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Description
Human IgG4 Fc , His tagProduct Specification Species Human Synonyms Ig gamma 4 chain C region, IGHG4 Accession P01861 Amino Acid Sequence Protein sequence(P01861, Glu99 Gly326, with C 10*His) ESKYGPPCPSCPAPEFLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSQEDPEVQFNWYVDGVEVHNAKTKPREEQFNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKGLPSSIEKTISKAKGQPREPQVYTLPPSQEEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSRLTVDKSRWQEGNVFSCSVMHEALHNHYTQKSLSLSLGGGGGSHHHHHHHHHH Expression System HEK293 Molecular Weight
Product Specification
| Species | Human |
| Synonyms | Ig gamma-4 chain C region, IGHG4 |
| Accession | P01861 |
| Amino Acid Sequence | Protein sequence(P01861, Glu99-Gly326, with C-10*His) ESKYGPPCPSCPAPEFLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSQEDPEVQFNWYVDGVEVHNAKTKPREEQFNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKGLPSSIEKTISKAKGQPREPQVYTLPPSQEEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSRLTVDKSRWQEGNVFSCSVMHEALHNHYTQKSLSLSLGGGGGSHHHHHHHHHH |
| Expression System | HEK293 |
| Molecular Weight | Theoretical:27.3kDa Actual:33kDa |
| Purity | >95% by SDS-PAGE |
| Endotoxin | <1EU/μg |
| Tag | with C-10*His |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, pH7.4. |
| Reconstitution | Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation. |
| Stability & Storage | 12 months from date of receipt, -20 to -70 °C as supplied. 6 months, -20 to -70 °C under sterile conditions after reconstitution. 1 week, 2 to 8 °C under sterile conditions after reconstitution. Please avoid repeated freeze-thaw cycles. |
Background
The fragment crystallizable region (Fc region) is the tail region of an antibody that interacts with cell surface receptors called Fc receptors and some proteins of the complement system. This property allows antibodies to activate the immune system. Fc binds to various cell receptors and complement proteins. In this way, it mediates different physiological effects of antibodies (detection of opsonized particles; cell lysis; degranulation of mast cells, basophils, and eosinophils; and other processes).
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4.8 ★★★★★
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★★★★★ 4
Read label good
Good so far
I think it would remove my dark spots
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Reviewed in the United States on February 1, 2026
★★★★★ 5
Excellent
Excellent product, good ingredients.
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Reviewed in the United States on May 21, 2026
★★★★★ 5
A Standout
This toner is a standout as it is infused with Centella Asiatica extract, which soothes irritation while gently exfoliating without causing dryness or redness. The watery texture absorbs quickly, leaving skin feeling refreshed and balanced. This toner helps improve skin texture and clarity.
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Reviewed in the United States on November 4, 2025
★★★★★ 5
Amazing
Amazing results, made the skin 1 color
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Reviewed in the United States on May 2, 2026
★★★★★ 5
Good, Cheap Makeup Wipes
Scent: Fragrance Free, Size: 25 Count (Pack of 1)
These wipes are a great value for the price and remove my everyday makeup—SPF, eyeliner, mascara, and lip products—without irritating my skin. They work efficiently and don’t require harsh rubbing. Compared to similar options, these are a better deal, and I plan to repurchase.
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Reviewed in the United States on April 15, 2026