey CXCL10(serum/plasma) OneStep ELISA KitProduct Specification Antigen CXCL10 Immunogen Recombinant Protein Antibody Type Recombinant mAb Reactivity Hu, Mk Purification Protein A Stability & Storage 12 months from date of receipt reconstitution, 2 to 8'C as supplied. Kit Precision Intra assay: 4. 7% Inter assay: 8. 1% Sample type Serum; Plasma Assay type Sandwich (quantitative) Sensitivity 1. 222 pg mL Range 2. 34 pg mL 150 pg mL Recovery Serum: 111% Plasma: 100% Assay time 60 minutes
Product Specification
| Antigen | CXCL10 |
| Immunogen | Recombinant Protein |
| Antibody Type | Recombinant mAb |
| Reactivity | Hu, Mk |
| Purification | Protein A |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8'C as supplied. |
Kit
| Precision | Intra-assay: 4.7%； Inter-assay: 8.1% |
| Sample type | Serum; Plasma |
| Assay type | Sandwich (quantitative) |
| Sensitivity | 1.222 pg/mL |
| Range | 2.34 pg/mL – 150 pg/mL |
| Recovery | Serum: 111% Plasma: 100% |
| Assay time | 60 minutes |
| Species reactivity | Hu; Mk |
Background
CXCL10 is a small signaling protein classified as a chemokine. It is primarily produced by cells like macrophages and fibroblasts in response to interferon-gamma. Its main function is to act as a chemoattractant, guiding immune cells to sites of inflammation or infection. Specifically, CXCL10 binds to a receptor called CXCR3, which is found on the surface of activated T cells and natural killer (NK) cells. This interaction is crucial for mounting an effective immune response against viruses and intracellular pathogens. Consequently, CXCL10 plays a significant role in autoimmune diseases, chronic inflammation, and anti-tumor immunity. Its expression is often used as a biomarker for Th1-type immune responses. In summary, CXCL10 is a key mediator that recruits specific immune cells to coordinate the body's defense mechanisms.
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