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Description
Human IFN-alpha1, His tagProduct Specification Species Human Synonyms IFN alpha 1 13; Interferon alpha D (LeIF D) Accession P01562 Amino Acid Sequence Protein sequence(P01562, Cys24 Glu189, with C 10*His) CDLPETHSLDNRRTLMLLAQMSRISPSSCLMDRHDFGFPQEEFDGNQFQKAPAISVLHELIQQIFNLFTTKDSSAAWDEDLLDKFCTELYQQLNDLEACVMQEERVGETPLMNADSILAVKKYFRRITLYLTEKKYSPCAWEVVRAEIMRSLSLSTNLQERLRRKEGGGGSHHHHHHHHHH Expression System HEK293 Molecular Weight Theoretical: 21kDa Actual: 20kDa Purity 95% by SDS
Product Specification
| Species | Human |
| Synonyms | IFN-alpha-1/13; Interferon alpha-D (LeIF D) |
| Accession | P01562 |
| Amino Acid Sequence | Protein sequence(P01562, Cys24-Glu189, with C-10*His) |
| Expression System | HEK293 |
| Molecular Weight | Theoretical: 21kDa Actual: 20kDa |
| Purity | ＞95% by SDS-PAGE |
| Endotoxin | <1EU/μg |
| Conjugation | Unconjugated |
| Tag | His Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, pH7.4. |
| Reconstitution | Reconstitute no more than 0.1 mg/mL according to the size in deionized water after rapid centrifugation. |
| Stability & Storage |
12 months from date of receipt, -20 ℃ to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. Please avoid repeated freeze-thaw cycles. |
Background
INF-α1 is a member of the type I interferon family that is produced in response to viral infection as a key part of the innate immune response with potent antiviral, antiproliferative and immunomodulatory properties. This cytokine, like other type I interferons, binds a plasma membrane receptor made of IFNAR1 and IFNAR2 that is ubiquitously expressed, and thus is able to act on virtually all body cells. This cytokine is upregulated in preeclamptic placentas and is thought to be a mediator of preeclampsia.
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