Pay in installments of $73.12 with
,
and
Shipping Estimate
USA
- USA
- CAN
- USA
- CAN
Ships within 48 hours · Estimated delivery Aug 11 - Aug 16
Promo Codes Available:
For Your Every Summer RSVP, with Code: SUMMER15
Description
HLA-DRB1 Recombinant Rabbit mAb,PBS Only (SDT-R253)Product Specification Host Rabbit Antigen HLA DRB1 Synonyms Human leukocyte antigen DRB1 (HLA DRB1) Location Cell membrane, Endoplasmic reticulum membrane Accession P01911 Clone Number SDT R253 Antibody Type Recombinant mAb Application WB, IHC P, ICC Reactivity Hu Purification Protein A Concentration 1 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS Stability & Storage 12 months from date of receipt reconstitution, 4 C as
Product Specification
| Host | Rabbit |
| Antigen | HLA-DRB1 |
| Synonyms | Human leukocyte antigen DRB1 (HLA-DRB1) |
| Location | Cell membrane, Endoplasmic reticulum membrane |
| Accession | P01911 |
| Clone Number | SDT-R253 |
| Antibody Type | Recombinant mAb |
| Application | WB, IHC-P, ICC |
| Reactivity | Hu |
| Purification | Protein A |
| Concentration | 1 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS |
| Stability & Storage | 12 months from date of receipt / reconstitution, 4 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:500 | |
| IHC | 1:4000 | |
| ICC | 1:250 |
Background
HLA class II histocompatibility antigen, DRB1 beta chain is a protein that in humans is encoded by the HLA-DRB1 gene. DRB1 encodes the most prevalent beta subunit of HLA-DR. DRB1 alleles, especially those encoding amino acid sequence changes at positions 11 and 13, are associated risk of rheumatoid arthritis. The protein encoded by this gene belongs to the HLA class II beta chain paralogues. The class II molecule is a heterodimer consisting of an alpha (DRA) and a beta chain (DRB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins to T helper cells. Class II molecules are constitutively expressed in professional antigen-presenting cells (APC: B lymphocytes, dendritic cells, macrophages), and could be induced in non-professional APCs. Mainly used for leukemia immunophenotyping, determination of primitive cell and monocyte differentiation.
Shipping Notes
- Free Standard Shipping on $100+ Orders to the USA.
- Except Preorder products are shipped in 48 hours.
- Delivery to the USA:
- Standard Shipping : 3-10 business days
- If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
- Final sale items are not eligible for returns or exchanges.
- To process your return/exchange, please contact us at [email protected]
- Please click here for more details>>> Return & Exchange Policy