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Description
Human Desmoglein 3, His tagProduct Specification Species Human Synonyms 130 kDa pemphigus vulgaris antigen (PVA), Cadherin family member 6, DSG3, CDHF6 Accession P32926 Amino Acid Sequence Protein sequence(Q29432, Arg54 Val380, with C 10*His)
Product Specification
| Species | Human |
| Synonyms | 130 kDa pemphigus vulgaris antigen (PVA), Cadherin family member 6, DSG3, CDHF6 |
| Accession | P32926 |
| Amino Acid Sequence | Protein sequence(Q29432, Arg54-Val380, with C-10*His) RGSNLTTHPLRNIKDLVYMGNITIGTPPQEFQVVFDTASSDLWVPSDFCTSPACSTHVRFRHLQSSTFRLTNKTFRITYGSGRMKGVVVHDTVRIGNLVSTDQPFGLSIEEYGFEGRIYDGVLGLNYPNISFSGAIPIFDKLKNQRAISEPVFAFYLSKDEREGSVVMFGGVDHRYYEGELNWVPLIQAGDWSVHMDRISIERKIIACSDGCKALVDTGTSDIVGPRRLVNNIHRLIGAIPRGSEHYVPCSEVNTLPSIVFTINGINYPVPGRAYILKDDRGRCYTTFQENRVSSSTETWYLGDVFLRLYFSVFDRGNDRIGLARAVGGGGSHHHHHHHHHH |
| Expression System | HEK293 |
| Molecular Weight | Theoretical:17.6kDa Actual:20-30kDa |
| Purity | ＞95% by SDS-PAGE |
| Endotoxin | <1EU/μg |
| Tag | His Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, 1mM EDTA, pH7.4. |
| Reconstitution | Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation. |
| Stability & Storage | 12 months from date of receipt, -20 to -70 °C as supplied. 6 months, -20 to -70 °C under sterile conditions after reconstitution. 1 week, 2 to 8 °C under sterile conditions after reconstitution. Please avoid repeated freeze-thaw cycles. |
Background
Desmoglein-3 is a protein that in humans is encoded by the DSG3 gene. In the skin epidermis Desmoglein-3 is expressed in the basal lower layers of the epidermis, and dominates in terms of expression on mucosal surfaces compared to Desmoglein-1. Desmoglein-3, along with Desmoglein-1, has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus vulgaris. The mucosal dominant form of pemphigus vulgaris only involves antibodies against Desmoglein-3 and causes mucosal erosions, but no skin lesions. Desmoglein-3 serves as a prognostic marker of Esophageal Squamous Cell Carcinoma (ESCC), and may even be involved in the progression of ESCC.
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4.7 ★★★★★
Based on 20 reviews
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Product Reviews
★★★★★ 5
Excellent Product, thanks!
Size: 10FT, Color: Black-20W
Excellent Product, thanks!
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Reviewed in the United States on May 3, 2026
★★★★★ 5
Great
Size: 6FT, Color: Black-20W
I used these in custom built nightstands, and customers loved them.
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Reviewed in the United States on May 4, 2026
★★★★★ 5
Does what I needed it to do
Size: 50mm/2inch, Color: Black, Number of Items: 4
Worked perfectly for routing all my wires for my desk. The included tie straps were an added bonus. Now everything is nice, tidy and secured to the back side of my rolling desk.
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Reviewed in the United States on May 6, 2026
★★★★★ 5
Great value
Size: 50mm/2inch, Color: Black, Number of Items: 2
Great price. Worked perfectly.
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Reviewed in the United States on May 1, 2026
★★★★★ 5
Great to clean up the cable clutter
Size: 50mm/2inch, Color: Black, Number of Items: 4
I finally got around to cleaning up the cable disaster on my home office desk and these grommets were exactly what I needed. They fit perfectly into the 2-inch holes I drilled, and the plastic feels surprisingly sturdy, not like that cheap, brittle stuff that snaps the moment you try to pop the cover back on. The little brush-like opening is a nice touch because it keeps the cords from sliding back down when they aren't plugged in, and the black finish looks really clean against my wood tabletop. For a 4-pack, the price was a total steal, and it honestly makes the whole setup look way more professional than just having raw holes in the desk. If humans are looking for a quick and cheap way to hide cord clutter, these are a solid bet.
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Reviewed in the United States on February 10, 2026