SKU: 69230515214

IL-3 Rα/CD123 Fc Chimera Protein, Human

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Description

IL-3 Rα/CD123 Fc Chimera Protein, HumanProduct Specification Species Human Accession P26951 1 Amino Acid Sequence Thr19 Arg305, with C terminal Human hIgG1 Fc

Product Specification


Species Human
Accession P26951-1
Amino Acid Sequence

Thr19-Arg305, with C-terminal Human hIgG1 Fc TKEDPNPPITNLRMKAKAQQLTWDLNRNVTDIECVKDADYSMPAVNNSYCQFGAISLCEVTNYTVRVANPPFSTWILFPENSGKPWAGAENLTCWIHDVDFLSCSWAVGPGAPADVQYDLYLNVANRRQQYECLHYKTDAQGTRIGCRFDDISRLSSGSQSSHILVRGRSAAFGIPCTDKFVVFSQIEILTPPNMTAKCNKTHSFMHWKMRSHFNRKFRYELQIQKRMQPVITEQVRDRTSFQLLNPGTYTVQIRARERVYEFLSAWSTPQRFECDQEEGANTRAWRIEGRMDPKSSDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK

Expression System HEK293
Molecular Weight

72-95kDa (Reducing)

Purity

>95% by SDS-PAGE

Endotoxin <0.1EU/μg
Conjugation Unconjugated
Tag Human Fc Tag
Physical Appearance Lyophilized Powder
Storage Buffer

PBS, pH7.4

Reconstitution

Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.

Stability & Storage

· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.

· 3 months, -20 to -80℃ under sterile conditions after reconstitution.

· 1 week, 2 to 8℃ under sterile conditions after reconstitution.

· Please avoid repeated freeze-thaw cycles.

Background

Human IL-3 Rα is expressed from human 293 cells. It contains AA Thr19 - Arg305. This protein carries a polyhistidine tag at the C-terminus. Interleukin 3 receptor alpha (low affinity) (IL3RA), also known as CD123 (Cluster of Differentiation 123) is a 45-62kDa glycoprotein member of the hematopoietin receptor superfamily. This protein associates with a beta subunit common to the receptors for IL-5 and granulocyte-macrophage colony-stimulating factor (GM-CSF) to form a high-affinity receptor for IL-3. The interleukin-3 receptor α chain (CD123) has been identified as a potential immunotherapeutic target because it is overexpressed in AML compared with normal hematopoietic stem cells.

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Exchange/Return Notes
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SKU: 69230515214

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JoahJ
Bozeman, US
★★★★★ 5
It's exceptionally NICE!! BUY this one.
Color: Square Tissue Box-retro
Sturdy, solid construction. The magnetic closure works great. The interior of the holder is expertly crafted and finished. The exterior is Beautiful! It looks absolutely elegant. I am impressed! This facial tissue box cover exceeds my expectations and it is an exceptional value. Do not hesitate to purchase this marvelous cover.
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Reviewed in the United States on March 25, 2026
G
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GSB
Battle Creek, US
★★★★★ 5
Sturdy and good fit.
Color: Multifunctional Tissue Box-retro
Well made and perfect for the drop down table in between our two recliners in our couch. Holds all four of our remotes. Tissues come out easily and are easy to put into the holder as well. Looks very fancy. Great value for the money.
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Reviewed in the United States on July 15, 2025
D
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Deb G
Cuba, US
★★★★★ 5
Works great
Color: Square Tissue Box-retro
I bought this to prevent our puppy from chewing up the Kleenex boxes. Worked like a charm and looks good too. Not flimsy, nice quality.
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Reviewed in the United States on April 2, 2026
M
Verified Purchase
Mrs. Hawkins
Grantham, US
★★★★★ 5
Beautiful and well made
Color: Rectangular Tissue Box-retro
Such a beautiful and well made kleenex box. I absolutely love mine. I ordered 2 more after receiving my 1st one for my office. Easy to get the box in. Looks so nice and the kleenex feeds out of it easily. I even ordered my parents one for their office as a gift.
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Reviewed in the United States on March 11, 2026
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KY-Barbara
San Leandro, US
★★★★★ 5
Very Pretty and Nice Addition to my Living Room
Color: Square Tissue Box-retro
These look nice and were reasonably priced. Putting my tissue boxes in these holders also stopped my dog from tearing up boxes of tissues (he likes to tear up paper). he has not bothers these. They help the tissues blend into the decor without the distractions of the funky colors on the cardboard boxes.
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Reviewed in the United States on March 6, 2026

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