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Description
CXCR5 Recombinant Rabbit mAb (SDT-351-24)Product Specification Host Rabbit Antigen CXCR5 Synonyms C X C chemokine receptor type 5, BLR1, MDR15, CD185 Immunogen Synthetic Peptide Location Cell membrane Accession P32302 Clone Number SDT 351 24 Antibody Type Recombinant mAb Application IHC P, ICC, FCM Reactivity Hu Purification Protein A Concentration 0. 5 mg ml Tag N A Physical Appearance Liquid Storage Buffer PBS, 40% Glycerol, 0. 05% BSA, 0. 03% Proclin 300 Stability & Storage 12 months from
Product Specification
| Host | Rabbit |
| Antigen | CXCR5 |
| Synonyms | C-X-C chemokine receptor type 5, BLR1, MDR15, CD185 |
| Immunogen | Synthetic Peptide |
| Location | Cell membrane |
| Accession | P32302 |
| Clone Number | SDT-351-24 |
| Antibody Type | Recombinant mAb |
| Application | IHC-P, ICC, FCM |
| Reactivity | Hu |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Tag | N/A |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| IHC-P | 1:5000 | |
| ICC | 1:100 | |
| FCM | 1:500 |
Background
CXCR5 is the receptor for the chemokine CXCL13, the chemokine important for secondary lymphoid tissue orchestration and lymphoid neogenesis. CXCL13 is constitutively expressed in secondary lymphoid tissue primarily by follicular dendritic cells in the spleen, lymph nodes, tonsils, and Peyer's patches, whereas CXCR5 is highly expressed in mature B lymphocytes and a subpopulation of follicular B helper T cells (Tfh). CXCL13 and its receptor CXCR5 are essential for trafficking B cells and homing B cells to lymphoid tissues and for the embryonic development of the majority of lymph nodes and Peyer's patches.
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Exchange/Return Notes
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