SKU: 70890304464

EphA5 His Tag Protein, Human

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Description

EphA5 His Tag Protein, HumanProduct Specification Species Human Synonyms EHK 1, EK7, BSK, EHK1, HEK7, TYRO4, Rek7, TYRO4HEK7CEK7 Accession P54756 Amino Acid Sequence Pro25 Pro573, with C terminal 10*His

Product Specification


Species Human
Synonyms EHK-1, EK7, BSK, EHK1, HEK7, TYRO4, Rek7, TYRO4HEK7CEK7
Accession P54756
Amino Acid Sequence

Pro25-Pro573, with C-terminal 10*His PASLAGCYSAPRRAPLWTCLLLCAALRTLLASPSNEVNLLDSRTVMGDLGWIAFPKNGWEEIGEVDENYAPIHTYQVCKVMEQNQNNWLLTSWISNEGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESDDQNGRNIKENQYIKIDTIAADESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGACIALVSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCVNHSVTDEPPKMHCSAEGEWLVPIGKCMCKAGYEEKNGTCQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVCEKDYFRRESDPPTMACTRPPSAPRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKCNSHAGVCEECGGHVRYLPRQSGLKNTSVMMVDLLAHTNYTFEIEAVNGVSDLSPGARQYVSVNVTTNQAAPSPVTNVKKGKIAKNSISLSWQEPDRPNGIILEYEIKYFEKDQETSYTIIKSKETTITAEGLKPASVYVFQIRARTAAGYGVFSRRFEFETTPVFAASSDQSQIPGGGSGGGSHHHHHHHHHH

Expression System HEK293
Molecular Weight 72-85kDa
Purity >95% by SDS-PAGE
Endotoxin <0.1EU/μg
Conjugation Unconjugated
Tag His Tag
Physical Appearance Lyophilized Powder
Storage Buffer PBS, pH7.4
Reconstitution Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability & Storage · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.
Reference

1. CHENGYING LIU, YAN HE, XIAO FENG, et al. Expression of EPHA5 in lung adenocarcinoma is associated with lymph node metastasis and EGFR mutation[J]. 2022,130(6):338-345.

Background

EPHA5 is a member of the Eph family of tyrosine kinase receptors, which affect carcinogenesis. High expression of EPHA5 was found in NCI‐H460 and H1299 cells, while low expression was observed in A549 and SPC‐A1 cells. EPHA5 was knocked down in NCI‐H460 and H1299 lung cancer cell lines using siRNAs. EPHA5 receptor is differently expressed in lung adenocarcinoma tissues, in which positive and negative expression of EPHA5 was found in 58.1% and 41.9% of tissues, respectively.EPHA5 receptor plays a role in tumor promotion in lung adenocarcinoma and it is a potential target for lung adenocarcinoma treatment.

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SKU: 70890304464

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J. Christian
Belleville, US
★★★★★ 4
Interesting book
Format: Paperback
I am not a lawyer, nor a writer, but rather a reader. I found the correlation of legal storytelling with sceenplay, literary narrative quite interesting. Legal trials are theater.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on March 20, 2014
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Classics professor
Grantham, US
★★★★★ 5
Highly recommended -- not just for lawyers!
Format: Paperback
I'm not a lawyer but a Classics professor looking for modern parallels to (and contrasts with) Cicero's persuasive strategies in Roman courts. This book was just what I was looking for: lucid, informative, smart, and as a bonus, well versed in narrative theory, which Meyer handles as an experienced teacher -- avoiding jargon and needless complication, illustrating the key ideas with well-known cinematic examples.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on April 20, 2017
D
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Danley Wolfe
Pawtucket, US
★★★★★ 5
Super overview and commentary on the historiy and many iterations/amendments
Format: Hardcover
I purchased and carefully read Jeff Kosseff's "The Twenty-Six Words That Created the Internet." It is an illuminating and thorough account of all facets of the legislation including history, enactment, modifications and amendments etc. A complex subject to understand, Mr. Kosseff did an outstanding job of presenting the complicated history and details and understanding of why this is incredibly important leading up to the form that is now in use. Some reviewers complain about too much detail, but I disagree, it is very important to understand the detail. A difficult topic and a great job of presentation. I would like to have a time line e.g., something like a "herring bone" chart notating all of the critical stages of development up to the present ... from initial concepts to Section 230 rollout and the important changes / amendments in both substance and use of 230. I am now reading Koseff's latest book on a similar but different topic, "The United States of Anonymous" which deals with how the first amendment shaped the development of our online speech.
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Reviewed in the United States on March 16, 2023
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J. Lee
Lowell, US
★★★★★ 5
Entertaining, educational and provoking
Format: Hardcover
I really didn’t expect this level of enjoyment from reading a book about a serious law material. This book is entertaining almost like a thrilling mini series to me due to the author’s great storytelling. Vivid arguments in various courtrooms over decades, sad stories of victims, some hilarious cases (especially Smith), unjust and unfair cases, interesting judges, … I just enjoyed reading them over cover to cover. It is definitely educational. I don't have any legal background and I hardly knew Section 230. After the joyful reading, I could learn history, importance and main issues of Section 230. I believe it is a must-read to many people including software engineers like me. I couldn’t be comfortable when the author compared the amount of benefit of Section 230, which has promoted proliferation of US Internet business, to the amount of suffering of women, children, and unfairly defamed people. However, I believe the author, on purpose, provoked this discussion. Including his own sincere opinion, he introduced various discussions deeply in later chapters, which helped me to think a lot.
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Reviewed in the United States on February 12, 2021
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A M
Los Angeles, US
★★★★★ 4
Interesting and clear
Format: Kindle
The book reviews the history of the law that protects interactive websites from prosecution due to defamation. The discussion is interesting and straightforward, but there are too many unimportant details in some places.
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Reviewed in the United States on November 2, 2022

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