SKU: 3381406664

Human AACT, his tag

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Description

Human AACT, his tagProduct Specification Species Human Synonyms Cell growth inhibiting gene 24 25 protein,Serpin A3,AACT Accession P01011 Amino Acid Sequence Protein sequence (P01011, His24 Ala423, with C 10*His)

Product Specification


Species Human
Synonyms Cell growth-inhibiting gene 24/25 protein,Serpin A3,AACT
Accession P01011
Amino Acid Sequence

Protein sequence (P01011, His24-Ala423, with C-10*His) HPNSPLDEENLTQENQDRGTHVDLGLASANVDFAFSLYKQLVLKAPDKNVIFSPLSISTALAFLSLGAHNTTLTEILKGLKFNLTETSEAEIHQSFQHLLRTLNQSSDELQLSMGNAMFVKEQLSLLDRFTEDAKRLYGSEAFATDFQDSAAAKKLINDYVKNGTRGKITDLIKDLDSQTMMVLVNYIFFKAKWEMPFDPQDTHQSRFYLSKKKWVMVPMMSLHHLTIPYFRDEELSCTVVELKYTGNASALFILPDQDKMEEVEAMLLPETLKRWRDSLEFREIGELYLPKFSISRDYNLNDILLQLGIEEAFTSKADLSGITGARNLAVSQVVHKAVLDVFEEGTEASAATAVKITLLSALVETRTIVRFNRPFLMIIVPTDTQNIFFMSKVTNPKQAGGGGSHHHHHHHHHH

Expression System HEK293
Molecular Weight Predicted MW: 47 kDa Observed MW: 55-72 kDa
Purity >95% by SDS-PAGE
Tag with C-10*His
Physical Appearance Lyophilized Powder
Storage Buffer Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, pH7.4.
Reconstitution Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation.
Stability & Storage

12 months from date of receipt, -20 to -70 °C as supplied. 6 months, -20 to -70 °C under sterile conditions after reconstitution. 1 week, 2 to 8 °C under sterile conditions after reconstitution. Please avoid repeated freeze-thaw cycles.

Background

Alpha 1-antichymotrypsin (symbol α1AC, A1AC, or a1ACT) is an alpha globulin glycoprotein that is a member of the serpin superfamily. In humans, it is encoded by the SERPINA3 gene. Alpha 1-antichymotrypsin inhibits the activity of certain enzymes called proteases, such as cathepsin G that is found in neutrophils, and chymases found in mast cells, by cleaving them into a different shape or conformation. This activity protects some tissues, such as the lower respiratory tract, from damage caused by proteolytic enzymes. This protein is produced in the liver, and is an acute phase protein that is induced during inflammation. Deficiency of this protein has been associated with liver disease.

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Exchange/Return Notes
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SKU: 3381406664

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4.8 ★★★★★
Based on 28 reviews
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Product Reviews
N
Verified Purchase
Nancy Dodson-Houck
Lake Worth, US
★★★★★ 5
My dogs favorite
Size: Small, Color: Bunny
I need this toy! It is my dogs favorite. She even takes this on walks. Ive replaced this on 3 times because it was “eaten” by my daughters dog. I keep it put up and Georgia constantly goes to the spot I keep it and is expecting me to give it to her. Please restock soon
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 29, 2026
E
Verified Purchase
Ema
Carnegie, US
★★★★★ 4
My doggo's go-to toy!
It's not the most durable of toys (she's on her third in five years) but I will buy her as many as she needs because she is OBSESSED with it!
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on December 5, 2024
A
Verified Purchase
Amazon Customer
New York, US
★★★★★ 5
Nice
Size: Small, Color: Bunny, Size: Small, Color: Bunny
Cute, dog loves it
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 5, 2026
R
Verified Purchase
Ranger Sarge
Battle Creek, US
★★★★★ 1
Defective toy and inconsistent quality.
Size: X-Large, Color: Raccoon, Size: X-Large, Color: Raccoon
My initial review was 5 stars based on my experience with a previous order (blue raccoon) and the fact my puppy was immediately interested in it. However, I did not give it to her to play with until this past Friday (May 21, 2026) because she had the first one I bought. In a matter of 2 days the seam on the back and at the base of the head unraveled and all of the stuffing was scattered all over the room. I thought I’d found some good, high quality, toys for her but apparently this one was defective because the first one had had a lot of use and I’d still in decent shape. This is too much money to pay for a dog toy that only lasts a day or two so be advised they aren’t all good.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on April 11, 2026
J
Verified Purchase
J. Bush
Chelsea, US
★★★★★ 5
Bigger, louder, crinklier, softer, than expected!
Size: X-Large, Color: Rabbit
My dog was gifted a collection of used toys and he really likes a very long stuffed pig which, unfortunately, another dog that is a destructive chewer, totally destroyed. I decided to break down and buy him another long stuffed toy today and since he's always blissfully watching rabbits in the yard and neighborhood I chose the rabbit version. This thing is huge which is great for him- he's 62 lbs and 7 months old and only half grown. He loves it, it has multiple LOUD squeakers, lots of crinkly spots, and fun ears/legs to grab hold off. He's a big fan and it's made with K9 Tuff Guard which LASTS. Super soft and easy to wash. Update after 2 months- easy to wash and looks new after a washing. very durable so far, standing up to indoor and outdoor use. He is not a destructive chewer but whips them around, tramples on them, steps on them while running top speed and chomps on the annoying squeaker for hours. one squeaker has a hole and its tune is now slightly muted (thank god)
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on August 24, 2019

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