SKU: 63961105553

SFXN1/TCC Rabbit Polyclonal Antibody

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Description

SFXN1/TCC Rabbit Polyclonal AntibodyProduct Specification Host Rabbit Antigen SFXN1 TCC Synonyms Sideroflexin 1; Sfxn1 Immunogen Recombinant Protein Location Mitochondrion Accession Q99JR1 Antibody Type Polyclonal antibody Isotype IgG Application WB, IHC P Reactivity Hu, Ms, Rt, Mk Positive Sample PC 3, LNCaP, MCF7, HepG2, NIH 3T3, mouse brain, C6, rat brain, COS 7 Purification Immunogen Affinity Concentration 0. 5 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer

Product Specification


Host Rabbit
Antigen SFXN1/TCC
Synonyms Sideroflexin-1; Sfxn1
Immunogen Recombinant Protein
Location Mitochondrion
Accession Q99JR1
Antibody Type Polyclonal antibody
Isotype IgG
Application WB, IHC-P
Reactivity Hu, Ms, Rt, Mk
Positive Sample PC-3, LNCaP, MCF7, HepG2, NIH/3T3, mouse brain, C6, rat brain, COS-7
Purification Immunogen Affinity
Concentration 0.5 mg/ml
Conjugation Unconjugated
Physical Appearance Liquid
Storage Buffer

PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300

Stability & Storage

12 months from date of receipt / reconstitution, -20 °C as supplied

Dilution


application dilution species
WB 1:1000 Hu, Ms, Rt, Mk
IHC-P 1:200 Hu, Ms, Rt

Background

SFXN1/TCC (sideroflexin-1/tricarboxylate carrier) is an ~35 kDa integral inner-mitochondrial-membrane protein that functions as a metabolite transporter, exporting mitochondrial acetyl-CoA to the cytosol for lipogenesis and importing serine (and possibly tricarboxylates or iron-related substrates) into the matrix to support one-carbon metabolism, heme/iron–sulfur biogenesis and redox balance, with mutations causing flexed-tail anemia and mitochondrial iron overload in mice and implicating the carrier in human metabolic and neurodegenerative disorders.

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SKU: 63961105553

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4.1 ★★★★★
Based on 23 reviews
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zee
Waukegan, US
★★★★★ 5
Great toys for aggressive chewers
Size: Medium/Large, Color: Turkey Day Drumstick - Large
These are great toys they last a while they are destroyed after a while but both dogs are aggressive chewers but they last about a year and a half. And they are go to toys they have one that is a shark mouth and they love it I have bought 4. (two of them the pups lost ).
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Reviewed in the United States on December 20, 2025
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Verified Purchase
Anjelica
Alexandria, US
★★★★★ 4
Durable and Fun, Just Gets a Bit Rough
Size: Medium/Large, Color: Chopper - Large
This is a really good toy overall, especially if you have dogs that love to chew. My dogs were immediately into it—they play with it nonstop, toss it around, and stay entertained for a while, which I love. It definitely holds up better than most toys we’ve tried. The only reason I’m giving it 4 stars instead of 5 is because over time it does start to fray a bit and gets a little rough, especially with heavy chewing. It’s not completely indestructible, but it still lasts longer than a lot of other toys. Overall, still a great buy and I would recommend it if your dogs need something tough but fun!
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Reviewed in the United States on April 4, 2026
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Lina
New York, US
★★★★★ 5
Worthwhile!
Size: Medium/Large, Color: Turkey Day Drumstick - Large
I have a small dog with a really strong bite! Usually have to buy toys that are meant for bigger dogs. This has lasted us for what feels like forever. It does sound very heavy when dropped! My dog loves it though! Would definitely recommend!
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Reviewed in the United States on May 2, 2026
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Verified Purchase
Kelly
Massapequa, US
★★★★★ 5
Ohhh Mr. Iguana
Size: Medium/Large, Color: Illana the Iguana - Large
Mr. Iguana is a house favorite! I got my first one of these in a barkbox and my dog loved it so much, i went on the hunt for another one. Amazon saved the day! I own about 7 of these now. They are prefect for dogs just love to chew, they hold up great! And they are heavy duty, super easy to clean! My dogs are very happy, great value for the money! Doesn't have a smell, vibrant colors! Noise level is quiet, minus my dogs chewing !
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Reviewed in the United States on August 13, 2025
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Verified Purchase
sec682
Phoenix, US
★★★★★ 3
Not for strong chewers
Size: Medium/Large, Color: Dog Ness Monster - Large
Initially, I really liked this for my dog. She is about 8 months old and still loves to chew and destroys most toys in a few minutes. When we got this, it seemed like it would hold up for a while despite being clearly gnawed on. Unfortunately, once she focused on the softer "water" portion of the toy, that is where things went downhill with this toy. After a few short chew sessions, she was tearing chunks out of it. We had purchased a replacement since she liked the original so much, and after about 5 minutes with the replacement, she had taken enough out of the blue section that we immediately threw that one out as well. Overall while the green portion held up, the blue didn't. I can't recommend this for strong chewers.
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Reviewed in the United States on December 8, 2025

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