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Description
NGFR/TNFRSF16 Fc Chimera Protein, MouseProduct Specification Species Mouse Synonyms Gp80 LNGFRNGF ReceptorLow Affinity Neurotrophin Receptor P75NTRNerve Growth Factor Receptor (TNFR Superfamily Member 16)NGFRTNFR Superfamily Member 16Tumor Necrosis Factor Receptor Superfamily Member 16CD271CD271 AntigenLow Affinity Nerve Growth Factor ReceptorLow Affinity Nerve Growth Factor ReceptorP75 ICDNerve Growth Factor ReceptorP75(NTR)TNFRSF16P75NTR Accession Q9Z0W1 1 Amino Acid Sequence Lys32
Product Specification
| Species | Mouse |
| Synonyms | Gp80-LNGFR，NGF Receptor，Low Affinity Neurotrophin Receptor P75NTR，Nerve Growth Factor Receptor (TNFR Superfamily， Member 16)，NGFR，TNFR Superfamily， Member 16，Tumor Necrosis Factor Receptor Superfamily Member 16，CD271，CD271 Antigen，Low Affinity Nerve Growth Factor Receptor，Low-Affinity Nerve Growth Factor Receptor，P75 ICD，Nerve Growth Factor Receptor，P75(NTR)，TNFRSF16，P75NTR |
| Accession | Q9Z0W1-1 |
| Amino Acid Sequence | Lys32-Leu254, with C-hIgG Fc |
| Expression System | HEK293 |
| Molecular Weight | 70-90kDa (Reducing) |
| Purity | ＞95% by SDS-PAGE > 95% by SEC-HPLC |
| Endotoxin | <0.1EU/μg |
| Conjugation | Unconjugated |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | PBS, PH7.4, 5% trehalose |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles. |
| Reference | 1.Barker, P.A. and R.A. Murphy (1992) Molecular and Cellular Biochemistry 110:1. |
Background
p75 neurotrophin receptor, also named low affinity NGF receptor (NGF R), is a type I transmembrane protein that belongs to the tumor necrosis factor receptor family. The extracellular region contains four cysteine-rich domains and binds NGF, BDNF, NT-3 and NT-4 approximately equally with low affinity. The cytoplasmic region contains a subtype 2 death domain. NGF R expression has been shown to occur widely during development and in the adult. Expression has been detected in both neuronal and non-neuronal cells. NGF R was originally reported to function as a positive regulator of TrkA activity. NGF R has also been shown to signal by itself. Depending on its cellular environment, NGF R has now been shown to regulate cell migration, gene expression and to mediate apoptosis. Recombinant NGF R/Fc chimera binds NGF with high affinity and is a potent NGF antagonist. Naturally occurring truncated NGF R containing the extracellular domain and lacking the transmembrane or intracellular domain has been detected in vivo in urine, plasma and in amniotic fluid of humans and rats.
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4.6 ★★★★★
Based on 18 reviews
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Product Reviews
★★★★★ 3
Not Durable…Splintered….
Had to chuck these. I loved them at first but they are not durable. Scratched themselves up right away and then the mid sized one started to splinter. I didn’t even have it for very long before I had to get rid of them. Long enough to not be able to return. I prefer the bamboo as far as wood goes, but switched to an antibacterial. It’s crazy because I had the same cutting boards for years and in the past month I’ve had to replace them 3 times now. I was so disappointed because there were such amazing reviews. Sadly that was not the case for me. I give it a 3 because they are absolutely beautiful…..you get points for being beautiful I suppose in this world. But not durable. At least not for me.
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Reviewed in the United States on January 22, 2026
★★★★★ 5
Perfect cutting board set of 3
Very nice cutting boards, and I especially love the peace of mind knowing there is not harsh chemicals used to make these. Thank you!
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Reviewed in the United States on May 27, 2026
★★★★★ 5
Fascinating exploration of God's Word!
Urban Legends of the New Testament: 40 Common Misperceptions is an impressive work by David A. Croteau that discusses 40 "commonly circulated myths, repeated throughout the culture as common knowledge, but which isn't true."
But we're talking about the infallible Word of God, right? That is correct. But according to the author, certain passages of the New Testament have become victims of the notorious Urban Legend phenomena.
The titles of each chapter are the actual legends and are presented as if the author really believes what he is writing to be true. The reader will soon find out that is not the case. Croteau goes on to discuss the incorrect interpretation versus an accurate interpretation and then ends the chapter with his opinion of what the text means, followed by a practical application section.
The presentation and discussion of each myth is clear, although some are harder to piece through than others. The length of the chapters vary according to the history of the myth and depth of the discussion. Topics vary from the birth, life, and crucifixion of Jesus to Paul's profession, the plan of salvation, hell, divorce, money, pastors and their families, and cults. You can pick up the book and read only the chapters that interest you, although I do encourage you to read the introduction and epilogue.
The prologue discusses two types of legends: a mistaken-contains wrong information; misleading-those that need clarification. The cause and solution for urban legends of the New Testament come down to three components: Context, Greek, and Backgrounds. Croteau clearly discusses this at the end of the book and my only criticism is that I would have liked that information in the introduction. I believe it would have aided in my overall structure for comprehension.
Overall, the research was fascinating and I learned—a lot.
This quote from the final conclusion summarizes the purpose of this book:
"In the end our goal should be to interpret Scripture as accurately as possible, to apply that interpretation to our own lives, and to be transformed by God's Word so that our lives may bring glory to the One who rescued us from an eternal destiny in hell."
I highly recommend this book to all readers. Don't plan to read it in one sitting. Use it as a study guide and tool to inspire you to dig deeper into God's Word.
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Reviewed in the United States on January 12, 2016
★★★★★ 5
Only Orthodoxy Will Lead to Orthopraxy and Orthopathy
Format: Kindle
This book authored by David Croteau is truly an enjoyable yet at the same time a convicting read. Even though it was written about 10 years ago, the principles of interpretation advocated by him to deal with the "mistaken and misleading legends" are timeless. Out of the 40 legends, I have encountered at least half of them in the local church, writings and even seminary especially issues pertaining to salvation, Christian living and women's adornment.
The main takeaway is this: Just as there are three things that matter in property: "Location, Location, Location", similarly the three main things that matter in interpretation of the Word is: "Context, Greek, and Background Information", or even simpler: "Context, Context, Context". David Croteau has demonstrated in his 40 legends the utmost importance of context in correctly interpreting a particular passage which was unfortunately taken out of context. The interpretation can further be handled even more accurately by taking into account the Greek language and the socio-historical background behind the text. In fact, I have been focusing on these three elements in my hermeneutical approach whenever I come across passages which I need more understanding. I don't know Greek; but with the many useful online Greek tools nowadays, I can always do a word study which more or less balances my lacking of Greek knowledge. Also, the study of socio-historical background is extremely illuminating if one have access to these resources. Personally, I discover that a proper understanding of background information can eliminate most of the mistaken or misleading interpretation of a text.
Lastly, I totally agree with David Croteau's conclusion: "In the end our goal should be to interpret Scripture as accurately as possible, to apply that interpretation to our own lives, and to be transformed by God’s Word so that our lives may bring glory to the One who rescued us from an eternal destiny in hell." His conclusion reminds me of a phrase which I encountered years ago: "Orthodoxy Will Lead to Orthopraxy and Orthopathy." Indeed, only by "accurately handling the word of truth" (2 Tim 2:15) can we realise the necessity of holy living and the proper response that we should have towards our living God.
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Reviewed in the United States on April 6, 2025
★★★★★ 5
The book is also great in pointing to additional resources for further study
Format: Paperback
Other than the Bible, I hesitate to use the term "must read" for a book. This one is definitely a "should read" for anyone who teaches, preaches, or wants to minister more faithfully. The book is engaging, and offers both a negative (doesn't mean this) and positive (means this) response to common urban legends of the NT. You'll be surprised by some beliefs you had that you didn't even realize were not correct, or should be adjusted. The book is also great in pointing to additional resources for further study. Pastors, seminarians, and lay people will all benefit from this book.
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Reviewed in the United States on July 17, 2015