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Description
Pacific Blue Mouse Anti-Mouse CX3CR1 Antibody (S-R597)Product Specification Host Mouse Antigen CX3CR1 Synonyms CX3C chemokine receptor 1; C X3 C CKR 1; mCX3CR1; Fractalkine receptor Location Cell membrane Accession Q9Z0D9 Clone Number S R597 Antibody Type Mouse mAb Isotype IgG2a,k Application FCM Reactivity Ms Positive Sample BALB c mouse splenocytes Purification Protein A Concentration 0. 5 mg ml Conjugation Pacific Blue Physical Appearance Liquid Storage Buffer PBS, 1% BSA, 0. 3% Proclin 300 Stability
Product Specification
| Host | Mouse |
| Antigen | CX3CR1 |
| Synonyms | CX3C chemokine receptor 1; C-X3-C CKR-1; mCX3CR1; Fractalkine receptor |
| Location | Cell membrane |
| Accession | Q9Z0D9 |
| Clone Number | S-R597 |
| Antibody Type | Mouse mAb |
| Isotype | IgG2a,k |
| Application | FCM |
| Reactivity | Ms |
| Positive Sample | BALB/c mouse splenocytes |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Pacific Blue |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 1% BSA, 0.3% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied |
Dilution
| application | dilution | species |
| FCM | 1μg per million cells in 100μl volume | Ms |
Background
CX3CR1 is a seven-transmembrane G-protein-coupled receptor expressed on monocytes, macrophages, dendritic cells, microglia and tissue-patrolling lymphocytes that serves as the exclusive receptor for the unique membrane-tethered or soluble chemokine CX3CL1 (fractalkine), thereby orchestrating leukocyte adhesion, chemotaxis and survival during development, homeostasis, viral and bacterial infections, inflammatory diseases such as atherosclerosis and rheumatoid arthritis, neuroinflammatory conditions including Alzheimer’s disease, and tumor progression or metastasis, while also acting as a co-receptor for respiratory syncytial virus entry into airway epithelium and modulating antiviral immunity via IL-10 induction.
Shipping Notes
- Free Standard Shipping on $100+ Orders to the USA.
- Except Preorder products are shipped in 48 hours.
- Delivery to the USA:
- Standard Shipping : 3-10 business days
- If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
- Final sale items are not eligible for returns or exchanges.
- To process your return/exchange, please contact us at [email protected]
- Please click here for more details>>> Return & Exchange Policy