SKU: 75549573203

VDAC3 Rabbit Polyclonal Antibody

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Description

VDAC3 Rabbit Polyclonal AntibodyProduct Specification Host Rabbit Antigen VDAC3 Synonyms Non selective voltage gated ion channel VDAC3; VDAC 3; hVDAC3Alternative nameOuter mitochondrial membrane protein porin 3 Immunogen Synthetic Peptide Location Mitochondrion Accession Q9Y277 Antibody Type Polyclonal antibody Isotype IgG Application WB, IHC P Reactivity Hu, Ms, Rt Positive Sample HEK293, Jurkat, A431, MCF7, HeLa, HepG2, MEF, NIH 3T3, mouse brain, mouse heart, PC 12, rat brain, rat

Product Specification


Host Rabbit
Antigen VDAC3
Synonyms Non-selective voltage-gated ion channel VDAC3; VDAC-3; hVDAC3Alternative nameOuter mitochondrial membrane protein porin 3
Immunogen Synthetic Peptide
Location Mitochondrion
Accession Q9Y277
Antibody Type Polyclonal antibody
Isotype IgG
Application WB, IHC-P
Reactivity Hu, Ms, Rt
Positive Sample HEK293, Jurkat, A431, MCF7, HeLa, HepG2, MEF, NIH/3T3, mouse brain, mouse heart, PC-12, rat brain, rat heart
Predicted Reactivity BV, Pg, Rb, Or
Purification Immunogen Affinity
Concentration 2 mg/ml
Conjugation Unconjugated
Physical Appearance Liquid
Storage Buffer

PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300

Stability & Storage

12 months from date of receipt / reconstitution, -20 °C as supplied

Dilution


application dilution species
WB 1:1000-1:2000 Hu, Ms, Rt
IHC-P 1:500 Hu, Ms, Rt

Background

VDAC3 (Voltage-Dependent Anion Channel 3) is a crucial isoform of the mitochondrial outer membrane porin family that distinguishes itself from its counterparts, VDAC1 and VDAC2, through unique structural features including an additional cysteine residue which facilitates the formation of intermolecular disulfide bonds and potential oligomerization. Primarily localized in the mitochondria of diverse tissues with particularly high expression in the brain, testes, and skeletal muscle, VDAC3 plays a specialized role in regulating metabolite flux, such as ATP and ADP exchange, while critically contributing to the assembly and stability of the sperm flagellar axoneme, where its dysfunction is directly linked to male infertility due to impaired sperm motility. Beyond its metabolic gating function, VDAC3 is implicated in modulating reactive oxygen species (ROS) levels and interacting with cytoskeletal elements, suggesting a broader involvement in cellular signaling pathways related to oxidative stress response and apoptosis, although its precise gating mechanisms and specific protein-protein interaction networks remain less fully characterized compared to the more ubiquitous VDAC1.

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SKU: 75549573203

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★★★★★ 5
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Reviewed in the United States on August 22, 2025
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Chris K
Whiting, US
★★★★★ 3
Tall girls only
Size: Medium, Color: White
Short, petite girls this looks funny and hits weirdly around the waist. Need to be tall and thin to make this dress look good. 5'1, size 6.
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Reviewed in the United States on June 11, 2025
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BW
Birmingham, US
★★★★★ 5
So stinking cute
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i LOVE these sunglass. I found some at TJ Maxx for 12 bucks on sale because they were cracked. Tried them on and new I wanted to find them only. They are not too big for my face, but could be form some people. I wore them every day on vacation in Mexico, and the sunshine did not bother me.
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Reviewed in the United States on June 23, 2025
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meike buttner
Lowell, US
★★★★★ 5
beautiful frames for your face!
Style: Vc907 Back Frame 100% Uv Protective Women's Cat Eye Sunglasses. Luxe Gifts for Her, 64.5 Mm, Color: Nude
i had bought these prior in dilards, but in a darker color. i fell in love with them and when they got scratched up i got so sad. i accidentally stumbled upon them here in this lighter color and OMG they’re so much nicer in this color! you don’t nearly see the scratches as much or if even. and it looks so much nicer with all of the colors i wear. it fits the face so beautifully. gorgeous!
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Reviewed in the United States on July 13, 2024
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Grace Magana
Lake Worth, US
★★★★★ 5
Love ❤️ it!
Style: Vc907 Back Frame 100% Uv Protective Women's Cat Eye Sunglasses. Luxe Gifts for Her, 64.5 Mm, Color: Clear
Love them!
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Reviewed in the United States on April 8, 2026

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