SKU: 59863304929

Mouse Anti-Human TCR α/β Antibody (S-R686)

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Description

Mouse Anti-Human TCR α/β Antibody (S-R686)Product Specification Host Mouse Antigen TCR Synonyms TCR; TCR Location Cell membrane Accession P01848 P01850 Clone Number S R686 Antibody Type Mouse mAb Application FCM Reactivity Hu Positive Sample Human PBMC Concentration 2 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS pH7. 4 Stability & Storage 12 months from date of receipt reconstitution, 2 to 8 C as supplied. Dilution application dilution species FCM 1: 200 Hu

Product Specification


Host Mouse
Antigen TCR α/β
Synonyms α/β TCR; TCR α/β
Location Cell membrane
Accession P01848、 P01850
Clone Number S-R686
Antibody Type Mouse mAb
Application FCM
Reactivity Hu
Positive Sample Human PBMC
Concentration 2 mg/ml
Conjugation Unconjugated
Physical Appearance Liquid
Storage Buffer

PBS pH7.4

Stability & Storage 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied.

Dilution


application dilution species
FCM 1:200 Hu

Background

The T cell receptor (TCR) α and β proteins are essential components of the αβ T cell receptor, a heterodimeric surface protein expressed on T lymphocytes that recognizes antigenic peptides presented by major histocompatibility complex (MHC) molecules. The TCR α chain is encoded by the TRAC (T cell receptor alpha constant) and TRAV (T cell receptor alpha variable) genes, while the TCR β chain is encoded by the TRBC (T cell receptor beta constant) and TRBV (T cell receptor beta variable) genes, along with diversity (TRBD) and joining (TRBJ) segments, enabling extensive combinatorial diversity. Structurally, both chains consist of a variable (V) domain responsible for antigen recognition and a constant (C) domain that anchors the receptor to the cell membrane. The TCR αβ heterodimer associates with the CD3 complex (CD3γε, CD3δε, and CD247 ζζ) to form a functional TCR-CD3 signaling unit, which transmits activation signals upon peptide-MHC engagement. TCR β undergoes V(D)J recombination during thymic development, contributing to the receptor's antigen specificity, whereas TCR α lacks a D segment but still undergoes recombination for diversity. Mutations or dysregulation in TCR α/β genes can lead to immune disorders, including T cell malignancies and autoimmune diseases. TCR αβ T cells are critical for adaptive immunity, mediating responses against infections, tumors, and self-antigens in autoimmune conditions.

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SKU: 59863304929

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Mchu
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★★★★★ 5
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I bought this for my friend since she has really been into sewing and dressing up in bolder outfit. When she saw the book, she told me she has been eyeing this and was really interested in the different color combinations. It is a small but unique book with so many different patterns and color combinations that can inspire people's lives with how they dress or decorate their living area.
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Reviewed in the United States on February 12, 2026
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C. Rojas
New York, US
★★★★★ 5
Get It!
Format: Paperback
Fast shipping and great product! Perfect for fashion designers
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Reviewed in the United States on August 18, 2025
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Caroline
Houston, US
★★★★★ 5
Lightweight, Gentle & perfect for sensitive skin, instant hydration
Size: 3 Fl Oz (Pack of 1), Size: 3 Fl Oz (Pack of 1)
I received this CeraVe PM Facial Moisturizing Lotion this morning and tried it for the first time tonight, and I’m already really impressed. The texture is lightweight and smooth. It applies easily and absorbs quickly without leaving any greasy or sticky feeling. My skin felt instantly hydrated, soft, and comfortable. What I like most is how gentle it is. I’m currently using treatments that make my skin more sensitive, and this moisturizer didn’t cause any irritation at all. It actually helped calm my skin and made it feel more balanced. I also appreciate that it contains ingredients like niacinamide, ceramides, and hyaluronic acid, which are great for supporting the skin barrier and hydration. After just one use, my skin already looks more supple and healthy. It’s a great option for nighttime, especially if you don’t like heavy creams. So far, I’m very happy with it and will definitely keep using it.
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Reviewed in the United States on April 4, 2026
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Mohammad
Dallas, US
★★★★★ 5
Highly recommended for all skin types!
Size: 3 Fl Oz (Pack of 1)
Game-Changer Night Moisturizer – Lightweight, Hydrating & Perfect for Sensitive Skin I’ve been using the CeraVe PM Facial Moisturizing Lotion for a few weeks now, and honestly, it has become a staple in my skincare routine. First thing I noticed is how lightweight and fast-absorbing it is. It sinks into the skin within seconds without leaving any greasy or sticky feeling, which is perfect if you don’t like heavy night creams. Despite being lightweight, it provides deep hydration throughout the night—I wake up with soft, smooth, and refreshed skin. What really makes this product stand out is its ingredient combination: • Hyaluronic acid keeps my skin hydrated by locking in moisture • Niacinamide helps calm my skin and reduces redness • Ceramides (1, 3, 6-II) strengthen the skin barrier I also love that it’s fragrance-free, oil-free, and non-comedogenic, so it doesn’t clog pores or irritate my skin. I have slightly sensitive and acne-prone skin, and this has worked perfectly without causing breakouts.
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Reviewed in the United States on April 9, 2026
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Mil
Lake Worth, US
★★★★★ 5
Soft, Gentle, and Perfect for Nighttime Hydration!
Size: 3 Fl Oz (Pack of 1), Size: 3 Fl Oz (Pack of 1)
I absolutely love this moisturizer! The texture is super soft, lightweight, and feels amazing on my skin. It hydrates really well without feeling greasy or heavy, and my face feels smooth and refreshed every time I use it. I also love that it’s gentle and doesn’t irritate my skin at all. Perfect for nighttime and my skin looks healthier in the morning. Definitely one of my favorite skincare products!
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Reviewed in the United States on May 7, 2026

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