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Description
LYPD8 Fc Chimera Protein, HumanProduct Specification Species Human Synonyms LYPD8, LY6, PLAUR domain containing 8 Accession Q6UX82 Amino Acid Sequence Leu20 Asn215, with C terminal Human IgG1 Fc
Product Specification
| Species | Human |
| Synonyms | LYPD8, LY6, PLAUR domain containing 8 |
| Accession | Q6UX82 |
| Amino Acid Sequence | Leu20-Asn215, with C-terminal Human IgG1 Fc LSCVQCNSWEKSCVNSIASECPSHANTSCISSSASSSLETPVRLYQNMFCSAENCSEETHITAFTVHVSAEEHFHFVSQCCQGKECSNTSDALDPPLKNVSSNAECPACYESNGTSCHGKPWKCYEEEQCVFLVAELKNDIESKSLVLKGCSNVSNATCQFLSGENKTLGGVIFRKFECANVNSLTPTSAPTTSHNIEGRMDPKSSDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK |
| Expression System | HEK293 |
| Molecular Weight | 60-95kDa |
| Purity | >95% by SDS-PAGE |
| Endotoxin | <0.1EU/μg |
| Conjugation | Unconjugated |
| Tag | Human Fc Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | PBS, pH7.4 |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles. |
| Reference | 1、Okumura R. et al. (2020) Lypd8 inhibits attachment of pathogenic bacteria to colonic epithelia. Mucosal Immunol. 13: 75-85. |
Background
Lypd8 is a highly N-glycosylated glycosylphosphatidylinositol-anchored protein that is highly expressed on colonic IECs and constitutively shed into the intestinal lumen. Lypd8 inhibits the invasion of colonic epithelia by flagellated commensal bacteria such as Proteus mirabilis and E. coli belonging to Enterobacteriaceae family by suppressing their motility via flagella binding. However, it remains unclear whether Lypd8 has a protective function against pathogenic bacteria, including pathogenic E. coli, Salmonella, Shigella, and Citrobacter, many of which belong to the family Enterobacteriaceae.
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4.5 ★★★★★
Based on 9 reviews
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Product Reviews
★★★★★ 5
Well built, minimal and modern
Color: Moss Green, Size: 9.5in x 7.9in
Bought this to help build routine for my son, rather than spending inordinate amounts of time looking for his things. It’s quality built with a sleek modern look. Very handsome.
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Reviewed in the United States on February 8, 2026
★★★★★ 5
Excellent tray
Color: Sand Brown, Size: 9.5in x 7.9in
This is an exceptionally high-quality tray. The design was well thought out and it looks amazing. I keep it in my top dresser drawer to organize extra cards for my wallet, my watch, cufflinks, and other items. I can’t say enough about the high level of quality. It stays in place, has great storage and very reasonably priced I thought.
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Reviewed in the United States on August 15, 2025
★★★★★ 4
Good purchase
Color: Sand Brown, Size: 9.5in x 7.9in
Bought for my husbands desk, it looks nice and good quality for the price
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Reviewed in the United States on January 7, 2026
★★★★★ 5
Luxurious
Color: Sand Brown, Size: 9.5in x 7.9in
Firstly, I was very impressed by the packaging and attention to detail, from the box to the lovely wrapping. I purchased the brown and the tray is beautiful with the two-tone. I love the tree imprint on the inside. It looks very rich and the leather has a great feel to it. I also like that the logo was imprinted at the bottom/back. This would make a great gift. Great product!
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Reviewed in the United States on August 1, 2025
★★★★★ 5
Luxury Organization
Color: Pebble Black, Size: 9.5in x 7.9in
Keep your keys, wallet, and all other every day carry items in one, high quality location. Very nice material and build quality that accessorizes my dresser perfectly. The size is appropriate for everything that belongs in your pockets. Overall the best value for your $ I’ve seen, especially if you can catch a discount.
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Reviewed in the United States on March 30, 2026