SKU: 93591417435

Phospho-AMPKα (Thr172) Recombinant Rabbit mAb (S-2216-10)

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Description

Phospho-AMPKα (Thr172) Recombinant Rabbit mAb (S-2216-10)Product Specification Host Rabbit Antigen Phospho AMPK (Thr172) Synonyms 5' AMP activated protein kinase catalytic subunit alpha; AMPK subunit alpha; Acetyl CoA carboxylase kinase (ACACA kinase); Hydroxymethylglutaryl CoA reductase kinase (HMGCR kinase); Tau protein kinase PRKAA1; PRKAA1; AMPK1 Immunogen Synthetic Peptide Location Cytoplasm, Nucleus Accession Q13131P54646 Clone Number S 2216 10 Antibody Type Recombinant mAb Isotype IgG Application WB

Product Specification


Host Rabbit
Antigen Phospho-AMPKα (Thr172)
Synonyms 5'-AMP-activated protein kinase catalytic subunit alpha; AMPK subunit alpha; Acetyl-CoA carboxylase kinase (ACACA kinase); Hydroxymethylglutaryl-CoA reductase kinase (HMGCR kinase); Tau-protein kinase PRKAA1; PRKAA1; AMPK1
Immunogen Synthetic Peptide
Location Cytoplasm, Nucleus
Accession Q13131、P54646
Clone Number S-2216-10
Antibody Type Recombinant mAb
Isotype IgG
Application WB
Reactivity Hu, Ms, Rt, Mk
Purification Protein A
Concentration 0.5 mg/ml
Conjugation Unconjugated
Physical Appearance Liquid
Storage Buffer

PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300

Stability & Storage

12 months from date of receipt / reconstitution, -20 °C as supplied

Dilution


application dilution species
Dot Blot 1:1000
WB 1:500-1:1000 Hu, Ms, Rt, Mk

Background

Phospho-AMPKα (Thr172) protein refers to the catalytic α-subunit of AMP-activated protein kinase that has been phosphorylated on threonine 172, a post-translational modification catalyzed primarily by the upstream kinase LKB1 (or CaMKK2 in response to calcium signals) that is essential for switching AMPK from an inactive to an active conformation; once phosphorylated, this evolutionarily conserved serine/threonine kinase acts as a master cellular energy sensor, triggering catabolic pathways such as fatty-acid oxidation and autophagy while simultaneously inhibiting energy-consuming anabolic processes like gluconeogenesis, lipogenesis and protein synthesis, thereby restoring ATP levels during metabolic stress, and its phosphorylation status is widely used as a biomarker for metabolic activity, exercise physiology, mitochondrial health and the efficacy of drugs ranging from metformin to direct AMPK activators in diabetes, cancer and cardiovascular research.

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SKU: 93591417435

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Jose Hernandez
Cuba, US
★★★★★ 3
Not confortable.
Size: 7.5, Color: Natural Snake
The straps kill your feet.
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Reviewed in the United States on February 6, 2026
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Reggi
Massapequa, US
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Beautiful and comfortable
Size: 8.5, Color: Raffia
These are beautiful shoes
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Bob T.
Natrona Heights, US
★★★★★ 5
Comfy and chic
Size: 7.5, Color: Ivory, Size: 7.5, Color: Ivory
I love these shoes for any outfit! They went perfect with my white baby shower dress
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Reviewed in the United States on December 26, 2025
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Belleville, US
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Beautiful heels
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Love these gerls
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Reviewed in the United States on January 27, 2026
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Massapequa, US
★★★★★ 1
Not enough material to make a shoe.
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Shoes are very thin. Hardly any materials. However, if that's what you like for the price.
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Reviewed in the United States on September 22, 2025

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