SKU: 69421425830

FGF-6 Protein, Human

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Description

FGF-6 Protein, HumanProduct Specification Species Human Synonyms Fibroblast growth factor 6, FGF 6, Heparin secretory transforming protein 2 (HST 2; HSTF 2), Heparin binding growth factor 6 (HBGF 6) Accession P10767 Amino Acid Sequence Gly41 Ile208 Expression System E. coli Molecular Weight 14 15 kDa (Reducing) Purity >95% by SDS PAGE, >90% by HPLC. Endotoxin <0. 1EU g Conjugation Unconjugated Tag No Tag Physical Appearance Lyophilized powder Storage Buffer PBS, pH7. 4

Product Specification


Species Human
Synonyms Fibroblast growth factor 6, FGF-6, Heparin secretory-transforming protein 2 (HST-2; HSTF-2), Heparin-binding growth factor 6 (HBGF-6)
Accession P10767
Amino Acid Sequence

Gly41-Ile208

Expression System E.coli
Molecular Weight

14-15 kDa (Reducing)

Purity >95% by SDS-PAGE, >90% by HPLC.
Endotoxin <0.1EU/μg
Conjugation Unconjugated
Tag No Tag
Physical Appearance Lyophilized powder
Storage Buffer

PBS, pH7.4

Reconstitution

Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.

Stability & Storage

·12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
·3 months, -20 to -80℃ under sterile conditions after reconstitution.
·1 week, 2 to 8℃ under sterile conditions after reconstitution.
·Please avoid repeated freeze-thaw cycles.

Reference

Genes & Dev. 1997;11(16):2040-2051.
Nat Commun. 2020;11(1):1421.

Background

Fibroblast growth factor 6 (FGF-6), also designated as HST2 or HBGF-6, is a secreted peptide growth factor belonging to the paracrine FGF subfamily. The FGF6 gene, located on human chromosome 12p13, encodes an 18.9 kDa protein that exhibits the highest expression in skeletal muscle and myogenic progenitor cells throughout embryonic development and adulthood. FGF-6 binds preferentially to fibroblast growth factor receptor 4 (FGFR4) with heparan sulfate proteoglycan co-receptor dependency, triggering downstream signaling through the MAPK/ERK1/2 and PI3K/AKT pathways.Functionally, FGF-6 operates as a dose-dependent regulator of myogenesis, promoting satellite cell proliferation at high concentrations and initiating myogenic differentiation via calcineurin-dependent pathways at lower concentrations. Beyond muscle physiology, FGF-6 exhibits pleiotropic functions in bone remodeling, iron homeostasis, thermogenesis, and oncogenesis, harboring both regenerative and tumorigenic activities.
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SKU: 69421425830

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ReadingWriteNow
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★★★★★ 5
They work very well.
Number of Items: 2
I love these. I use them to wrap my tumbler before sublimating them in my sublimation oven. They work every well to let me see the process so I don’t scorch my design.
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Reviewed in the United States on October 16, 2025
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Christina M Webb
Omaha, US
★★★★★ 5
PERFECT HEAT TAPE
Number of Items: 6
Love this heat tape - it's clear so no worry about color transferring to products from heat transfer, very functional for these uses. I have ordered this several times and this is my product of choice for my sublimation needs. Sticks well to product, no residue left on products, easy to use, easy to remove after use, very durable for sublimation use.
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Reviewed in the United States on May 28, 2025
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Beth Seward
Louisville, US
★★★★★ 5
Works very well
Number of Items: 4
As described, I love that is clear
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Reviewed in the United States on March 10, 2026
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Bea Rosey
Port Orchard, US
★★★★★ 5
Great tape for sublimation!
Number of Items: 4
Love love this tape. I used amber colored tape in the past and the color would transfer onto what I was making. This sticks well, is wide so it adds extra durability, and does not transfer color! If you’re just starting your sublimation journey, I highly recommend using this tape!
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Reviewed in the United States on February 11, 2026
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Amanda
Carnegie, US
★★★★★ 5
Good quality
Number of Items: 4
Great tape for using with a heat press. It doesn’t leave any marks and comes up easy. I use it for taping down sublimation stuff and have had no issues on slate, shirts, metal or anything I’ve made it sticks well and comes off easy.
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Reviewed in the United States on July 20, 2025

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