SKU: 82269752388

M-CSFR His Tag Protein, Cynomolgus

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Description

M-CSFR His Tag Protein, CynomolgusProduct Specification Species Cynomolgus Synonyms M CSFR, CD115, FIM2, FMS, CSF1R Accession G7P8P1 Amino Acid Sequence Ile99 Pro596, with C 8*His Expression System HEK293 Molecular Weight 80 95kDa Purity >95% by SDS PAGE Endotoxin <0. 1EU g Conjugation Unconjugated Tag His Tag Physical Appearance Lyophilized Powder Storage Buffer PBS, pH7. 4 Reconstitution Reconstitute at 0. 1 1 mg ml according to the size in ultrapure water after rapid

Product Specification


Species Cynomolgus
Synonyms M-CSFR, CD115, FIM2, FMS, CSF1R
Accession G7P8P1
Amino Acid Sequence Ile99-Pro596, with C-8*His
Expression System HEK293
Molecular Weight 80-95kDa
Purity >95% by SDS-PAGE
Endotoxin <0.1EU/μg
Conjugation Unconjugated
Tag His Tag
Physical Appearance Lyophilized Powder
Storage Buffer PBS, pH7.4
Reconstitution Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability & Storage 12 months from date of receipt, -20 to -70 °C as supplied; 6 months, -20 to -70 °C under sterile conditions after reconstitution; 1 week, 2 to 8 °C under sterile conditions after reconstitution; Please avoid repeated freeze-thaw cycles.
Reference

1、Sapi E. et al. (1999) The role of CSF-1 in normal and neoplastic breast physiology. Proc Soc Exp Biol Med. 220(1): 1-8.

2、Sapi E. (2004) The role of CSF-1 in normal physiology of mammary gland and breast cancer: an update. Exp Biol Med (Maywood). 229(1): 1-11.

3、Bonifer C. et al. (2008) The transcriptional regulation of the Colony-Stimulating Factor 1 Receptor (csf1r) gene during hematopoiesis. Front Biosci. 13: 549-560.

Background

Colony stimulating factor 1 receptor (CSF1R) is also known as macrophage colony-stimulating factor receptor (M-CSFR), CD115 Cluster of Differentiation 115 (CD115), C-FMS, CSFR, FIM2, FMS, and is a member of the type Ⅲ subfamily of receptor tyrosine kinases. M-CSF receptor, the product of the c-fms proto-oncogene, is a member of the type III subfamily of receptor tyrosine kinases that also includes receptors for SCF and PDGF. These receptors each contain five immunoglobulin-like domains in their extracellular domain (ECD) and a split kinase domain in their intracellular region. M-CSF receptor is expressed primarily on cells of the monocyte/macrophage lineage, dendritic cells, stem cells and in the developing placenta. M-CSF R engagement is continuously required for macrophage survival and regulates lineage decisions and maturation of monocytes, macrophages, osteoclasts and DC. M-CSF R and integrin alpha v beta 3 share signaling pathways during osteoclastogenesis and deletion of either causes osteopetrosis. In the brain, microglia expressing increased M-CSF R are concentrated with Alzheimers a beta peptide, but their role in pathogenesis is unclear.
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SKU: 82269752388

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Virginia Wharton
Omaha, US
★★★★★ 5
It is really well made and perfect for travel!
It is just like the picture and it is lovely. Plenty of room and under the tray it is large enough for changes with pendents. It is perfect for a girl and will be perfect for the amount of jewerly you take when traveling. Thank You!
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Reviewed in the United States on December 3, 2025
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Jamie C.
Belleville, US
★★★★★ 5
Very nice little box.
This is a great little jewelry box. I don’t have tons of jewelry right now, so this fits everything well, and the leather-look material is very nice. I like the simple design and organization, and it is a nice size to travel with. It looks really pretty sitting on my dresser and goes with the aesthetic of my home well.
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Reviewed in the United States on June 8, 2025
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Suly
West Palm Beach, US
★★★★★ 4
Pretty
Very nice simple jewelry box. My only issue is spacing to put necklaces is a bit tight, but there is plenty of room in this little guy. I put a lighter next to it, for size comparison.
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Reviewed in the United States on March 15, 2026
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Siddeek D. Ali
Battle Creek, US
★★★★★ 5
Great item
Great item
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Reviewed in the United States on May 4, 2026
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Kindle Customer
Bozeman, US
★★★★★ 5
Chic little box
Perfect size for area. Holds plenty small jewelry items. Secure closure.
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Reviewed in the United States on April 29, 2026

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