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Description
Siglec-4a His Tag Protein, HumanProduct Specification Species Human Synonyms MAG Accession P20916 1 Amino Acid Sequence Gly20 Pro516, with C terminal 10*His
Product Specification
| Species | Human |
| Synonyms | MAG |
| Accession | P20916-1 |
| Amino Acid Sequence | Gly20-Pro516, with C-terminal 10*His GHWGAWMPSSISAFEGTCVSIPCRFDFPDELRPAVVHGVWYFNSPYPKNYPPVVFKSRTQVVHESFQGRSRLLGDLGLRNCTLLLSNVSPELGGKYYFRGDLGGYNQYTFSEHSVLDIVNTPNIVVPPEVVAGTEVEVSCMVPDNCPELRPELSWLGHEGLGEPAVLGRLREDEGTWVQVSLLHFVPTREANGHRLGCQASFPNTTLQFEGYASMDVKYPPVIVEMNSSVEAIEGSHVSLLCGADSNPPPLLTWMRDGTVLREAVAESLLLELEEVTPAEDGVYACLAENAYGQDNRTVGLSVMYAPWKPTVNGTMVAVEGETVSILCSTQSNPDPILTIFKEKQILSTVIYESELQLELPAVSPEDDGEYWCVAENQYGQRATAFNLSVEFAPVLLLESHCAAARDTVQCLCVVKSNPEPSVAFELPSRNVTVNESEREFVYSERSGLVLTSILTLRGQAQAPPRVICTARNLYGAKSLELPFQGAHRLMWAKIGPGGGSGGGSHHHHHHHHHH |
| Expression System | HEK293 |
| Molecular Weight | 80-95 kDa(Reducing) |
| Purity | ＞95% by SDS-PAGE |
| Endotoxin | <0.1EU/μg |
| Conjugation | Unconjugated |
| Tag | His Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | PBS, pH7.4 |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles. |
Background
Sialic acid-binding immunoglobulin-like lectins (Siglecs) are cell surface receptors of the I-type lectin family that are expressed on innate immune cells and bind to sialylated and non-sialylated ligands. Myelin-Associated Glycoprotein (MAG), also known as Siglec-4a, is a type I transmembrane glycoprotein belonging to the Siglec family, a subgroup of the Ig superfamily. It is selectively expressed by myelinating cells including Schwann cells in the peripheral nervous system (PNS) and oligodendrocytes in the central nervous system (CNS). It is encoded by a single gene that is conserved among vertebrates. It is composed of an extracellular segment containing five Ig-like domains, a single transmembrane segment, and a cytoplasmic domain. Mature MAG exists as two isoforms, termed S-MAG (short) and L-MAG (long), due to alternative splicing of the cytoplasmic domain.
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4.7 ★★★★★
Based on 17 reviews
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Product Reviews
★★★★★ 5
Excellent Air filter - Easy installation.
Style: BE-743 1-Pack
Excellent AC and Heater Cabinet odor defense air filter. I noticed immediately the smell coming out of the vents was fresher and the musty smell that was coming from the vents was crisper and cleaner. Very easy installation that you can do yourself and don’t need to pay a shop to do. The price is one of the best online and coms in quickly. It’s very sturdy, filter quality is excellent and it definitely improves the air quality and flow in your car. Fits perfectly like any OEM filter, this is a great buy for the price of an installation that will take you Les then 10 minutes to do yourself.
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Reviewed in the United States on May 21, 2026
★★★★★ 5
Great filter and easy installation
Style: BE-159 1-Pack, Style: BE-159 1-Pack
For my 2016 Hyundai Sonata Hybrid Limited. I cannot believe I paid so much more for a brand-name filter that does the same thing as this one. It is made of the same material as the dealer one I took out. Very easy to install, cant believe I paid for this to be done in the past with oil changes. Requires no tools and did not get dirty at all. No mechanical skills needed, especially if you run into trouble and can use YouTube.
PROS
- great quality, cannot tell that it is after-market
- very professionally made, not irregularities seen
- excellent fit in position, no adjustment needed
- very easy to install, cannot believe I paid to have this done in the past
- no mechanical skills needed to install
- great price compared to what big name productions want for the same thing
- cannot tell the difference in air quality between this and the dealer filter I took out
- removes outside odor completely
- did not require tools are getting dirty
CONS
- None
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Reviewed in the United States on May 30, 2026
★★★★★ 5
Fits perfect and works as designed. Flows like OEM and looks well made.
Style: BE-553B 1-Pack
This filter is very comparable to the stock filter. Fits the BMW G20 just like OEM. I would not say it is two times "heavier" as advertised on the box, but it is very comparable to stock. It's the same weight and similar construction. BMW has a very robust cabin filter. This will be my go to. I did purchase another aftermarket cabin filter that fit well, but was thin, flimsy and had a bad chemical odor. This one is fine and airflow is the same as OEM. I change them every year or so. I don't worry too much about longevity with cabin filters personally.
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Reviewed in the United States on May 15, 2026
★★★★★ 4
Good quality but it was slightly longer than original and needed modification.
Style: BE-182 1-Pack
Bought this cabin filter for a 2023 Acura TLX. While the filter seems to be made of quality material, it was just a little too long (about a 1/16 of an inch, so I had to trim it to make it fit so the cover would fit snug. I was able to do that without compromising the filter itself. But this might be an issue for some people
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Reviewed in the United States on May 8, 2026
★★★★★ 5
Fits my Chevy 2021 Bolt Premier perfectly.
Style: BE-966 1-Pack
Installation was a breeze, fir nicely and the air in teh car now smells fresh and clean. The old filter has developed a musty smell so this new one is great. Had it replaced in under 3 minutes.
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Reviewed in the United States on May 18, 2026