SKU: 35219592449

Pacific Blue Rat Anti-Mouse CD226 Antibody (S-R625)

$144.00 $160.00
Save 10%
No.2 Bestseller on watersyst.com >

Pay in installments of $40.00 with ShopPay, AfterPay and Klarna

Shipping Estimate
USA
  • USA
  • CAN

Ships within 48 hours · Estimated delivery Aug 21 - Aug 26

Promo Codes Available:

For Your Every Summer RSVP, with Code: SUMMER15

Description

Pacific Blue Rat Anti-Mouse CD226 Antibody (S-R625)Product Specification Host Rat Antigen CD226 Synonyms CD226 antigen; Platelet and T cell activation antigen 1; Pta1; Cd226 Location Cell membrane Accession Q8K4F0 Clone Number S R625 Antibody Type Rat mAb Isotype IgG2b,k Application FCM Reactivity Ms Positive Sample C57BL 6 mouse splenocytes Purification Protein G Concentration 0. 2 mg ml Conjugation Pacific Blue Physical Appearance Liquid Storage Buffer PBS, 1% BSA, 0. 3% Proclin 300 Stability &

Product Specification


Host Rat
Antigen CD226
Synonyms CD226 antigen; Platelet and T-cell activation antigen 1; Pta1; Cd226
Location Cell membrane
Accession Q8K4F0
Clone Number S-R625
Antibody Type Rat mAb
Isotype IgG2b,k
Application FCM
Reactivity Ms
Positive Sample C57BL/6 mouse splenocytes
Purification Protein G
Concentration 0.2 mg/ml
Conjugation Pacific Blue
Physical Appearance Liquid
Storage Buffer

PBS, 1% BSA, 0.3% Proclin 300
Stability & Storage

12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

Dilution


application dilution species
FCM 5μl per million cells in 100μl volume Ms

Background

CD226, also known as DNAM-1, is a transmembrane glycoprotein in the immunoglobulin superfamily that functions as a key co-stimulatory receptor on T cells, NK cells, monocytes, and platelets, where it binds the nectin-family ligands CD155 and CD112 to trigger phosphorylation of its intracellular tyrosine and serine residues, thereby recruiting LFA-1 and activating Src, PI3K-AKT, VAV1-ERK, and PLCγ2 signaling cascades that enhance immune synapse formation, cytotoxic granule release, and production of IFN-γ and other cytokines, thus promoting antiviral and antitumor immunity; its expression correlates with improved outcomes in cancer immunotherapy, while its genetic polymorphisms or down-regulation are linked to autoimmune diseases and tumor immune evasion, making CD226 an emerging target for immunomodulatory therapies.

Shipping Notes
  • Free Standard Shipping on $100+ Orders to the USA.
  • Except Preorder products are shipped in 48 hours.
  • Delivery to the USA:
  1. Standard Shipping : 3-10 business days
  • If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
  • We offer a 30-day return/exchange service after receiving.
  • Final sale items are not eligible for returns or exchanges.
  • To process your return/exchange, please contact us at [email protected]
  • Please click here for more details>>> Return & Exchange Policy
SKU: 35219592449

Discover Niche Categories That Outsell

Top-Converting Item to Boost Your Average Order

4.1 ★★★★★
Based on 25 reviews
Sort
Highest Rating
Newest First
Oldest First
Product Reviews
J
Verified Purchase
Jennifer Stenson
Lexington, US
★★★★★ 5
Perfect for active dogs
This is a must-have if your dog loves to fetch. It throws the ball far with very little effort and keeps your hands clean—no more slobbery chuckit balls. Lightweight, durable, and makes playtime much more fun (and less tiring for me!).
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on April 9, 2026
J
Verified Purchase
John J
Belleville, US
★★★★★ 5
Way better than the M size for us
Like most people that have dogs I first went with the M size or Tennis ball size (about 2.5") chuckit for my 65-70 lbs Lab. After having that for a while and my dogs' evolution from liking to chase the ball to wanting to catch it, I started seeing how the M size could cause some life threating problems for my pup. I was on the fence for several weeks when I came across this option that included a 3" ultra ball as well as a 3" fuzzy tennis ball like ball. These balls can fly so much farther with less effort and my furry friend seeming to like them more than the 2.5 inch. It also seems to fit their mouth better allowing them to enjoy 'the game' (you lost by the way) much more. If you have a larger dog or your dog has a big mouth, please trust me when I say skip the 2.5" M size balls. You and your dog will haves much more fun with this 3" size
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on December 10, 2024
D
Verified Purchase
Donna Sue
Grantham, US
★★★★★ 5
Chuck it ball launcher
This is great! I have a blue healer that loves it. She will play fetch with the ball all day long. The launcher is easier on my shoulder. I can throw the ball twice as far and when she brings the ball back I can grab it with the launcher without touching a spit covered ball. Awesome buy!
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 2, 2025
S
Stephanie Straub
Los Angeles, US
★★★★★ 5
Good find
Chuckit products are great, and was glad to find this for the Pitties that I pet sit for
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on October 23, 2025
S
Verified Purchase
S. McCartin
Massapequa, US
★★★★★ 5
good for puppys young dogs, handle is separate, locking carabiners on both ends
Color: Orange, Size: 30FT
This is a good sturdy leash but probably wouldn't stand up to a conscientious chewer if your dogo has that bad habit. I like this one because the handle is separate so it can be used both as a tie out lead and as a regular lead. I also like the "locking" carabiners that should not open accidentally. I bought the thirty foot version because my new puppy loves to go outside then refuse to come back in or let me catch him when I need him to come inside (not catching me silly Hooman). When he's bigger I won't be so concerned about him being outside alone but since I'm in a sort of rural area, we have the occasional fox and hawk around when the sun goes down. Not too much to worry about in the way of pests but every puppy parent has an obligation to protect their young'un till they gain some wisdom. I have stairs in the back of the house, the way this is made I can attach it to the banister easily so I don't even need one of those tie stakes that bury in the ground. The price wasn't bad, the hardware looks sturdy and should last awhile. I just also bought the fifteen foot version, same quality as the thirty foot product I like that the handle is separate so it can be used as a tie down or a leash easily. My only big wish would perhaps be some more color choices, the orange is nice for visibility a yellow would be nice and then maybe some other colors like red/purple would be good as well. The thickness of the rope means that it doesn't "easily" get tangled into a giant knot. I leave the back door open and puppers can go in and out as he likes but he also sometimes runs around in the living room and thus far haven't had any large tangles to unwrap. He did manage to get the leash caught around a piece of tree branch that was on the ground (and complained loudly) but that was only because the branch was too heavy for him to drag the lead off of by himself. These leads are worth the money, I will likely buy a couple more to keep in the vehicle and other locations besides home.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on April 29, 2026

recommand products

Chow Chow v2s - Luxury Necklace
39.95
Singapura v3 - Bangle Bracelet
39.95
Australian Shepherd v2s - Luxury Necklace
39.95
Boykin Spaniel v2s - Luxury Necklace
39.95
Bernese Mountain Dog v2s - Luxury Necklace
39.95