SKU: 79863547982

Human LCK, His tag

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Description

Human LCK, His tagProduct Specification Species Human Accession P06239 Amino Acid Sequence Protein sequence(P06239, Asn64 Thr226, with C 10*His) NLVIALHSYEPSHDGDLGFEKGEQLRILEQSGEWWKAQSLTTGQEGFIPFNFVAKANSLEPEPWFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLSVRDFDQNQGEVVKHYKIRNLDNGGFYISPRITFPGLHELVRHYTNASDGLCTRLSRPCQTGGGGSHHHHHHHHHH Expression System HEK293 Molecular Weight Theoretical: 20. 1kDa Actual: 24 30kDa Purity >90% by SDS PAGE Endotoxin <1EU g Conjugation Unconjugated

Product Specification


Species Human
Accession P06239
Amino Acid Sequence

Protein sequence(P06239, Asn64-Thr226, with C-10*His)
NLVIALHSYEPSHDGDLGFEKGEQLRILEQSGEWWKAQSLTTGQEGFIPFNFVAKANSLEPEPWFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLSVRDFDQNQGEVVKHYKIRNLDNGGFYISPRITFPGLHELVRHYTNASDGLCTRLSRPCQTGGGGSHHHHHHHHHH

Expression System HEK293
Molecular Weight Theoretical: 20.1kDa Actual: 24-30kDa
Purity

>90% by SDS-PAGE

Endotoxin <1EU/μg
Conjugation Unconjugated
Tag His Tag
Physical Appearance Lyophilized Powder
Storage Buffer Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, pH7.4.
Reconstitution Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation.
Stability & Storage
  • 12 months from date of receipt, -20 ℃ to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.  
  • Please avoid repeated freeze-thaw cycles. 

Background

Lymphocyte-specific protein tyrosine kinase (LCK) is a member of the Src family of protein tyrosine kinases (PTKs). It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. LCK has emerged as one of the key molecules regulating T-cell functions. Studies using LCK knock-out mice or LCK-deficient T-cell lines have shown that LCK regulates the initiation of TCR signaling, T-cell development, and T-cell homeostasis. Because of the crucial role of LCK in T-cell responses, strategies have been employed to redirect LCK activity to improve the efficacy of chimeric antigen receptors (CARs) and to potentiate T-cell responses in cancer immunotherapy. In addition to the well-studied role of LCK in T cells, evidence has been accumulated suggesting that LCK is also expressed in the brain and in tumor cells, where it actively takes part in signaling processes regulating cellular functions like proliferation, survival and memory. Therefore, LCK has emerged as a novel druggable target molecule for the treatment of cancer and neuronal diseases. 

Shipping Notes
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Exchange/Return Notes
  • We offer a 30-day return/exchange service after receiving.
  • Final sale items are not eligible for returns or exchanges.
  • To process your return/exchange, please contact us at [email protected]
  • Please click here for more details>>> Return & Exchange Policy
SKU: 79863547982

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4.1 ★★★★★
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WW
Battle Creek, US
★★★★★ 5
Very useful
Color: Black
I’ve been using this room divider to separate my space from my daughter’s, and it has worked out really well. It provides just the right amount of privacy while still keeping the room feeling open and comfortable. The design is simple yet stylish, so it blends nicely with our decor. It’s also lightweight and easy to move when needed, which is a big plus. The material feels durable and well-made, not flimsy at all. Overall, it’s a practical and attractive solution for shared spaces, and I’m very happy with this purchase. I would definitely recommend it to others.
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Reviewed in the United States on April 16, 2026
A
Verified Purchase
Amy
Waukegan, US
★★★★★ 5
Great Room Divider
Color: Black
This product is a great room divider that decent quality and worth the price tag. The look is sleek and fits seamlessly into any room without complaint. The assembly was easy to follow and the quality is long lasting. Not only that, I need it as my sons share a room and we’re looking for some privacy. The divider is able to extend across a decently large area really divide the room as it has 4 panels. Overall, this is a great product for its cost and if your looking for a room divider that’s not too costly, this is the pick.
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Reviewed in the United States on April 12, 2026
A
Verified Purchase
AmazonUser333
Whiting, US
★★★★★ 5
Great for creating a workspace
Color: Grey
I needed a room divider that could be easily folded for storing to put behind my chair during my work calls. This works perfectly! Was very easy to put together. Lightweight but sturdy enough that it won’t fall over.
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Reviewed in the United States on February 27, 2026
I
Verified Purchase
Isa Rincon
Massapequa, US
★★★★★ 2
Base part of it
Color: Black
Even though I kept this it’s very uncomfortable because of the way the base works . They are very long at the bottom and it’s hard to open and close
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Reviewed in the United States on March 15, 2026
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Verified Purchase
MARIAH DANN
Los Angeles, US
★★★★★ 5
Great room separator
Color: Black
The panels are much longer than we expected! We only needed 3 of the 4 proivided. It's slightly flimsy, but holds together nicely. The screwdriver that came with did not fit the screws, but luckily we had a Phillips head. It's very lightweight. It is definitely a good value for the money.
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Reviewed in the United States on February 10, 2026

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