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Description
Pacific Blue Armenian hamster Anti-Mouse/Rat/Human CD27 Antibody (S-R620)Product Specification Host Armenian hamster Antigen CD27 Synonyms CD27 antigen; CD27L receptor; T cell activation antigen CD27; T14; Tumor necrosis factor receptor superfamily member 7Imported; TNFRSF7 Location Cell membrane Accession P26842P41272Q501W2 Clone Number S R620 Antibody Type Recombinant mAb Isotype IgG Application FCM Reactivity Hu, Ms, Rt Positive Sample Human PBMC Purification Protein G Concentration 0. 2 mg ml Conjugation Pacific Blue
Product Specification
| Host | Armenian hamster |
| Antigen | CD27 |
| Synonyms | CD27 antigen; CD27L receptor; T-cell activation antigen CD27; T14; Tumor necrosis factor receptor superfamily member 7Imported; TNFRSF7 |
| Location | Cell membrane |
| Accession | P26842、P41272、Q501W2 |
| Clone Number | S-R620 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | FCM |
| Reactivity | Hu, Ms, Rt |
| Positive Sample | Human PBMC |
| Purification | Protein G |
| Concentration | 0.2 mg/ml |
| Conjugation | Pacific Blue |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 1% BSA, 0.3% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied |
Dilution
| application | dilution | species |
| FCM | 1.25μl per million cells in 100μl volume | Hu |
Background
CD27 protein is a member of the tumor necrosis factor (TNF) receptor superfamily. It is expressed on the surface of various immune cells such as T cells and B cells. CD27 can interact with its ligand CD70, which is mainly found on antigen - presenting cells (APCs) and activated T cells. This interaction plays a crucial role in the regulation of immune responses. It can promote T cell proliferation and differentiation, enhance the cytotoxic activity of T cells against infected or cancerous cells, and also participate in the regulation of B cell functions such as immunoglobulin production. Moreover, the CD27 - CD70 pathway is involved in the development and maintenance of immune memory, helping the immune system to remember and respond more effectively to pathogens it has previously encountered. Abnormal expression or function of CD27 has been implicated in certain immune - related diseases and cancers, making it a potential target for therapeutic interventions in these conditions.
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4.0 ★★★★★
Based on 10 reviews
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Product Reviews
★★★★★ 5
LOVED IT!
LOVED IT!
I’ve been using the Simple brand makeup wipes removers and they’re THE BEST I have tried especially since I have extremely sensitive skin. Even though this moisturizer is a bit(but just a tiny bit) greasy, I don’t mind because it’s REALLY moisturizing and it’s perfect for my combination skin. It’s a gel but it’s a bit watery. However, once you put some on your face your skin just drinks it in. You don’t need much of the product because just a small amount of product is needed. My face feels nice afterwards and soft. Bought 2 more for back ups. Also, yes it’s a small tube(which it’s perfect for traveling) but honestly a little bit goes a long way because you don’t need too much product since it’s a watery gel so I think the tube can last quite a bit! I love this brand and will look into trying some of their other products in the near future.
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Reviewed in the United States on April 30, 2020
★★★★★ 3
Does the job for less $
I bought this moisturizer when a move to California left my face looking its age for the first time in my life. The Arnica-infused Olive Oil I've been using for years was protecting my skin as a barrier, but not adding any hydration, and the drier climate forced a change. I was looking for something without synthetic fragrance, heavy oils, or a high price tag. Simple's Hydrating Gel Cream fit the bill, and I was curious about how a gel might feel. After a week of use I have noticed a few small spots which don't stay long, but my décolletage did produce some worrying pimples. I'm not ready to throw it out yet, because there are other factors to eliminate before passing judgement. My face is perceptively brighter and the skin under my eyes (main problem area) is improving. A little goes a long ways - so no need to fret over a mere 1.7oz. The gel does take a few moments to absorb, and I generally give it a few more minutes to sink in before I am able to apply a mineral sunscreen in the morning without "pilling." Also, I get a subtlely warm sensation on my face after having exfoliated - but there is no accompanying redness or lasting irritation - probably some of the fillers having a mild reaction on the surface. So far I'm willing to continue using this product because I think it's a good value for the price. Not sure I'd stick with it if I found something better though.
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Reviewed in the United States on February 18, 2020
★★★★★ 5
The best product i have EVER used!!!!!!
This is honestly the best product i have EVER used. I’ve been using it for 2-3 years. I have super sensitive skin and for some reason my skin gets SUPER dehydrated. I have tried many products but nothing has worked as well as this. I swear by this hydrating moisturizer/gel and i recommend it to any and everyone. I do the upwards and outward motions like suggested and it instantly absorbs. It never feels sticky which is a HUGE plus. A little bit definitely goes a long way. I use it on my face, neck and other areas of my body that seems to feel dehydrated (elbows, knees and back of hands). I have heard from multiple people that my face has never looked more hydrated than it does right now. My favorite part is every time i apply it it always feel cool temperature wise. It leaves a cool and clean feeling like i have put a cool compress on my face. I would recommend this product 100x over and over.
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Reviewed in the United States on April 6, 2021
★★★★★ 5
Best cream ever!
I really love this “Simple” gel cream I hope they never stop making it. I have oily skin and other creams seem to just Irritate my skin or just feel thick and heavy like it’s blocking my pores. Not this cream. It feels light weight and yet moisturizing. It has no scent. I use it all over my face and my neck. I have bought department store moisturizers and yet I keep coming back to this Simple hydrating gel cream it never fails me. The only problem is I discovered I can’t find it in any of the stores anymore in my area, I don’t know why but I never thought to look for it here on Amazon. So now I’m a faithful purchaser of this product here on Amazon I love it so much I just hope the company still will continue to make it and that Amazon will continue to sell it.
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Reviewed in the United States on May 6, 2021
★★★★★ 5
Is this the CURE!
Size: Regular, Color: Cream
I have a skin disease called Ichthyosis Vulgaris. Yes, SCALEY FISH! Thanks MOM! This unfortunate crud leaves my heels an embarrassing mess! They are cracked and dry and literally like concrete. I have had this disease all my life and there is NO cure. It's hideous! Anyway, I have tried so many different experiments to help improve my situation. So much time and money I will never get back. So when I saw these, I had to give them a try too because I am a forever optimist and love being disappointed. Here's how it went.
First I put my dermatologist recommended AmLactin on my crusty heels. Then, I put the socks on. By the way, with no problem at all, and went to bed. I was not too hot, which is usually what happens when I sleep with socks on. I never even realized that I had them on. When I woke up, I took them off and immediately used a "Heel File" over a towel removing all the yuck!. Then, I sand papered them to smooth the skin out. Then, I doused them with Shea and Aloe foot lotion I found at the bottom of my experiment drawer in my bathroom. Oh, they felt like someone else's feet. I am very hopeful at this moment! Is this the cure to my embarrassing situation? I sure hope so. Spring is here and I would really like to wear my cute flip-flops when I go to the Waffle House and set at the bar. Wasn't that a picture on Facebook of someone nasty heels? It made me gag. Then, I had to make sure that picture wasn't me! I am going to do this for a week and come back for another review. Wish me luck ya'll!
UPDATE!
So it’s been about two weeks. I wish that I had taken a before and after picture. I guess I figure that this too will be a waste of money. NO! These little socks are a God send for me. I did buy AmLactin foot repair cream and that I highly recommend. It’s the best so far. They also offer an option with heel socks. They are soft and work very well also but one negative. They leave fuzzies on you feet and tools. Guys this is it for me. My search is over! I went to my mani/pedi queen yesterday and she was shocked when she saw my feet. She is spreading the word!
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Reviewed in the United States on March 23, 2025