Pay in installments of $31.25 with
,
and
Shipping Estimate
USA
- USA
- CAN
- USA
- CAN
Ships within 48 hours · Estimated delivery Aug 14 - Aug 19
Promo Codes Available:
For Your Every Summer RSVP, with Code: SUMMER15
Description
Pacific Blue Rat Anti-Mouse Ly-6C Antibody (S-R523)Product Specification Host Rat Antigen Ly 6C Synonyms Lymphocyte antigen 6C1; Ly 6C1; Ly6c1 Location Cell membrane Accession P0CW02 Clone Number S R523 Antibody Type Rat mAb Isotype IgG2c,k Application FCM Reactivity Ms Positive Sample C57BL 6 mouse bone marrow Purification Protein G Concentration 0. 2 mg ml Conjugation Pacific Blue Physical Appearance Liquid Storage Buffer PBS, 1% BSA, 0. 3% Proclin 300 Stability & Storage 12 months from date of
Product Specification
| Host | Rat |
| Antigen | Ly-6C |
| Synonyms | Lymphocyte antigen 6C1; Ly-6C1; Ly6c1 |
| Location | Cell membrane |
| Accession | P0CW02 |
| Clone Number | S-R523 |
| Antibody Type | Rat mAb |
| Isotype | IgG2c,k |
| Application | FCM |
| Reactivity | Ms |
| Positive Sample | C57BL/6 mouse bone marrow |
| Purification | Protein G |
| Concentration | 0.2 mg/ml |
| Conjugation | Pacific Blue |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 1% BSA, 0.3% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied |
Dilution
| application | dilution | species |
| FCM | 5μl per million cells in 100μl volume | Ms |
Background
Ly-6C is a glycosylphosphatidylinositol-anchored cell-surface protein belonging to the Ly-6/uPAR/α-neurotoxin superfamily, selectively expressed on murine monocyte and T-cell subsets where it serves as a dynamic lineage and activation marker—its high level on pro-inflammatory “classical” monocytes (CD11b⁺Ly-6C^hi) enables their recruitment via CCR2 to inflamed tissues, whereas Ly-6C^lo monocytes patrol vasculature and replenish resident macrophages, and transient up-regulation on CD8⁺ T cells correlates with effector differentiation; structurally it forms a three-finger α-helical bundle that can laterally associate with lipid rafts and signaling partners such as T-cell receptor or integrin complexes to modulate calcium flux, cytokine release, and adhesion, thereby critically steering innate–adaptive immune crosstalk in infections, autoimmunity, and cardiovascular disease.
Shipping Notes
- Free Standard Shipping on $100+ Orders to the USA.
- Except Preorder products are shipped in 48 hours.
- Delivery to the USA:
- Standard Shipping : 3-10 business days
- If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
- Final sale items are not eligible for returns or exchanges.
- To process your return/exchange, please contact us at [email protected]
- Please click here for more details>>> Return & Exchange Policy